| Full name: monoacylglycerol O-acyltransferase 3 | Alias Symbol: DC7|MGAT3|DGAT2L2 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 346606 | HGNC ID: HGNC:23249 | Ensembl Gene: ENSG00000106384 | OMIM ID: 610184 |
| Drug and gene relationship at DGIdb | |||
Expression of MOGAT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOGAT3 | 346606 | 234850_at | 0.0844 | 0.7231 | |
| GSE26886 | MOGAT3 | 346606 | 234850_at | 0.2614 | 0.0065 | |
| GSE45670 | MOGAT3 | 346606 | 234850_at | 0.0483 | 0.5828 | |
| GSE53622 | MOGAT3 | 346606 | 4836 | 0.1151 | 0.1656 | |
| GSE53624 | MOGAT3 | 346606 | 4836 | -0.2442 | 0.0013 | |
| GSE63941 | MOGAT3 | 346606 | 234850_at | 0.0447 | 0.7038 | |
| GSE77861 | MOGAT3 | 346606 | 234850_at | 0.0239 | 0.8748 | |
| GSE97050 | MOGAT3 | 346606 | A_23_P317796 | -0.1247 | 0.5268 | |
| SRP064894 | MOGAT3 | 346606 | RNAseq | -1.4659 | 0.0000 | |
| SRP133303 | MOGAT3 | 346606 | RNAseq | -0.7746 | 0.0000 | |
| SRP159526 | MOGAT3 | 346606 | RNAseq | -1.4657 | 0.0035 | |
| SRP193095 | MOGAT3 | 346606 | RNAseq | -0.8856 | 0.0000 | |
| SRP219564 | MOGAT3 | 346606 | RNAseq | -1.7242 | 0.0064 | |
| TCGA | MOGAT3 | 346606 | RNAseq | -0.2349 | 0.8704 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by MOGAT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOGAT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOGAT3 | 346606 | 13 | 0 | 17 | |
| GSE20123 | MOGAT3 | 346606 | 13 | 0 | 17 | |
| GSE43470 | MOGAT3 | 346606 | 7 | 2 | 34 | |
| GSE46452 | MOGAT3 | 346606 | 11 | 1 | 47 | |
| GSE47630 | MOGAT3 | 346606 | 7 | 3 | 30 | |
| GSE54993 | MOGAT3 | 346606 | 1 | 10 | 59 | |
| GSE54994 | MOGAT3 | 346606 | 15 | 3 | 35 | |
| GSE60625 | MOGAT3 | 346606 | 0 | 0 | 11 | |
| GSE74703 | MOGAT3 | 346606 | 7 | 1 | 28 | |
| GSE74704 | MOGAT3 | 346606 | 9 | 0 | 11 | |
| TCGA | MOGAT3 | 346606 | 53 | 6 | 37 |
Total number of gains: 136; Total number of losses: 26; Total Number of normals: 326.
Somatic mutations of MOGAT3:
Generating mutation plots.
Highly correlated genes for MOGAT3:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOGAT3 | OR10H1 | 0.773483 | 3 | 0 | 3 |
| MOGAT3 | HOXB9 | 0.763539 | 4 | 0 | 4 |
| MOGAT3 | PKD2L1 | 0.738877 | 3 | 0 | 3 |
| MOGAT3 | TRIM17 | 0.733134 | 3 | 0 | 3 |
| MOGAT3 | BEAN1 | 0.732954 | 3 | 0 | 3 |
| MOGAT3 | SHC2 | 0.722394 | 3 | 0 | 3 |
| MOGAT3 | PPP1R14D | 0.717888 | 3 | 0 | 3 |
| MOGAT3 | CRYGN | 0.717858 | 3 | 0 | 3 |
| MOGAT3 | RCOR2 | 0.716184 | 4 | 0 | 3 |
| MOGAT3 | SORCS3 | 0.715873 | 3 | 0 | 3 |
| MOGAT3 | FAM170B-AS1 | 0.707661 | 3 | 0 | 3 |
| MOGAT3 | PIGQ | 0.702529 | 3 | 0 | 3 |
| MOGAT3 | RPP25 | 0.697278 | 3 | 0 | 3 |
| MOGAT3 | ARHGDIG | 0.695371 | 3 | 0 | 3 |
| MOGAT3 | NLGN2 | 0.694653 | 4 | 0 | 4 |
| MOGAT3 | PRKAR1B | 0.68768 | 3 | 0 | 3 |
| MOGAT3 | NPPC | 0.687386 | 3 | 0 | 3 |
| MOGAT3 | FGF18 | 0.685992 | 3 | 0 | 3 |
| MOGAT3 | AGAP2 | 0.683115 | 3 | 0 | 3 |
| MOGAT3 | OR10C1 | 0.68295 | 4 | 0 | 3 |
For details and further investigation, click here
