| Full name: alpha-1-microglobulin/bikunin precursor | Alias Symbol: UTI|HCP|EDC1|HI30|IATIL|ITILC | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 259 | HGNC ID: HGNC:453 | Ensembl Gene: ENSG00000106927 | OMIM ID: 176870 |
| Drug and gene relationship at DGIdb | |||
Expression of AMBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMBP | 259 | 214425_at | 0.2103 | 0.2988 | |
| GSE20347 | AMBP | 259 | 214425_at | -0.1453 | 0.1000 | |
| GSE23400 | AMBP | 259 | 214425_at | -0.1203 | 0.0006 | |
| GSE26886 | AMBP | 259 | 214425_at | 0.1279 | 0.2213 | |
| GSE29001 | AMBP | 259 | 214425_at | -0.1235 | 0.4107 | |
| GSE38129 | AMBP | 259 | 214425_at | -0.2274 | 0.0050 | |
| GSE45670 | AMBP | 259 | 214425_at | 0.0501 | 0.6170 | |
| GSE53622 | AMBP | 259 | 99305 | -0.1843 | 0.1006 | |
| GSE53624 | AMBP | 259 | 99305 | -0.1027 | 0.1259 | |
| GSE63941 | AMBP | 259 | 214425_at | 0.0666 | 0.6867 | |
| GSE77861 | AMBP | 259 | 214425_at | -0.0917 | 0.3913 | |
| TCGA | AMBP | 259 | RNAseq | -3.4444 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AMBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AMBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMBP | 259 | 3 | 10 | 17 | |
| GSE20123 | AMBP | 259 | 3 | 10 | 17 | |
| GSE43470 | AMBP | 259 | 4 | 3 | 36 | |
| GSE46452 | AMBP | 259 | 6 | 13 | 40 | |
| GSE47630 | AMBP | 259 | 3 | 16 | 21 | |
| GSE54993 | AMBP | 259 | 3 | 3 | 64 | |
| GSE54994 | AMBP | 259 | 9 | 9 | 35 | |
| GSE60625 | AMBP | 259 | 0 | 0 | 11 | |
| GSE74703 | AMBP | 259 | 4 | 3 | 29 | |
| GSE74704 | AMBP | 259 | 2 | 7 | 11 | |
| TCGA | AMBP | 259 | 26 | 22 | 48 |
Total number of gains: 63; Total number of losses: 96; Total Number of normals: 329.
Somatic mutations of AMBP:
Generating mutation plots.
Highly correlated genes for AMBP:
Showing top 20/579 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMBP | ATRNL1 | 0.69811 | 3 | 0 | 3 |
| AMBP | ART1 | 0.694105 | 4 | 0 | 3 |
| AMBP | LINC00652 | 0.677786 | 4 | 0 | 3 |
| AMBP | CMKLR1 | 0.677574 | 3 | 0 | 3 |
| AMBP | EDN2 | 0.676391 | 3 | 0 | 3 |
| AMBP | CPA2 | 0.667966 | 3 | 0 | 3 |
| AMBP | EMC10 | 0.655441 | 4 | 0 | 3 |
| AMBP | TNS4 | 0.651136 | 3 | 0 | 3 |
| AMBP | MOGAT3 | 0.647668 | 3 | 0 | 3 |
| AMBP | DRP2 | 0.645151 | 5 | 0 | 5 |
| AMBP | CRHR2 | 0.644501 | 4 | 0 | 4 |
| AMBP | SSTR4 | 0.644436 | 4 | 0 | 3 |
| AMBP | ADRB1 | 0.642576 | 3 | 0 | 3 |
| AMBP | CYP2A7 | 0.636083 | 5 | 0 | 4 |
| AMBP | CYP4A11 | 0.63492 | 6 | 0 | 5 |
| AMBP | RCVRN | 0.634142 | 6 | 0 | 5 |
| AMBP | CD70 | 0.632945 | 3 | 0 | 3 |
| AMBP | CYP19A1 | 0.632207 | 5 | 0 | 5 |
| AMBP | ZNF460 | 0.631188 | 5 | 0 | 4 |
| AMBP | SIPA1 | 0.630754 | 3 | 0 | 3 |
For details and further investigation, click here
