| Full name: macrophage migration inhibitory factor | Alias Symbol: GIF | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 4282 | HGNC ID: HGNC:7097 | Ensembl Gene: ENSG00000240972 | OMIM ID: 153620 |
| Drug and gene relationship at DGIdb | |||
Expression of MIF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MIF | 4282 | 217871_s_at | 0.4664 | 0.1339 | |
| GSE20347 | MIF | 4282 | 217871_s_at | -0.1289 | 0.5067 | |
| GSE23400 | MIF | 4282 | 217871_s_at | 0.1791 | 0.1038 | |
| GSE26886 | MIF | 4282 | 217871_s_at | -0.2640 | 0.4519 | |
| GSE29001 | MIF | 4282 | 217871_s_at | -0.4229 | 0.3616 | |
| GSE38129 | MIF | 4282 | 217871_s_at | 0.3357 | 0.0838 | |
| GSE45670 | MIF | 4282 | 217871_s_at | -0.1316 | 0.3758 | |
| GSE63941 | MIF | 4282 | 217871_s_at | 0.9780 | 0.0249 | |
| GSE77861 | MIF | 4282 | 217871_s_at | 0.1524 | 0.5962 | |
| GSE97050 | MIF | 4282 | A_23_P91619 | 0.1346 | 0.6010 | |
| SRP007169 | MIF | 4282 | RNAseq | -0.9331 | 0.0849 | |
| SRP008496 | MIF | 4282 | RNAseq | -0.8146 | 0.0121 | |
| SRP064894 | MIF | 4282 | RNAseq | 0.7725 | 0.0589 | |
| SRP133303 | MIF | 4282 | RNAseq | 0.1502 | 0.4889 | |
| SRP159526 | MIF | 4282 | RNAseq | 0.3690 | 0.2631 | |
| SRP193095 | MIF | 4282 | RNAseq | -0.1460 | 0.5684 | |
| SRP219564 | MIF | 4282 | RNAseq | 0.6542 | 0.0991 | |
| TCGA | MIF | 4282 | RNAseq | 0.3253 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MIF expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MIF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MIF | 4282 | 5 | 7 | 18 | |
| GSE20123 | MIF | 4282 | 5 | 6 | 19 | |
| GSE43470 | MIF | 4282 | 3 | 6 | 34 | |
| GSE46452 | MIF | 4282 | 32 | 1 | 26 | |
| GSE47630 | MIF | 4282 | 8 | 5 | 27 | |
| GSE54993 | MIF | 4282 | 3 | 6 | 61 | |
| GSE54994 | MIF | 4282 | 11 | 7 | 35 | |
| GSE60625 | MIF | 4282 | 5 | 0 | 6 | |
| GSE74703 | MIF | 4282 | 3 | 5 | 28 | |
| GSE74704 | MIF | 4282 | 2 | 3 | 15 | |
| TCGA | MIF | 4282 | 26 | 15 | 55 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of MIF:
Generating mutation plots.
Highly correlated genes for MIF:
Showing top 20/522 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MIF | INTS1 | 0.822074 | 3 | 0 | 3 |
| MIF | BCAS4 | 0.771256 | 3 | 0 | 3 |
| MIF | BLM | 0.765935 | 3 | 0 | 3 |
| MIF | MIS18A | 0.760166 | 3 | 0 | 3 |
| MIF | ZNF683 | 0.758703 | 3 | 0 | 3 |
| MIF | MYPOP | 0.748713 | 3 | 0 | 3 |
| MIF | MSH2 | 0.744926 | 3 | 0 | 3 |
| MIF | RHBDD2 | 0.744264 | 3 | 0 | 3 |
| MIF | DDX54 | 0.744022 | 3 | 0 | 3 |
| MIF | MCM3 | 0.741155 | 3 | 0 | 3 |
| MIF | SPTAN1 | 0.738636 | 3 | 0 | 3 |
| MIF | FPGS | 0.736557 | 3 | 0 | 3 |
| MIF | NFAM1 | 0.734502 | 3 | 0 | 3 |
| MIF | FIBCD1 | 0.731441 | 3 | 0 | 3 |
| MIF | MMP15 | 0.726464 | 3 | 0 | 3 |
| MIF | REL | 0.724914 | 3 | 0 | 3 |
| MIF | ARHGEF19 | 0.72204 | 4 | 0 | 4 |
| MIF | HNRNPF | 0.719962 | 3 | 0 | 3 |
| MIF | EWSR1 | 0.719241 | 3 | 0 | 3 |
| MIF | KDF1 | 0.717204 | 3 | 0 | 3 |
For details and further investigation, click here
