| Full name: MAX dimerization protein 3 | Alias Symbol: MAD3|bHLHc13 | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 83463 | HGNC ID: HGNC:14008 | Ensembl Gene: ENSG00000213347 | OMIM ID: 609450 |
| Drug and gene relationship at DGIdb | |||
Expression of MXD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MXD3 | 83463 | 221250_s_at | -0.0055 | 0.9921 | |
| GSE20347 | MXD3 | 83463 | 221250_s_at | -0.0669 | 0.4912 | |
| GSE23400 | MXD3 | 83463 | 221250_s_at | -0.0693 | 0.1111 | |
| GSE26886 | MXD3 | 83463 | 221250_s_at | 0.2732 | 0.0620 | |
| GSE29001 | MXD3 | 83463 | 221250_s_at | -0.3121 | 0.0915 | |
| GSE38129 | MXD3 | 83463 | 221250_s_at | -0.0031 | 0.9771 | |
| GSE45670 | MXD3 | 83463 | 221250_s_at | -0.0559 | 0.6046 | |
| GSE53622 | MXD3 | 83463 | 41212 | 0.2286 | 0.0023 | |
| GSE53624 | MXD3 | 83463 | 41212 | 0.2925 | 0.0001 | |
| GSE63941 | MXD3 | 83463 | 221250_s_at | 0.6041 | 0.0119 | |
| GSE77861 | MXD3 | 83463 | 221250_s_at | -0.1018 | 0.4730 | |
| GSE97050 | MXD3 | 83463 | A_33_P3297255 | 0.3354 | 0.2264 | |
| SRP007169 | MXD3 | 83463 | RNAseq | -0.6448 | 0.2694 | |
| SRP064894 | MXD3 | 83463 | RNAseq | 0.5839 | 0.0721 | |
| SRP133303 | MXD3 | 83463 | RNAseq | -0.3294 | 0.1252 | |
| SRP159526 | MXD3 | 83463 | RNAseq | 0.2066 | 0.6773 | |
| SRP193095 | MXD3 | 83463 | RNAseq | 0.1173 | 0.2960 | |
| SRP219564 | MXD3 | 83463 | RNAseq | 0.0855 | 0.8392 | |
| TCGA | MXD3 | 83463 | RNAseq | 0.2021 | 0.0156 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MXD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MXD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MXD3 | 83463 | 2 | 13 | 15 | |
| GSE20123 | MXD3 | 83463 | 2 | 13 | 15 | |
| GSE43470 | MXD3 | 83463 | 1 | 11 | 31 | |
| GSE46452 | MXD3 | 83463 | 0 | 27 | 32 | |
| GSE47630 | MXD3 | 83463 | 1 | 20 | 19 | |
| GSE54993 | MXD3 | 83463 | 10 | 2 | 58 | |
| GSE54994 | MXD3 | 83463 | 2 | 17 | 34 | |
| GSE60625 | MXD3 | 83463 | 1 | 0 | 10 | |
| GSE74703 | MXD3 | 83463 | 1 | 7 | 28 | |
| GSE74704 | MXD3 | 83463 | 1 | 6 | 13 | |
| TCGA | MXD3 | 83463 | 8 | 35 | 53 |
Total number of gains: 29; Total number of losses: 151; Total Number of normals: 308.
Somatic mutations of MXD3:
Generating mutation plots.
Highly correlated genes for MXD3:
Showing top 20/480 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MXD3 | MINK1 | 0.796078 | 3 | 0 | 3 |
| MXD3 | SELP | 0.777936 | 3 | 0 | 3 |
| MXD3 | ABHD14B | 0.760259 | 3 | 0 | 3 |
| MXD3 | POLR2A | 0.751295 | 4 | 0 | 4 |
| MXD3 | NPFFR1 | 0.727627 | 3 | 0 | 3 |
| MXD3 | ETS1 | 0.726796 | 3 | 0 | 3 |
| MXD3 | KCNK2 | 0.724571 | 3 | 0 | 3 |
| MXD3 | RNFT2 | 0.723854 | 3 | 0 | 3 |
| MXD3 | TTLL1 | 0.72369 | 3 | 0 | 3 |
| MXD3 | ELMOD3 | 0.714249 | 3 | 0 | 3 |
| MXD3 | ZC3H3 | 0.709269 | 5 | 0 | 5 |
| MXD3 | ZNF76 | 0.709201 | 4 | 0 | 3 |
| MXD3 | ZNF142 | 0.705173 | 3 | 0 | 3 |
| MXD3 | CCDC97 | 0.703853 | 3 | 0 | 3 |
| MXD3 | TRAPPC1 | 0.702268 | 4 | 0 | 4 |
| MXD3 | RABEP2 | 0.692107 | 6 | 0 | 5 |
| MXD3 | DNAH11 | 0.691968 | 3 | 0 | 3 |
| MXD3 | SIN3A | 0.691042 | 3 | 0 | 3 |
| MXD3 | SLC39A3 | 0.690511 | 3 | 0 | 3 |
| MXD3 | DMBT1 | 0.686244 | 4 | 0 | 3 |
For details and further investigation, click here
