| Full name: WD repeat domain 11 | Alias Symbol: KIAA1351|FLJ10506|WDR15|HH14|DR11|SRI1 | ||
| Type: protein-coding gene | Cytoband: 10q26.12 | ||
| Entrez ID: 55717 | HGNC ID: HGNC:13831 | Ensembl Gene: ENSG00000120008 | OMIM ID: 606417 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR11 | 55717 | 218090_s_at | -0.1588 | 0.5947 | |
| GSE20347 | WDR11 | 55717 | 218090_s_at | -0.1087 | 0.4180 | |
| GSE23400 | WDR11 | 55717 | 218090_s_at | 0.1119 | 0.1948 | |
| GSE26886 | WDR11 | 55717 | 218090_s_at | -0.2019 | 0.4374 | |
| GSE29001 | WDR11 | 55717 | 218090_s_at | 0.0393 | 0.8565 | |
| GSE38129 | WDR11 | 55717 | 218090_s_at | -0.1180 | 0.2946 | |
| GSE45670 | WDR11 | 55717 | 218090_s_at | -0.0502 | 0.7191 | |
| GSE53622 | WDR11 | 55717 | 90588 | -0.0935 | 0.1872 | |
| GSE53624 | WDR11 | 55717 | 90588 | -0.1935 | 0.0020 | |
| GSE63941 | WDR11 | 55717 | 218090_s_at | -0.5995 | 0.1227 | |
| GSE77861 | WDR11 | 55717 | 218090_s_at | -0.1987 | 0.5922 | |
| GSE97050 | WDR11 | 55717 | A_23_P63929 | 0.0135 | 0.9699 | |
| SRP007169 | WDR11 | 55717 | RNAseq | -0.5770 | 0.1274 | |
| SRP008496 | WDR11 | 55717 | RNAseq | -0.5192 | 0.0190 | |
| SRP064894 | WDR11 | 55717 | RNAseq | -0.2098 | 0.3658 | |
| SRP133303 | WDR11 | 55717 | RNAseq | -0.0390 | 0.7136 | |
| SRP159526 | WDR11 | 55717 | RNAseq | -0.4909 | 0.2052 | |
| SRP193095 | WDR11 | 55717 | RNAseq | -0.2145 | 0.0020 | |
| SRP219564 | WDR11 | 55717 | RNAseq | -0.2476 | 0.2895 | |
| TCGA | WDR11 | 55717 | RNAseq | -0.1592 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDR11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR11 | 55717 | 3 | 6 | 21 | |
| GSE20123 | WDR11 | 55717 | 3 | 6 | 21 | |
| GSE43470 | WDR11 | 55717 | 0 | 9 | 34 | |
| GSE46452 | WDR11 | 55717 | 0 | 11 | 48 | |
| GSE47630 | WDR11 | 55717 | 2 | 14 | 24 | |
| GSE54993 | WDR11 | 55717 | 8 | 1 | 61 | |
| GSE54994 | WDR11 | 55717 | 1 | 9 | 43 | |
| GSE60625 | WDR11 | 55717 | 0 | 0 | 11 | |
| GSE74703 | WDR11 | 55717 | 0 | 6 | 30 | |
| GSE74704 | WDR11 | 55717 | 2 | 2 | 16 | |
| TCGA | WDR11 | 55717 | 4 | 28 | 64 |
Total number of gains: 23; Total number of losses: 92; Total Number of normals: 373.
Somatic mutations of WDR11:
Generating mutation plots.
Highly correlated genes for WDR11:
Showing top 20/389 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR11 | PPIL3 | 0.746325 | 4 | 0 | 4 |
| WDR11 | GOLGA4 | 0.740982 | 3 | 0 | 3 |
| WDR11 | TRAPPC6B | 0.735566 | 3 | 0 | 3 |
| WDR11 | SMARCAD1 | 0.734574 | 3 | 0 | 3 |
| WDR11 | SLC25A46 | 0.734171 | 3 | 0 | 3 |
| WDR11 | CPT2 | 0.733738 | 3 | 0 | 3 |
| WDR11 | BDH2 | 0.726615 | 3 | 0 | 3 |
| WDR11 | SLC25A43 | 0.72555 | 3 | 0 | 3 |
| WDR11 | TCF7L2 | 0.715457 | 3 | 0 | 3 |
| WDR11 | TOR1AIP2 | 0.713499 | 3 | 0 | 3 |
| WDR11 | OSBPL8 | 0.712386 | 4 | 0 | 4 |
| WDR11 | GPD2 | 0.711569 | 3 | 0 | 3 |
| WDR11 | CMTM6 | 0.705148 | 4 | 0 | 4 |
| WDR11 | RPP30 | 0.703004 | 3 | 0 | 3 |
| WDR11 | FAM200A | 0.702541 | 3 | 0 | 3 |
| WDR11 | LMBRD2 | 0.701702 | 3 | 0 | 3 |
| WDR11 | USP33 | 0.700154 | 4 | 0 | 4 |
| WDR11 | ZBTB44 | 0.700136 | 3 | 0 | 3 |
| WDR11 | LYRM7 | 0.699709 | 3 | 0 | 3 |
| WDR11 | PDCD6IP | 0.698696 | 3 | 0 | 3 |
For details and further investigation, click here
