| Full name: mitochondrial ribosomal protein L47 | Alias Symbol: CGI-204|NCM1 | ||
| Type: protein-coding gene | Cytoband: 3q26.33 | ||
| Entrez ID: 57129 | HGNC ID: HGNC:16652 | Ensembl Gene: ENSG00000136522 | OMIM ID: 611852 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL47:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL47 | 57129 | 223480_s_at | 0.7101 | 0.0480 | |
| GSE26886 | MRPL47 | 57129 | 223480_s_at | 1.8926 | 0.0000 | |
| GSE45670 | MRPL47 | 57129 | 223480_s_at | 1.0434 | 0.0000 | |
| GSE53622 | MRPL47 | 57129 | 46987 | 0.8201 | 0.0000 | |
| GSE53624 | MRPL47 | 57129 | 46987 | 1.2403 | 0.0000 | |
| GSE63941 | MRPL47 | 57129 | 223480_s_at | 1.1858 | 0.0315 | |
| GSE77861 | MRPL47 | 57129 | 223480_s_at | 0.8901 | 0.0173 | |
| GSE97050 | MRPL47 | 57129 | A_23_P502425 | 0.5348 | 0.1755 | |
| SRP007169 | MRPL47 | 57129 | RNAseq | 1.4816 | 0.0007 | |
| SRP008496 | MRPL47 | 57129 | RNAseq | 1.3071 | 0.0000 | |
| SRP064894 | MRPL47 | 57129 | RNAseq | 1.0372 | 0.0000 | |
| SRP133303 | MRPL47 | 57129 | RNAseq | 1.1775 | 0.0000 | |
| SRP159526 | MRPL47 | 57129 | RNAseq | 1.3979 | 0.0000 | |
| SRP193095 | MRPL47 | 57129 | RNAseq | 0.5442 | 0.0003 | |
| SRP219564 | MRPL47 | 57129 | RNAseq | 0.3927 | 0.3749 | |
| TCGA | MRPL47 | 57129 | RNAseq | 0.3675 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by MRPL47 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL47:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL47 | 57129 | 25 | 0 | 5 | |
| GSE20123 | MRPL47 | 57129 | 25 | 0 | 5 | |
| GSE43470 | MRPL47 | 57129 | 24 | 0 | 19 | |
| GSE46452 | MRPL47 | 57129 | 19 | 1 | 39 | |
| GSE47630 | MRPL47 | 57129 | 27 | 2 | 11 | |
| GSE54993 | MRPL47 | 57129 | 1 | 18 | 51 | |
| GSE54994 | MRPL47 | 57129 | 41 | 0 | 12 | |
| GSE60625 | MRPL47 | 57129 | 0 | 6 | 5 | |
| GSE74703 | MRPL47 | 57129 | 20 | 0 | 16 | |
| GSE74704 | MRPL47 | 57129 | 16 | 0 | 4 | |
| TCGA | MRPL47 | 57129 | 78 | 0 | 18 |
Total number of gains: 276; Total number of losses: 27; Total Number of normals: 185.
Somatic mutations of MRPL47:
Generating mutation plots.
Highly correlated genes for MRPL47:
Showing top 20/2089 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL47 | ACTL6A | 0.868207 | 9 | 0 | 9 |
| MRPL47 | FXR1 | 0.812163 | 7 | 0 | 7 |
| MRPL47 | PLXNA1 | 0.809594 | 7 | 0 | 7 |
| MRPL47 | ALG3 | 0.80864 | 7 | 0 | 7 |
| MRPL47 | GMPS | 0.790681 | 8 | 0 | 8 |
| MRPL47 | PYCR2 | 0.789476 | 3 | 0 | 3 |
| MRPL47 | CMSS1 | 0.789125 | 7 | 0 | 7 |
| MRPL47 | ALG1 | 0.787368 | 5 | 0 | 5 |
| MRPL47 | U2SURP | 0.786431 | 6 | 0 | 5 |
| MRPL47 | FHL3 | 0.786163 | 3 | 0 | 3 |
| MRPL47 | EBNA1BP2 | 0.784981 | 3 | 0 | 3 |
| MRPL47 | ABCF3 | 0.78357 | 7 | 0 | 7 |
| MRPL47 | PSMG3 | 0.78091 | 7 | 0 | 7 |
| MRPL47 | ATP13A3 | 0.778789 | 7 | 0 | 7 |
| MRPL47 | SCNM1 | 0.77822 | 3 | 0 | 3 |
| MRPL47 | PSME4 | 0.775617 | 7 | 0 | 7 |
| MRPL47 | MFHAS1 | 0.775614 | 7 | 0 | 7 |
| MRPL47 | DNAJB11 | 0.77442 | 8 | 0 | 7 |
| MRPL47 | USP39 | 0.774414 | 6 | 0 | 6 |
| MRPL47 | ZNF707 | 0.770653 | 3 | 0 | 3 |
For details and further investigation, click here
