| Full name: nei like DNA glycosylase 2 | Alias Symbol: NEH2|FLJ31644|MGC2832|MGC4505 | ||
| Type: protein-coding gene | Cytoband: 8p23.1 | ||
| Entrez ID: 252969 | HGNC ID: HGNC:18956 | Ensembl Gene: ENSG00000154328 | OMIM ID: 608933 |
| Drug and gene relationship at DGIdb | |||
Expression of NEIL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEIL2 | 252969 | 226585_at | 0.5182 | 0.1125 | |
| GSE26886 | NEIL2 | 252969 | 226585_at | 0.3130 | 0.0462 | |
| GSE45670 | NEIL2 | 252969 | 226585_at | 0.3823 | 0.0352 | |
| GSE63941 | NEIL2 | 252969 | 226585_at | -0.6963 | 0.0983 | |
| GSE77861 | NEIL2 | 252969 | 226585_at | 0.2003 | 0.4362 | |
| GSE97050 | NEIL2 | 252969 | A_23_P94128 | 0.1468 | 0.5982 | |
| SRP007169 | NEIL2 | 252969 | RNAseq | 1.4821 | 0.0553 | |
| SRP064894 | NEIL2 | 252969 | RNAseq | 0.5236 | 0.0440 | |
| SRP133303 | NEIL2 | 252969 | RNAseq | -0.0957 | 0.6090 | |
| SRP159526 | NEIL2 | 252969 | RNAseq | 0.3980 | 0.2150 | |
| SRP193095 | NEIL2 | 252969 | RNAseq | 0.3045 | 0.0237 | |
| SRP219564 | NEIL2 | 252969 | RNAseq | 0.2455 | 0.6597 | |
| TCGA | NEIL2 | 252969 | RNAseq | 0.0776 | 0.3180 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NEIL2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NEIL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEIL2 | 252969 | 4 | 11 | 15 | |
| GSE20123 | NEIL2 | 252969 | 4 | 11 | 15 | |
| GSE43470 | NEIL2 | 252969 | 4 | 9 | 30 | |
| GSE46452 | NEIL2 | 252969 | 12 | 14 | 33 | |
| GSE47630 | NEIL2 | 252969 | 10 | 7 | 23 | |
| GSE54993 | NEIL2 | 252969 | 3 | 14 | 53 | |
| GSE54994 | NEIL2 | 252969 | 8 | 19 | 26 | |
| GSE60625 | NEIL2 | 252969 | 3 | 0 | 8 | |
| GSE74703 | NEIL2 | 252969 | 4 | 7 | 25 | |
| GSE74704 | NEIL2 | 252969 | 3 | 7 | 10 | |
| TCGA | NEIL2 | 252969 | 14 | 39 | 43 |
Total number of gains: 69; Total number of losses: 138; Total Number of normals: 281.
Somatic mutations of NEIL2:
Generating mutation plots.
Highly correlated genes for NEIL2:
Showing top 20/650 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEIL2 | G0S2 | 0.812942 | 3 | 0 | 3 |
| NEIL2 | COX7A2L | 0.784775 | 3 | 0 | 3 |
| NEIL2 | CHST2 | 0.780316 | 3 | 0 | 3 |
| NEIL2 | APH1B | 0.765699 | 3 | 0 | 3 |
| NEIL2 | TMEM138 | 0.762558 | 3 | 0 | 3 |
| NEIL2 | DYRK3 | 0.759302 | 3 | 0 | 3 |
| NEIL2 | THOC5 | 0.756065 | 3 | 0 | 3 |
| NEIL2 | TPCN2 | 0.750107 | 3 | 0 | 3 |
| NEIL2 | STARD7 | 0.748206 | 3 | 0 | 3 |
| NEIL2 | DLX5 | 0.74759 | 3 | 0 | 3 |
| NEIL2 | HPCAL1 | 0.746753 | 3 | 0 | 3 |
| NEIL2 | RNF13 | 0.74463 | 3 | 0 | 3 |
| NEIL2 | FNTA | 0.742178 | 3 | 0 | 3 |
| NEIL2 | PRELID2 | 0.737706 | 3 | 0 | 3 |
| NEIL2 | MCM3AP | 0.734468 | 4 | 0 | 4 |
| NEIL2 | ANGEL1 | 0.732394 | 3 | 0 | 3 |
| NEIL2 | TNFRSF18 | 0.731489 | 3 | 0 | 3 |
| NEIL2 | ABCG1 | 0.728226 | 3 | 0 | 3 |
| NEIL2 | SOCS4 | 0.727948 | 3 | 0 | 3 |
| NEIL2 | SPSB4 | 0.727307 | 3 | 0 | 3 |
For details and further investigation, click here
