| Full name: chemerin chemokine-like receptor 1 | Alias Symbol: RVER1 | ||
| Type: protein-coding gene | Cytoband: 12q23.3 | ||
| Entrez ID: 1240 | HGNC ID: HGNC:2121 | Ensembl Gene: ENSG00000174600 | OMIM ID: 602351 |
| Drug and gene relationship at DGIdb | |||
Expression of CMKLR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CMKLR1 | 1240 | 229121_at | 0.0561 | 0.9204 | |
| GSE20347 | CMKLR1 | 1240 | 207652_s_at | 0.1721 | 0.0289 | |
| GSE23400 | CMKLR1 | 1240 | 207652_s_at | -0.1213 | 0.0003 | |
| GSE26886 | CMKLR1 | 1240 | 229121_at | 0.0597 | 0.7045 | |
| GSE29001 | CMKLR1 | 1240 | 207652_s_at | -0.0492 | 0.8275 | |
| GSE38129 | CMKLR1 | 1240 | 207652_s_at | 0.0019 | 0.9833 | |
| GSE45670 | CMKLR1 | 1240 | 229121_at | -0.3281 | 0.1524 | |
| GSE53622 | CMKLR1 | 1240 | 10406 | -0.0915 | 0.5379 | |
| GSE53624 | CMKLR1 | 1240 | 10406 | 0.1302 | 0.3663 | |
| GSE63941 | CMKLR1 | 1240 | 229121_at | -1.3522 | 0.0001 | |
| GSE77861 | CMKLR1 | 1240 | 229121_at | -0.0489 | 0.6790 | |
| GSE97050 | CMKLR1 | 1240 | A_24_P766716 | 0.0879 | 0.7561 | |
| SRP007169 | CMKLR1 | 1240 | RNAseq | 2.8146 | 0.0012 | |
| SRP008496 | CMKLR1 | 1240 | RNAseq | 2.4176 | 0.0001 | |
| SRP064894 | CMKLR1 | 1240 | RNAseq | 0.9428 | 0.0258 | |
| SRP133303 | CMKLR1 | 1240 | RNAseq | 0.2836 | 0.4284 | |
| SRP159526 | CMKLR1 | 1240 | RNAseq | 0.4926 | 0.5416 | |
| SRP193095 | CMKLR1 | 1240 | RNAseq | 0.9246 | 0.0011 | |
| SRP219564 | CMKLR1 | 1240 | RNAseq | 0.8435 | 0.2397 | |
| TCGA | CMKLR1 | 1240 | RNAseq | -0.0919 | 0.5803 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by CMKLR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CMKLR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CMKLR1 | 1240 | 5 | 3 | 22 | |
| GSE20123 | CMKLR1 | 1240 | 5 | 3 | 22 | |
| GSE43470 | CMKLR1 | 1240 | 2 | 1 | 40 | |
| GSE46452 | CMKLR1 | 1240 | 9 | 1 | 49 | |
| GSE47630 | CMKLR1 | 1240 | 9 | 1 | 30 | |
| GSE54993 | CMKLR1 | 1240 | 0 | 5 | 65 | |
| GSE54994 | CMKLR1 | 1240 | 4 | 2 | 47 | |
| GSE60625 | CMKLR1 | 1240 | 0 | 0 | 11 | |
| GSE74703 | CMKLR1 | 1240 | 2 | 0 | 34 | |
| GSE74704 | CMKLR1 | 1240 | 2 | 2 | 16 | |
| TCGA | CMKLR1 | 1240 | 21 | 10 | 65 |
Total number of gains: 59; Total number of losses: 28; Total Number of normals: 401.
Somatic mutations of CMKLR1:
Generating mutation plots.
Highly correlated genes for CMKLR1:
Showing top 20/594 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CMKLR1 | MS4A7 | 0.902408 | 3 | 0 | 3 |
| CMKLR1 | MS4A4A | 0.759442 | 6 | 0 | 5 |
| CMKLR1 | GIMAP5 | 0.747402 | 3 | 0 | 3 |
| CMKLR1 | C1QA | 0.738138 | 7 | 0 | 6 |
| CMKLR1 | CD163 | 0.730158 | 6 | 0 | 5 |
| CMKLR1 | NRROS | 0.725224 | 4 | 0 | 4 |
| CMKLR1 | CCL3 | 0.717664 | 3 | 0 | 3 |
| CMKLR1 | VSIG4 | 0.715244 | 7 | 0 | 5 |
| CMKLR1 | FCGR2B | 0.713651 | 5 | 0 | 5 |
| CMKLR1 | GIMAP4 | 0.711749 | 6 | 0 | 6 |
| CMKLR1 | SST | 0.711413 | 4 | 0 | 4 |
| CMKLR1 | TNFSF8 | 0.703472 | 7 | 0 | 6 |
| CMKLR1 | C1orf162 | 0.703134 | 6 | 0 | 6 |
| CMKLR1 | TRPV2 | 0.700261 | 7 | 0 | 7 |
| CMKLR1 | MPEG1 | 0.697 | 7 | 0 | 5 |
| CMKLR1 | FPR3 | 0.687393 | 8 | 0 | 7 |
| CMKLR1 | GMFG | 0.685534 | 7 | 0 | 6 |
| CMKLR1 | PIP4K2A | 0.680455 | 4 | 0 | 4 |
| CMKLR1 | IL10RA | 0.679309 | 6 | 0 | 5 |
| CMKLR1 | C1QC | 0.6788 | 7 | 0 | 7 |
For details and further investigation, click here
