| Full name: phytanoyl-CoA 2-hydroxylase | Alias Symbol: PAHX|RD|PHYH1 | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 5264 | HGNC ID: HGNC:8940 | Ensembl Gene: ENSG00000107537 | OMIM ID: 602026 |
| Drug and gene relationship at DGIdb | |||
Expression of PHYH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHYH | 5264 | 203335_at | -0.5819 | 0.4702 | |
| GSE20347 | PHYH | 5264 | 203335_at | 0.1746 | 0.6572 | |
| GSE23400 | PHYH | 5264 | 203335_at | -0.0114 | 0.9351 | |
| GSE26886 | PHYH | 5264 | 203335_at | 1.5959 | 0.0001 | |
| GSE29001 | PHYH | 5264 | 203335_at | 0.0465 | 0.9267 | |
| GSE38129 | PHYH | 5264 | 203335_at | -0.2312 | 0.5420 | |
| GSE45670 | PHYH | 5264 | 203335_at | -0.7398 | 0.0080 | |
| GSE53622 | PHYH | 5264 | 139552 | -0.4265 | 0.0011 | |
| GSE53624 | PHYH | 5264 | 139552 | -0.1967 | 0.1362 | |
| GSE63941 | PHYH | 5264 | 203335_at | -0.8466 | 0.2083 | |
| GSE77861 | PHYH | 5264 | 203335_at | 0.0199 | 0.9643 | |
| GSE97050 | PHYH | 5264 | A_23_P115919 | -0.4323 | 0.3531 | |
| SRP007169 | PHYH | 5264 | RNAseq | 0.7155 | 0.2633 | |
| SRP064894 | PHYH | 5264 | RNAseq | 0.1615 | 0.5747 | |
| SRP133303 | PHYH | 5264 | RNAseq | -0.0289 | 0.8969 | |
| SRP159526 | PHYH | 5264 | RNAseq | -0.0288 | 0.9072 | |
| SRP193095 | PHYH | 5264 | RNAseq | -1.0614 | 0.0033 | |
| SRP219564 | PHYH | 5264 | RNAseq | -0.4113 | 0.5565 | |
| TCGA | PHYH | 5264 | RNAseq | -0.5542 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by PHYH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHYH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHYH | 5264 | 4 | 8 | 18 | |
| GSE20123 | PHYH | 5264 | 4 | 7 | 19 | |
| GSE43470 | PHYH | 5264 | 3 | 5 | 35 | |
| GSE46452 | PHYH | 5264 | 2 | 14 | 43 | |
| GSE47630 | PHYH | 5264 | 6 | 14 | 20 | |
| GSE54993 | PHYH | 5264 | 11 | 1 | 58 | |
| GSE54994 | PHYH | 5264 | 4 | 9 | 40 | |
| GSE60625 | PHYH | 5264 | 0 | 0 | 11 | |
| GSE74703 | PHYH | 5264 | 2 | 3 | 31 | |
| GSE74704 | PHYH | 5264 | 0 | 6 | 14 | |
| TCGA | PHYH | 5264 | 21 | 24 | 51 |
Total number of gains: 57; Total number of losses: 91; Total Number of normals: 340.
Somatic mutations of PHYH:
Generating mutation plots.
Highly correlated genes for PHYH:
Showing top 20/942 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHYH | SYNC | 0.808791 | 4 | 0 | 4 |
| PHYH | C5orf24 | 0.788988 | 3 | 0 | 3 |
| PHYH | TCEAL6 | 0.764234 | 3 | 0 | 3 |
| PHYH | SUCLG2-AS1 | 0.738504 | 3 | 0 | 3 |
| PHYH | MRPL9 | 0.734596 | 3 | 0 | 3 |
| PHYH | USP42 | 0.733478 | 3 | 0 | 3 |
| PHYH | THRB | 0.732993 | 4 | 0 | 4 |
| PHYH | CREB5 | 0.720527 | 3 | 0 | 3 |
| PHYH | CUTA | 0.719115 | 3 | 0 | 3 |
| PHYH | ANAPC16 | 0.718002 | 3 | 0 | 3 |
| PHYH | LRRCC1 | 0.717411 | 3 | 0 | 3 |
| PHYH | EIF5B | 0.715574 | 3 | 0 | 3 |
| PHYH | NT5E | 0.713161 | 3 | 0 | 3 |
| PHYH | EID3 | 0.71233 | 3 | 0 | 3 |
| PHYH | COX20 | 0.708769 | 3 | 0 | 3 |
| PHYH | MYO5A | 0.708045 | 3 | 0 | 3 |
| PHYH | RGMB | 0.707193 | 5 | 0 | 4 |
| PHYH | PCDH9 | 0.704643 | 5 | 0 | 5 |
| PHYH | ZNF383 | 0.70418 | 3 | 0 | 3 |
| PHYH | SLMAP | 0.702919 | 4 | 0 | 3 |
For details and further investigation, click here
