| Full name: ankyrin repeat domain 11 | Alias Symbol: LZ16|T13 | ||
| Type: protein-coding gene | Cytoband: 16q24.3 | ||
| Entrez ID: 29123 | HGNC ID: HGNC:21316 | Ensembl Gene: ENSG00000167522 | OMIM ID: 611192 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ANKRD11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD11 | 29123 | 238538_at | 0.1102 | 0.7676 | |
| GSE20347 | ANKRD11 | 29123 | 219437_s_at | -0.2514 | 0.0354 | |
| GSE23400 | ANKRD11 | 29123 | 219437_s_at | -0.1357 | 0.1285 | |
| GSE26886 | ANKRD11 | 29123 | 238538_at | 0.7790 | 0.0000 | |
| GSE29001 | ANKRD11 | 29123 | 219437_s_at | -0.2259 | 0.6299 | |
| GSE38129 | ANKRD11 | 29123 | 219437_s_at | -0.0429 | 0.8902 | |
| GSE45670 | ANKRD11 | 29123 | 238538_at | 0.0271 | 0.8497 | |
| GSE53622 | ANKRD11 | 29123 | 130464 | -0.2014 | 0.0000 | |
| GSE53624 | ANKRD11 | 29123 | 7766 | 0.0424 | 0.4094 | |
| GSE63941 | ANKRD11 | 29123 | 238538_at | 0.0094 | 0.9826 | |
| GSE77861 | ANKRD11 | 29123 | 238538_at | 0.4021 | 0.0863 | |
| GSE97050 | ANKRD11 | 29123 | A_33_P3280044 | -0.0305 | 0.8892 | |
| SRP007169 | ANKRD11 | 29123 | RNAseq | -0.1598 | 0.7217 | |
| SRP008496 | ANKRD11 | 29123 | RNAseq | -0.2065 | 0.5417 | |
| SRP064894 | ANKRD11 | 29123 | RNAseq | -0.3706 | 0.0170 | |
| SRP133303 | ANKRD11 | 29123 | RNAseq | 0.3387 | 0.2319 | |
| SRP159526 | ANKRD11 | 29123 | RNAseq | 0.0037 | 0.9890 | |
| SRP193095 | ANKRD11 | 29123 | RNAseq | 0.2666 | 0.0829 | |
| SRP219564 | ANKRD11 | 29123 | RNAseq | -0.4290 | 0.0738 | |
| TCGA | ANKRD11 | 29123 | RNAseq | -0.0566 | 0.1377 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKRD11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD11 | 29123 | 4 | 3 | 23 | |
| GSE20123 | ANKRD11 | 29123 | 4 | 3 | 23 | |
| GSE43470 | ANKRD11 | 29123 | 1 | 13 | 29 | |
| GSE46452 | ANKRD11 | 29123 | 38 | 1 | 20 | |
| GSE47630 | ANKRD11 | 29123 | 11 | 9 | 20 | |
| GSE54993 | ANKRD11 | 29123 | 3 | 4 | 63 | |
| GSE54994 | ANKRD11 | 29123 | 9 | 11 | 33 | |
| GSE60625 | ANKRD11 | 29123 | 4 | 0 | 7 | |
| GSE74703 | ANKRD11 | 29123 | 1 | 9 | 26 | |
| GSE74704 | ANKRD11 | 29123 | 3 | 2 | 15 | |
| TCGA | ANKRD11 | 29123 | 27 | 15 | 54 |
Total number of gains: 105; Total number of losses: 70; Total Number of normals: 313.
Somatic mutations of ANKRD11:
Generating mutation plots.
Highly correlated genes for ANKRD11:
Showing top 20/234 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD11 | XAB2 | 0.811907 | 3 | 0 | 3 |
| ANKRD11 | PSMG3 | 0.806522 | 3 | 0 | 3 |
| ANKRD11 | MEF2A | 0.778979 | 3 | 0 | 3 |
| ANKRD11 | SF3A2 | 0.76736 | 3 | 0 | 3 |
| ANKRD11 | CPSF3 | 0.764134 | 3 | 0 | 3 |
| ANKRD11 | COMMD9 | 0.760382 | 3 | 0 | 3 |
| ANKRD11 | TK2 | 0.756239 | 3 | 0 | 3 |
| ANKRD11 | TRAF7 | 0.751064 | 3 | 0 | 3 |
| ANKRD11 | C1orf131 | 0.749985 | 3 | 0 | 3 |
| ANKRD11 | C17orf75 | 0.74797 | 3 | 0 | 3 |
| ANKRD11 | RBM4 | 0.747791 | 3 | 0 | 3 |
| ANKRD11 | MRPL55 | 0.74581 | 3 | 0 | 3 |
| ANKRD11 | MRPL47 | 0.745369 | 3 | 0 | 3 |
| ANKRD11 | GAS2L1 | 0.742599 | 3 | 0 | 3 |
| ANKRD11 | MARK1 | 0.736636 | 3 | 0 | 3 |
| ANKRD11 | ROMO1 | 0.732937 | 3 | 0 | 3 |
| ANKRD11 | UTP20 | 0.731484 | 3 | 0 | 3 |
| ANKRD11 | DDX19A | 0.730958 | 3 | 0 | 3 |
| ANKRD11 | KLC1 | 0.727326 | 3 | 0 | 3 |
| ANKRD11 | RPL19 | 0.725789 | 3 | 0 | 3 |
For details and further investigation, click here
