| Full name: bolA family member 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 388962 | HGNC ID: HGNC:24415 | Ensembl Gene: ENSG00000163170 | OMIM ID: 613183 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of BOLA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BOLA3 | 388962 | 227291_s_at | 0.5431 | 0.1009 | |
| GSE26886 | BOLA3 | 388962 | 227291_s_at | 0.9792 | 0.0001 | |
| GSE45670 | BOLA3 | 388962 | 227291_s_at | 0.6643 | 0.0003 | |
| GSE53622 | BOLA3 | 388962 | 41680 | 0.6830 | 0.0000 | |
| GSE53624 | BOLA3 | 388962 | 41680 | 1.0442 | 0.0000 | |
| GSE63941 | BOLA3 | 388962 | 227291_s_at | 0.0818 | 0.9217 | |
| GSE77861 | BOLA3 | 388962 | 227291_s_at | 0.7742 | 0.0181 | |
| GSE97050 | BOLA3 | 388962 | A_24_P77364 | 0.5469 | 0.1856 | |
| SRP007169 | BOLA3 | 388962 | RNAseq | 1.6649 | 0.0001 | |
| SRP008496 | BOLA3 | 388962 | RNAseq | 1.3530 | 0.0001 | |
| SRP064894 | BOLA3 | 388962 | RNAseq | 0.7432 | 0.0073 | |
| SRP133303 | BOLA3 | 388962 | RNAseq | 1.0485 | 0.0000 | |
| SRP159526 | BOLA3 | 388962 | RNAseq | 1.2297 | 0.0002 | |
| SRP193095 | BOLA3 | 388962 | RNAseq | 0.2493 | 0.2216 | |
| SRP219564 | BOLA3 | 388962 | RNAseq | 0.5731 | 0.2360 | |
| TCGA | BOLA3 | 388962 | RNAseq | 0.1619 | 0.0531 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by BOLA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BOLA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BOLA3 | 388962 | 10 | 1 | 19 | |
| GSE20123 | BOLA3 | 388962 | 11 | 1 | 18 | |
| GSE43470 | BOLA3 | 388962 | 4 | 0 | 39 | |
| GSE46452 | BOLA3 | 388962 | 2 | 3 | 54 | |
| GSE47630 | BOLA3 | 388962 | 7 | 0 | 33 | |
| GSE54993 | BOLA3 | 388962 | 0 | 6 | 64 | |
| GSE54994 | BOLA3 | 388962 | 10 | 0 | 43 | |
| GSE60625 | BOLA3 | 388962 | 0 | 3 | 8 | |
| GSE74703 | BOLA3 | 388962 | 4 | 0 | 32 | |
| GSE74704 | BOLA3 | 388962 | 8 | 0 | 12 | |
| TCGA | BOLA3 | 388962 | 38 | 2 | 56 |
Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.
Somatic mutations of BOLA3:
Generating mutation plots.
Highly correlated genes for BOLA3:
Showing top 20/2121 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BOLA3 | PYCR2 | 0.812372 | 3 | 0 | 3 |
| BOLA3 | C11orf24 | 0.79643 | 7 | 0 | 7 |
| BOLA3 | TDP1 | 0.791942 | 3 | 0 | 3 |
| BOLA3 | KNSTRN | 0.790408 | 6 | 0 | 6 |
| BOLA3 | EBNA1BP2 | 0.789731 | 3 | 0 | 3 |
| BOLA3 | STC2 | 0.787212 | 6 | 0 | 6 |
| BOLA3 | PTRH2 | 0.786717 | 7 | 0 | 7 |
| BOLA3 | PFDN2 | 0.778676 | 7 | 0 | 7 |
| BOLA3 | FHL3 | 0.778494 | 3 | 0 | 3 |
| BOLA3 | CMSS1 | 0.764761 | 6 | 0 | 6 |
| BOLA3 | PLXNA1 | 0.753682 | 7 | 0 | 7 |
| BOLA3 | NUDT1 | 0.751193 | 7 | 0 | 7 |
| BOLA3 | HJURP | 0.750878 | 6 | 0 | 6 |
| BOLA3 | CCT6A | 0.749661 | 4 | 0 | 4 |
| BOLA3 | MRPS17 | 0.749552 | 4 | 0 | 4 |
| BOLA3 | DDX39A | 0.749536 | 7 | 0 | 7 |
| BOLA3 | U2SURP | 0.749243 | 5 | 0 | 5 |
| BOLA3 | MRPL47 | 0.748936 | 8 | 0 | 7 |
| BOLA3 | UBE2C | 0.747231 | 7 | 0 | 7 |
| BOLA3 | TMEM184B | 0.745628 | 7 | 0 | 7 |
For details and further investigation, click here
