| Full name: mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | Alias Symbol: GNT-II | ||
| Type: protein-coding gene | Cytoband: 14q21.3 | ||
| Entrez ID: 4247 | HGNC ID: HGNC:7045 | Ensembl Gene: ENSG00000168282 | OMIM ID: 602616 |
| Drug and gene relationship at DGIdb | |||
Expression of MGAT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MGAT2 | 4247 | 203102_s_at | 1.0538 | 0.2006 | |
| GSE20347 | MGAT2 | 4247 | 203102_s_at | 0.2834 | 0.1014 | |
| GSE23400 | MGAT2 | 4247 | 211061_s_at | 0.4118 | 0.0000 | |
| GSE26886 | MGAT2 | 4247 | 211061_s_at | -0.0858 | 0.7808 | |
| GSE29001 | MGAT2 | 4247 | 211061_s_at | 0.0342 | 0.9020 | |
| GSE38129 | MGAT2 | 4247 | 203102_s_at | 0.4977 | 0.0001 | |
| GSE45670 | MGAT2 | 4247 | 203102_s_at | 0.6016 | 0.0004 | |
| GSE63941 | MGAT2 | 4247 | 203102_s_at | -0.6014 | 0.1961 | |
| GSE77861 | MGAT2 | 4247 | 203102_s_at | 0.3018 | 0.4450 | |
| GSE97050 | MGAT2 | 4247 | A_23_P65558 | 0.7227 | 0.1074 | |
| SRP007169 | MGAT2 | 4247 | RNAseq | 0.1971 | 0.5732 | |
| SRP008496 | MGAT2 | 4247 | RNAseq | 0.6430 | 0.0059 | |
| SRP064894 | MGAT2 | 4247 | RNAseq | 0.7362 | 0.0000 | |
| SRP133303 | MGAT2 | 4247 | RNAseq | 0.6846 | 0.0000 | |
| SRP159526 | MGAT2 | 4247 | RNAseq | 0.3272 | 0.2412 | |
| SRP193095 | MGAT2 | 4247 | RNAseq | 0.1364 | 0.4706 | |
| SRP219564 | MGAT2 | 4247 | RNAseq | 0.8956 | 0.0673 | |
| TCGA | MGAT2 | 4247 | RNAseq | 0.0792 | 0.1240 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MGAT2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MGAT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MGAT2 | 4247 | 7 | 2 | 21 | |
| GSE20123 | MGAT2 | 4247 | 7 | 3 | 20 | |
| GSE43470 | MGAT2 | 4247 | 9 | 1 | 33 | |
| GSE46452 | MGAT2 | 4247 | 16 | 3 | 40 | |
| GSE47630 | MGAT2 | 4247 | 11 | 10 | 19 | |
| GSE54993 | MGAT2 | 4247 | 3 | 9 | 58 | |
| GSE54994 | MGAT2 | 4247 | 19 | 4 | 30 | |
| GSE60625 | MGAT2 | 4247 | 0 | 2 | 9 | |
| GSE74703 | MGAT2 | 4247 | 7 | 1 | 28 | |
| GSE74704 | MGAT2 | 4247 | 2 | 2 | 16 | |
| TCGA | MGAT2 | 4247 | 33 | 13 | 50 |
Total number of gains: 114; Total number of losses: 50; Total Number of normals: 324.
Somatic mutations of MGAT2:
Generating mutation plots.
Highly correlated genes for MGAT2:
Showing top 20/951 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MGAT2 | CLSPN | 0.807364 | 3 | 0 | 3 |
| MGAT2 | MZT1 | 0.788458 | 3 | 0 | 3 |
| MGAT2 | MASTL | 0.785361 | 3 | 0 | 3 |
| MGAT2 | DNAAF2 | 0.781807 | 7 | 0 | 7 |
| MGAT2 | PSMG3 | 0.769891 | 3 | 0 | 3 |
| MGAT2 | CYP27C1 | 0.765397 | 4 | 0 | 4 |
| MGAT2 | GEN1 | 0.75936 | 3 | 0 | 3 |
| MGAT2 | UBTD2 | 0.755371 | 4 | 0 | 3 |
| MGAT2 | INTS10 | 0.754396 | 3 | 0 | 3 |
| MGAT2 | JKAMP | 0.754338 | 6 | 0 | 6 |
| MGAT2 | TMEM117 | 0.750806 | 3 | 0 | 3 |
| MGAT2 | JAK1 | 0.746703 | 3 | 0 | 3 |
| MGAT2 | TPCN2 | 0.746303 | 3 | 0 | 3 |
| MGAT2 | ISCA2 | 0.740906 | 6 | 0 | 6 |
| MGAT2 | WDR54 | 0.740216 | 3 | 0 | 3 |
| MGAT2 | SPATA5 | 0.738174 | 3 | 0 | 3 |
| MGAT2 | FANCM | 0.736388 | 4 | 0 | 4 |
| MGAT2 | IRF2BPL | 0.736139 | 3 | 0 | 3 |
| MGAT2 | CENPL | 0.736025 | 4 | 0 | 3 |
| MGAT2 | C8orf76 | 0.735138 | 3 | 0 | 3 |
For details and further investigation, click here
