| Full name: ALG9 alpha-1,2-mannosyltransferase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q23.1 | ||
| Entrez ID: 79796 | HGNC ID: HGNC:15672 | Ensembl Gene: ENSG00000086848 | OMIM ID: 606941 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ALG9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALG9 | 79796 | 219374_s_at | -0.5125 | 0.0660 | |
| GSE20347 | ALG9 | 79796 | 219374_s_at | -1.0663 | 0.0000 | |
| GSE23400 | ALG9 | 79796 | 219374_s_at | -0.2064 | 0.0001 | |
| GSE26886 | ALG9 | 79796 | 228817_at | -0.5931 | 0.0461 | |
| GSE29001 | ALG9 | 79796 | 219374_s_at | -0.8247 | 0.0099 | |
| GSE38129 | ALG9 | 79796 | 219374_s_at | -0.7921 | 0.0000 | |
| GSE45670 | ALG9 | 79796 | 219374_s_at | -0.3876 | 0.0046 | |
| GSE53622 | ALG9 | 79796 | 17893 | -0.5258 | 0.0000 | |
| GSE53624 | ALG9 | 79796 | 17893 | -0.5357 | 0.0001 | |
| GSE63941 | ALG9 | 79796 | 219374_s_at | -0.0330 | 0.9498 | |
| GSE77861 | ALG9 | 79796 | 219374_s_at | -0.3964 | 0.1229 | |
| GSE97050 | ALG9 | 79796 | A_24_P795594 | -0.2250 | 0.3909 | |
| SRP007169 | ALG9 | 79796 | RNAseq | -1.1117 | 0.0063 | |
| SRP008496 | ALG9 | 79796 | RNAseq | -0.8905 | 0.0001 | |
| SRP064894 | ALG9 | 79796 | RNAseq | -0.2917 | 0.0140 | |
| SRP133303 | ALG9 | 79796 | RNAseq | -0.4326 | 0.0001 | |
| SRP159526 | ALG9 | 79796 | RNAseq | -0.3501 | 0.1573 | |
| SRP193095 | ALG9 | 79796 | RNAseq | -0.5916 | 0.0000 | |
| SRP219564 | ALG9 | 79796 | RNAseq | -0.4667 | 0.1634 | |
| TCGA | ALG9 | 79796 | RNAseq | -0.2617 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ALG9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALG9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALG9 | 79796 | 0 | 12 | 18 | |
| GSE20123 | ALG9 | 79796 | 0 | 12 | 18 | |
| GSE43470 | ALG9 | 79796 | 2 | 6 | 35 | |
| GSE46452 | ALG9 | 79796 | 3 | 26 | 30 | |
| GSE47630 | ALG9 | 79796 | 2 | 19 | 19 | |
| GSE54993 | ALG9 | 79796 | 10 | 0 | 60 | |
| GSE54994 | ALG9 | 79796 | 5 | 19 | 29 | |
| GSE60625 | ALG9 | 79796 | 0 | 3 | 8 | |
| GSE74703 | ALG9 | 79796 | 1 | 4 | 31 | |
| GSE74704 | ALG9 | 79796 | 0 | 8 | 12 | |
| TCGA | ALG9 | 79796 | 6 | 48 | 42 |
Total number of gains: 29; Total number of losses: 157; Total Number of normals: 302.
Somatic mutations of ALG9:
Generating mutation plots.
Highly correlated genes for ALG9:
Showing top 20/1263 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALG9 | C2orf16 | 0.862308 | 3 | 0 | 3 |
| ALG9 | UBQLN1 | 0.765226 | 3 | 0 | 3 |
| ALG9 | NUDCD3 | 0.764768 | 3 | 0 | 3 |
| ALG9 | TOM1L1 | 0.743622 | 3 | 0 | 3 |
| ALG9 | OR7A10 | 0.727109 | 4 | 0 | 4 |
| ALG9 | ARMCX5 | 0.725861 | 3 | 0 | 3 |
| ALG9 | CHM | 0.72573 | 3 | 0 | 3 |
| ALG9 | SCAMP1 | 0.720115 | 3 | 0 | 3 |
| ALG9 | SNX14 | 0.719526 | 3 | 0 | 3 |
| ALG9 | CNTNAP3 | 0.719074 | 3 | 0 | 3 |
| ALG9 | SLC22A15 | 0.714357 | 5 | 0 | 5 |
| ALG9 | ATP6V1H | 0.710051 | 4 | 0 | 4 |
| ALG9 | SAMD8 | 0.70729 | 3 | 0 | 3 |
| ALG9 | KCNG2 | 0.702139 | 6 | 0 | 5 |
| ALG9 | PPP1R36 | 0.70154 | 3 | 0 | 3 |
| ALG9 | DNASE1L1 | 0.69859 | 3 | 0 | 3 |
| ALG9 | PHYH | 0.697795 | 3 | 0 | 3 |
| ALG9 | SLC7A4 | 0.696497 | 4 | 0 | 3 |
| ALG9 | SLC10A7 | 0.695601 | 3 | 0 | 3 |
| ALG9 | WDR11 | 0.69542 | 3 | 0 | 3 |
For details and further investigation, click here
