| Full name: zinc finger DHHC-type containing 16 | Alias Symbol: APH2 | ||
| Type: protein-coding gene | Cytoband: 10q24.1 | ||
| Entrez ID: 84287 | HGNC ID: HGNC:20714 | Ensembl Gene: ENSG00000171307 | OMIM ID: 616750 |
| Drug and gene relationship at DGIdb | |||
Expression of ZDHHC16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZDHHC16 | 84287 | 223212_at | 0.4365 | 0.1411 | |
| GSE26886 | ZDHHC16 | 84287 | 223212_at | 0.5016 | 0.0015 | |
| GSE45670 | ZDHHC16 | 84287 | 223212_at | 0.6118 | 0.0000 | |
| GSE53622 | ZDHHC16 | 84287 | 104904 | 0.5720 | 0.0000 | |
| GSE53624 | ZDHHC16 | 84287 | 104904 | 0.6111 | 0.0000 | |
| GSE63941 | ZDHHC16 | 84287 | 223212_at | -0.1540 | 0.6546 | |
| GSE77861 | ZDHHC16 | 84287 | 223212_at | 0.1641 | 0.5797 | |
| GSE97050 | ZDHHC16 | 84287 | A_23_P150009 | 0.6287 | 0.1316 | |
| SRP007169 | ZDHHC16 | 84287 | RNAseq | -0.0912 | 0.8253 | |
| SRP008496 | ZDHHC16 | 84287 | RNAseq | 0.1858 | 0.4882 | |
| SRP064894 | ZDHHC16 | 84287 | RNAseq | 0.6304 | 0.0049 | |
| SRP133303 | ZDHHC16 | 84287 | RNAseq | 0.3616 | 0.0367 | |
| SRP159526 | ZDHHC16 | 84287 | RNAseq | 0.4514 | 0.0567 | |
| SRP193095 | ZDHHC16 | 84287 | RNAseq | 0.3263 | 0.0002 | |
| SRP219564 | ZDHHC16 | 84287 | RNAseq | 0.4160 | 0.0998 | |
| TCGA | ZDHHC16 | 84287 | RNAseq | 0.0074 | 0.8933 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZDHHC16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZDHHC16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZDHHC16 | 84287 | 0 | 8 | 22 | |
| GSE20123 | ZDHHC16 | 84287 | 0 | 7 | 23 | |
| GSE43470 | ZDHHC16 | 84287 | 0 | 7 | 36 | |
| GSE46452 | ZDHHC16 | 84287 | 0 | 11 | 48 | |
| GSE47630 | ZDHHC16 | 84287 | 2 | 14 | 24 | |
| GSE54993 | ZDHHC16 | 84287 | 8 | 0 | 62 | |
| GSE54994 | ZDHHC16 | 84287 | 2 | 10 | 41 | |
| GSE60625 | ZDHHC16 | 84287 | 0 | 0 | 11 | |
| GSE74703 | ZDHHC16 | 84287 | 0 | 5 | 31 | |
| GSE74704 | ZDHHC16 | 84287 | 0 | 4 | 16 | |
| TCGA | ZDHHC16 | 84287 | 5 | 28 | 63 |
Total number of gains: 17; Total number of losses: 94; Total Number of normals: 377.
Somatic mutations of ZDHHC16:
Generating mutation plots.
Highly correlated genes for ZDHHC16:
Showing top 20/1758 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZDHHC16 | DNAJC9 | 0.861844 | 4 | 0 | 4 |
| ZDHHC16 | INTS10 | 0.820221 | 3 | 0 | 3 |
| ZDHHC16 | RAD18 | 0.795202 | 3 | 0 | 3 |
| ZDHHC16 | MTHFD1L | 0.78737 | 3 | 0 | 3 |
| ZDHHC16 | RPN1 | 0.775306 | 5 | 0 | 5 |
| ZDHHC16 | CEP55 | 0.773911 | 6 | 0 | 6 |
| ZDHHC16 | RALGAPB | 0.772769 | 3 | 0 | 3 |
| ZDHHC16 | CCNF | 0.764662 | 6 | 0 | 6 |
| ZDHHC16 | KIF23 | 0.761911 | 6 | 0 | 6 |
| ZDHHC16 | ACTL6A | 0.760962 | 6 | 0 | 6 |
| ZDHHC16 | RPP38 | 0.756858 | 4 | 0 | 4 |
| ZDHHC16 | XPO1 | 0.754924 | 6 | 0 | 6 |
| ZDHHC16 | BRCA1 | 0.752928 | 6 | 0 | 6 |
| ZDHHC16 | MAZ | 0.749528 | 4 | 0 | 3 |
| ZDHHC16 | PRDM15 | 0.748579 | 3 | 0 | 3 |
| ZDHHC16 | POLA2 | 0.745334 | 6 | 0 | 6 |
| ZDHHC16 | CLN6 | 0.74338 | 4 | 0 | 4 |
| ZDHHC16 | THOC6 | 0.741477 | 5 | 0 | 5 |
| ZDHHC16 | MRPS34 | 0.741076 | 5 | 0 | 5 |
| ZDHHC16 | RBL1 | 0.740738 | 5 | 0 | 5 |
For details and further investigation, click here
