| Full name: secreted LY6/PLAUR domain containing 1 | Alias Symbol: ARS|ANUP|MDM|ArsB|LY6LS|LY6-MT | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 57152 | HGNC ID: HGNC:18746 | Ensembl Gene: ENSG00000126233 | OMIM ID: 606119 |
| Drug and gene relationship at DGIdb | |||
Expression of SLURP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLURP1 | 57152 | 214536_at | -3.8802 | 0.0399 | |
| GSE20347 | SLURP1 | 57152 | 214536_at | -4.9907 | 0.0000 | |
| GSE23400 | SLURP1 | 57152 | 214536_at | -3.6768 | 0.0000 | |
| GSE26886 | SLURP1 | 57152 | 214536_at | -3.5225 | 0.0000 | |
| GSE29001 | SLURP1 | 57152 | 214536_at | -4.4369 | 0.0000 | |
| GSE38129 | SLURP1 | 57152 | 214536_at | -3.8748 | 0.0000 | |
| GSE45670 | SLURP1 | 57152 | 214536_at | -2.2157 | 0.0030 | |
| GSE53622 | SLURP1 | 57152 | 65918 | -3.7990 | 0.0000 | |
| GSE53624 | SLURP1 | 57152 | 65918 | -3.9608 | 0.0000 | |
| GSE63941 | SLURP1 | 57152 | 214536_at | 0.2137 | 0.5677 | |
| GSE77861 | SLURP1 | 57152 | 214536_at | -3.5426 | 0.0050 | |
| GSE97050 | SLURP1 | 57152 | A_33_P3258801 | -2.2535 | 0.0762 | |
| SRP007169 | SLURP1 | 57152 | RNAseq | -10.4583 | 0.0000 | |
| SRP008496 | SLURP1 | 57152 | RNAseq | -7.2282 | 0.0000 | |
| SRP064894 | SLURP1 | 57152 | RNAseq | -4.7536 | 0.0000 | |
| SRP133303 | SLURP1 | 57152 | RNAseq | -6.5838 | 0.0000 | |
| SRP159526 | SLURP1 | 57152 | RNAseq | -5.5045 | 0.0000 | |
| TCGA | SLURP1 | 57152 | RNAseq | 0.1936 | 0.7459 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by SLURP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLURP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLURP1 | 57152 | 16 | 1 | 13 | |
| GSE20123 | SLURP1 | 57152 | 17 | 1 | 12 | |
| GSE43470 | SLURP1 | 57152 | 17 | 2 | 24 | |
| GSE46452 | SLURP1 | 57152 | 27 | 0 | 32 | |
| GSE47630 | SLURP1 | 57152 | 23 | 1 | 16 | |
| GSE54993 | SLURP1 | 57152 | 0 | 25 | 45 | |
| GSE54994 | SLURP1 | 57152 | 39 | 1 | 13 | |
| GSE60625 | SLURP1 | 57152 | 3 | 4 | 4 | |
| GSE74703 | SLURP1 | 57152 | 15 | 1 | 20 | |
| GSE74704 | SLURP1 | 57152 | 10 | 0 | 10 | |
| TCGA | SLURP1 | 57152 | 63 | 2 | 31 |
Total number of gains: 230; Total number of losses: 38; Total Number of normals: 220.
Somatic mutations of SLURP1:
Generating mutation plots.
Highly correlated genes for SLURP1:
Showing top 20/1350 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLURP1 | SPINK7 | 0.935521 | 8 | 0 | 8 |
| SLURP1 | SPINK5 | 0.922131 | 12 | 0 | 12 |
| SLURP1 | VSIG10L | 0.919997 | 7 | 0 | 7 |
| SLURP1 | CRNN | 0.919967 | 12 | 0 | 12 |
| SLURP1 | TGM3 | 0.911733 | 12 | 0 | 12 |
| SLURP1 | EHD3 | 0.901869 | 10 | 0 | 10 |
| SLURP1 | CXCR2 | 0.897856 | 10 | 0 | 10 |
| SLURP1 | CLIC3 | 0.897757 | 10 | 0 | 10 |
| SLURP1 | TMPRSS11B | 0.897672 | 8 | 0 | 8 |
| SLURP1 | SLC16A6 | 0.896191 | 10 | 0 | 10 |
| SLURP1 | NCCRP1 | 0.895613 | 4 | 0 | 4 |
| SLURP1 | SCEL | 0.889034 | 13 | 0 | 12 |
| SLURP1 | CNFN | 0.888267 | 8 | 0 | 8 |
| SLURP1 | IL36A | 0.886993 | 11 | 0 | 11 |
| SLURP1 | ECM1 | 0.885993 | 12 | 0 | 12 |
| SLURP1 | EPS8L2 | 0.884172 | 11 | 0 | 11 |
| SLURP1 | CRCT1 | 0.881829 | 12 | 0 | 12 |
| SLURP1 | GYS2 | 0.879885 | 10 | 0 | 10 |
| SLURP1 | CSTB | 0.879653 | 12 | 0 | 12 |
| SLURP1 | GDPD3 | 0.877225 | 12 | 0 | 11 |
For details and further investigation, click here
