| Full name: angel homolog 1 | Alias Symbol: Ccr4e | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 23357 | HGNC ID: HGNC:19961 | Ensembl Gene: ENSG00000013523 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ANGEL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANGEL1 | 23357 | 213099_at | 0.3977 | 0.2189 | |
| GSE20347 | ANGEL1 | 23357 | 213099_at | 0.3957 | 0.0004 | |
| GSE23400 | ANGEL1 | 23357 | 213099_at | 0.2612 | 0.0000 | |
| GSE26886 | ANGEL1 | 23357 | 213099_at | 0.5252 | 0.0001 | |
| GSE29001 | ANGEL1 | 23357 | 213099_at | 0.4703 | 0.0057 | |
| GSE38129 | ANGEL1 | 23357 | 213099_at | 0.3885 | 0.0001 | |
| GSE45670 | ANGEL1 | 23357 | 213099_at | 0.3546 | 0.0117 | |
| GSE53622 | ANGEL1 | 23357 | 130177 | 1.0460 | 0.0000 | |
| GSE53624 | ANGEL1 | 23357 | 130177 | 1.1190 | 0.0000 | |
| GSE63941 | ANGEL1 | 23357 | 213099_at | 0.6474 | 0.0235 | |
| GSE77861 | ANGEL1 | 23357 | 36865_at | 0.0268 | 0.8594 | |
| GSE97050 | ANGEL1 | 23357 | A_23_P363406 | 0.4050 | 0.2781 | |
| SRP007169 | ANGEL1 | 23357 | RNAseq | 1.2748 | 0.0156 | |
| SRP008496 | ANGEL1 | 23357 | RNAseq | 1.2767 | 0.0022 | |
| SRP064894 | ANGEL1 | 23357 | RNAseq | 0.8621 | 0.0000 | |
| SRP133303 | ANGEL1 | 23357 | RNAseq | 0.5223 | 0.0088 | |
| SRP159526 | ANGEL1 | 23357 | RNAseq | 0.5807 | 0.0513 | |
| SRP193095 | ANGEL1 | 23357 | RNAseq | 0.5111 | 0.0000 | |
| SRP219564 | ANGEL1 | 23357 | RNAseq | 0.8555 | 0.0023 | |
| TCGA | ANGEL1 | 23357 | RNAseq | -0.0898 | 0.0939 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by ANGEL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANGEL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANGEL1 | 23357 | 8 | 3 | 19 | |
| GSE20123 | ANGEL1 | 23357 | 8 | 3 | 19 | |
| GSE43470 | ANGEL1 | 23357 | 8 | 3 | 32 | |
| GSE46452 | ANGEL1 | 23357 | 16 | 3 | 40 | |
| GSE47630 | ANGEL1 | 23357 | 11 | 8 | 21 | |
| GSE54993 | ANGEL1 | 23357 | 3 | 8 | 59 | |
| GSE54994 | ANGEL1 | 23357 | 19 | 4 | 30 | |
| GSE60625 | ANGEL1 | 23357 | 0 | 2 | 9 | |
| GSE74703 | ANGEL1 | 23357 | 7 | 3 | 26 | |
| GSE74704 | ANGEL1 | 23357 | 3 | 3 | 14 | |
| TCGA | ANGEL1 | 23357 | 32 | 17 | 47 |
Total number of gains: 115; Total number of losses: 57; Total Number of normals: 316.
Somatic mutations of ANGEL1:
Generating mutation plots.
Highly correlated genes for ANGEL1:
Showing top 20/1366 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANGEL1 | NEIL2 | 0.732394 | 3 | 0 | 3 |
| ANGEL1 | ZNF707 | 0.730074 | 3 | 0 | 3 |
| ANGEL1 | SLC7A6OS | 0.718661 | 3 | 0 | 3 |
| ANGEL1 | SLC35B2 | 0.711293 | 3 | 0 | 3 |
| ANGEL1 | IFT43 | 0.709942 | 7 | 0 | 7 |
| ANGEL1 | SNAP47 | 0.700671 | 3 | 0 | 3 |
| ANGEL1 | FAM89A | 0.700192 | 3 | 0 | 3 |
| ANGEL1 | MED24 | 0.696105 | 3 | 0 | 3 |
| ANGEL1 | TATDN1 | 0.694544 | 6 | 0 | 5 |
| ANGEL1 | ZDHHC16 | 0.690946 | 4 | 0 | 4 |
| ANGEL1 | MGAT2 | 0.688791 | 4 | 0 | 3 |
| ANGEL1 | MRPS23 | 0.683863 | 7 | 0 | 6 |
| ANGEL1 | WDR54 | 0.68372 | 7 | 0 | 7 |
| ANGEL1 | BOLA3 | 0.683327 | 6 | 0 | 6 |
| ANGEL1 | NUDCD1 | 0.680144 | 6 | 0 | 6 |
| ANGEL1 | LRRC8E | 0.674404 | 3 | 0 | 3 |
| ANGEL1 | DKC1 | 0.671615 | 3 | 0 | 3 |
| ANGEL1 | GNG10 | 0.671027 | 3 | 0 | 3 |
| ANGEL1 | SLC5A2 | 0.670935 | 3 | 0 | 3 |
| ANGEL1 | C16orf74 | 0.670904 | 6 | 0 | 6 |
For details and further investigation, click here
