EMC10

 

Full name: ER membrane protein complex subunit 10 Alias Symbol: INM02|HSS1|HSM1
Type: protein-coding gene Cytoband: 19q13.33
Entrez ID: 284361 HGNC ID: HGNC:27609 Ensembl Gene: ENSG00000161671 OMIM ID: 614545
Drug and gene relationship at DGIdb

 

Expression of EMC10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 EMC10 284361 224727_at 0.5729 0.1972
GSE20347 EMC10 284361 222345_at 0.0142 0.8650
GSE23400 EMC10 284361 222345_at 0.0000 0.9999
GSE26886 EMC10 284361 224727_at 0.2205 0.0448
GSE29001 EMC10 284361 222345_at 0.0430 0.8775
GSE38129 EMC10 284361 222345_at 0.0158 0.8382
GSE45670 EMC10 284361 224727_at 0.3246 0.0037
GSE53622 EMC10 284361 28207 0.3378 0.0000
GSE53624 EMC10 284361 28207 0.2488 0.0005
GSE63941 EMC10 284361 224727_at 0.3706 0.5604
GSE77861 EMC10 284361 224727_at 0.2486 0.1449
SRP007169 EMC10 284361 RNAseq -0.0225 0.9544
SRP008496 EMC10 284361 RNAseq 0.0678 0.7905
SRP064894 EMC10 284361 RNAseq 0.5003 0.0590
SRP133303 EMC10 284361 RNAseq 0.5897 0.0001
SRP159526 EMC10 284361 RNAseq 0.7065 0.0223
SRP193095 EMC10 284361 RNAseq 0.3952 0.0055
SRP219564 EMC10 284361 RNAseq 0.5835 0.1478

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by EMC10 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of EMC10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 EMC10 284361 3 4 23
GSE20123 EMC10 284361 3 3 24
GSE43470 EMC10 284361 4 11 28
GSE46452 EMC10 284361 45 1 13
GSE47630 EMC10 284361 9 6 25
GSE54993 EMC10 284361 17 4 49
GSE54994 EMC10 284361 4 14 35
GSE60625 EMC10 284361 9 0 2
GSE74703 EMC10 284361 4 7 25
GSE74704 EMC10 284361 3 1 16
TCGA EMC10 284361 14 19 63

Total number of gains: 115; Total number of losses: 70; Total Number of normals: 303.  

 

Somatic mutations of EMC10:

 

Generating mutation plots.

 

Highly correlated genes for EMC10:

 

Showing top 20/509 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
EMC10SLC39A30.745592303
EMC10ZMIZ20.744656303
EMC10MYH90.704244303
EMC10USP210.703247303
EMC10NUP2100.693332303
EMC10SMG50.691258303
EMC10TNFRSF1A0.688443303
EMC10COL7A10.687794303
EMC10POLD10.686993504
EMC10TAGLN20.684797505
EMC10MRPL140.68479303
EMC10RBM420.684787505
EMC10ALDH16A10.683986505
EMC10PTOV10.681667505
EMC10JRK0.675819303
EMC10PPP1R370.675216303
EMC10CACTIN0.672433605
EMC10SF3B40.671745504
EMC10MED150.671123403
EMC10MAF10.671105504

For details and further investigation, click here