| Full name: sterile alpha motif domain containing 8 | Alias Symbol: FLJ25082|SMSr | ||
| Type: protein-coding gene | Cytoband: 10q22.2 | ||
| Entrez ID: 142891 | HGNC ID: HGNC:26320 | Ensembl Gene: ENSG00000156671 | OMIM ID: 611575 |
| Drug and gene relationship at DGIdb | |||
Expression of SAMD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAMD8 | 142891 | 225950_at | -0.5798 | 0.2055 | |
| GSE26886 | SAMD8 | 142891 | 225950_at | -0.7915 | 0.0068 | |
| GSE45670 | SAMD8 | 142891 | 225950_at | -0.5099 | 0.0095 | |
| GSE53622 | SAMD8 | 142891 | 41434 | -0.7758 | 0.0000 | |
| GSE53624 | SAMD8 | 142891 | 41434 | -0.6913 | 0.0000 | |
| GSE63941 | SAMD8 | 142891 | 225950_at | -1.2918 | 0.0110 | |
| GSE77861 | SAMD8 | 142891 | 225950_at | -0.5620 | 0.1375 | |
| GSE97050 | SAMD8 | 142891 | A_23_P63870 | -0.3449 | 0.5802 | |
| SRP007169 | SAMD8 | 142891 | RNAseq | -1.0711 | 0.0178 | |
| SRP008496 | SAMD8 | 142891 | RNAseq | -0.7640 | 0.0024 | |
| SRP064894 | SAMD8 | 142891 | RNAseq | -1.1167 | 0.0000 | |
| SRP133303 | SAMD8 | 142891 | RNAseq | -0.2174 | 0.2881 | |
| SRP159526 | SAMD8 | 142891 | RNAseq | -0.8870 | 0.0257 | |
| SRP193095 | SAMD8 | 142891 | RNAseq | -0.6356 | 0.0001 | |
| SRP219564 | SAMD8 | 142891 | RNAseq | -1.1140 | 0.0148 | |
| TCGA | SAMD8 | 142891 | RNAseq | 0.1015 | 0.2676 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SAMD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAMD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAMD8 | 142891 | 3 | 5 | 22 | |
| GSE20123 | SAMD8 | 142891 | 3 | 4 | 23 | |
| GSE43470 | SAMD8 | 142891 | 2 | 7 | 34 | |
| GSE46452 | SAMD8 | 142891 | 0 | 11 | 48 | |
| GSE47630 | SAMD8 | 142891 | 2 | 14 | 24 | |
| GSE54993 | SAMD8 | 142891 | 7 | 0 | 63 | |
| GSE54994 | SAMD8 | 142891 | 2 | 10 | 41 | |
| GSE60625 | SAMD8 | 142891 | 0 | 0 | 11 | |
| GSE74703 | SAMD8 | 142891 | 2 | 4 | 30 | |
| GSE74704 | SAMD8 | 142891 | 1 | 2 | 17 | |
| TCGA | SAMD8 | 142891 | 11 | 23 | 62 |
Total number of gains: 33; Total number of losses: 80; Total Number of normals: 375.
Somatic mutations of SAMD8:
Generating mutation plots.
Highly correlated genes for SAMD8:
Showing top 20/921 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAMD8 | PDIK1L | 0.799022 | 3 | 0 | 3 |
| SAMD8 | EXOC2 | 0.786609 | 3 | 0 | 3 |
| SAMD8 | RAB11FIP2 | 0.767951 | 3 | 0 | 3 |
| SAMD8 | SEC23IP | 0.767543 | 3 | 0 | 3 |
| SAMD8 | SNX7 | 0.761889 | 3 | 0 | 3 |
| SAMD8 | TRIP11 | 0.760998 | 3 | 0 | 3 |
| SAMD8 | RASA1 | 0.754367 | 3 | 0 | 3 |
| SAMD8 | MRPL39 | 0.752953 | 3 | 0 | 3 |
| SAMD8 | WDR61 | 0.750503 | 3 | 0 | 3 |
| SAMD8 | PNRC2 | 0.750065 | 3 | 0 | 3 |
| SAMD8 | LANCL1 | 0.749762 | 3 | 0 | 3 |
| SAMD8 | ZNF416 | 0.740157 | 3 | 0 | 3 |
| SAMD8 | PDS5A | 0.736008 | 3 | 0 | 3 |
| SAMD8 | VDAC2 | 0.730066 | 7 | 0 | 7 |
| SAMD8 | BCAS2 | 0.726307 | 3 | 0 | 3 |
| SAMD8 | PTAR1 | 0.723533 | 3 | 0 | 3 |
| SAMD8 | ERI2 | 0.712061 | 3 | 0 | 3 |
| SAMD8 | NFKB1 | 0.711973 | 3 | 0 | 3 |
| SAMD8 | IMPACT | 0.711431 | 3 | 0 | 3 |
| SAMD8 | AKR7A2 | 0.711336 | 3 | 0 | 3 |
For details and further investigation, click here
