| Full name: ubiquilin 1 | Alias Symbol: DSK2|PLIC-1|XDRP1|DA41 | ||
| Type: protein-coding gene | Cytoband: 9q21.32 | ||
| Entrez ID: 29979 | HGNC ID: HGNC:12508 | Ensembl Gene: ENSG00000135018 | OMIM ID: 605046 |
| Drug and gene relationship at DGIdb | |||
Expression of UBQLN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBQLN1 | 29979 | 222990_at | -0.3381 | 0.1065 | |
| GSE26886 | UBQLN1 | 29979 | 222990_at | -0.6095 | 0.0091 | |
| GSE45670 | UBQLN1 | 29979 | 222990_at | -0.1592 | 0.2200 | |
| GSE53622 | UBQLN1 | 29979 | 36827 | 0.0257 | 0.7186 | |
| GSE53624 | UBQLN1 | 29979 | 36827 | 0.1699 | 0.0080 | |
| GSE63941 | UBQLN1 | 29979 | 222990_at | -0.2691 | 0.4764 | |
| GSE77861 | UBQLN1 | 29979 | 222990_at | 0.1379 | 0.4078 | |
| GSE97050 | UBQLN1 | 29979 | A_24_P329600 | 0.1842 | 0.4761 | |
| SRP007169 | UBQLN1 | 29979 | RNAseq | 0.0507 | 0.8959 | |
| SRP008496 | UBQLN1 | 29979 | RNAseq | 0.0542 | 0.7677 | |
| SRP064894 | UBQLN1 | 29979 | RNAseq | 0.1501 | 0.3706 | |
| SRP133303 | UBQLN1 | 29979 | RNAseq | 0.3166 | 0.0448 | |
| SRP159526 | UBQLN1 | 29979 | RNAseq | -0.0138 | 0.9397 | |
| SRP193095 | UBQLN1 | 29979 | RNAseq | 0.2087 | 0.0878 | |
| SRP219564 | UBQLN1 | 29979 | RNAseq | -0.1296 | 0.5803 | |
| TCGA | UBQLN1 | 29979 | RNAseq | 0.0504 | 0.2528 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBQLN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBQLN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBQLN1 | 29979 | 5 | 10 | 15 | |
| GSE20123 | UBQLN1 | 29979 | 5 | 10 | 15 | |
| GSE43470 | UBQLN1 | 29979 | 6 | 3 | 34 | |
| GSE46452 | UBQLN1 | 29979 | 6 | 14 | 39 | |
| GSE47630 | UBQLN1 | 29979 | 1 | 18 | 21 | |
| GSE54993 | UBQLN1 | 29979 | 4 | 2 | 64 | |
| GSE54994 | UBQLN1 | 29979 | 5 | 12 | 36 | |
| GSE60625 | UBQLN1 | 29979 | 0 | 0 | 11 | |
| GSE74703 | UBQLN1 | 29979 | 5 | 3 | 28 | |
| GSE74704 | UBQLN1 | 29979 | 3 | 7 | 10 | |
| TCGA | UBQLN1 | 29979 | 20 | 28 | 48 |
Total number of gains: 60; Total number of losses: 107; Total Number of normals: 321.
Somatic mutations of UBQLN1:
Generating mutation plots.
Highly correlated genes for UBQLN1:
Showing top 20/276 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBQLN1 | BECN1 | 0.852054 | 3 | 0 | 3 |
| UBQLN1 | CHMP2B | 0.805544 | 3 | 0 | 3 |
| UBQLN1 | VPS29 | 0.793407 | 3 | 0 | 3 |
| UBQLN1 | COPS2 | 0.786735 | 3 | 0 | 3 |
| UBQLN1 | PSMD7 | 0.785204 | 3 | 0 | 3 |
| UBQLN1 | DCTN2 | 0.774847 | 3 | 0 | 3 |
| UBQLN1 | DOCK9 | 0.773815 | 3 | 0 | 3 |
| UBQLN1 | CTTNBP2NL | 0.773778 | 3 | 0 | 3 |
| UBQLN1 | RORA | 0.771696 | 3 | 0 | 3 |
| UBQLN1 | PPM1D | 0.768619 | 3 | 0 | 3 |
| UBQLN1 | CHMP2A | 0.76788 | 3 | 0 | 3 |
| UBQLN1 | BACH1 | 0.766555 | 3 | 0 | 3 |
| UBQLN1 | ALG9 | 0.765226 | 3 | 0 | 3 |
| UBQLN1 | SLC16A14 | 0.763015 | 3 | 0 | 3 |
| UBQLN1 | AZI2 | 0.761223 | 3 | 0 | 3 |
| UBQLN1 | UEVLD | 0.760388 | 3 | 0 | 3 |
| UBQLN1 | FAM114A2 | 0.758489 | 3 | 0 | 3 |
| UBQLN1 | UBE2D2 | 0.755046 | 3 | 0 | 3 |
| UBQLN1 | CEPT1 | 0.751849 | 3 | 0 | 3 |
| UBQLN1 | CUL3 | 0.751454 | 3 | 0 | 3 |
For details and further investigation, click here
