| Full name: chromosome 17 open reading frame 75 | Alias Symbol: NJMU-R1|SRI2 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 64149 | HGNC ID: HGNC:30173 | Ensembl Gene: ENSG00000108666 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C17orf75:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C17orf75 | 64149 | 203830_at | 0.2953 | 0.4258 | |
| GSE20347 | C17orf75 | 64149 | 203830_at | 0.9285 | 0.0036 | |
| GSE23400 | C17orf75 | 64149 | 203830_at | 0.3101 | 0.0000 | |
| GSE26886 | C17orf75 | 64149 | 203830_at | 1.0713 | 0.0000 | |
| GSE29001 | C17orf75 | 64149 | 203830_at | 0.8639 | 0.0263 | |
| GSE38129 | C17orf75 | 64149 | 203830_at | 1.0048 | 0.0000 | |
| GSE45670 | C17orf75 | 64149 | 203830_at | 0.5209 | 0.0087 | |
| GSE53622 | C17orf75 | 64149 | 133571 | 0.6647 | 0.0000 | |
| GSE53624 | C17orf75 | 64149 | 133571 | 0.7910 | 0.0000 | |
| GSE63941 | C17orf75 | 64149 | 203830_at | 0.4002 | 0.4909 | |
| GSE77861 | C17orf75 | 64149 | 203830_at | 0.5010 | 0.0381 | |
| GSE97050 | C17orf75 | 64149 | A_23_P15639 | 0.3007 | 0.2850 | |
| SRP007169 | C17orf75 | 64149 | RNAseq | 1.0218 | 0.0075 | |
| SRP008496 | C17orf75 | 64149 | RNAseq | 0.8040 | 0.0040 | |
| SRP064894 | C17orf75 | 64149 | RNAseq | 0.5573 | 0.0010 | |
| SRP133303 | C17orf75 | 64149 | RNAseq | 0.2922 | 0.0085 | |
| SRP159526 | C17orf75 | 64149 | RNAseq | 0.6604 | 0.0033 | |
| SRP193095 | C17orf75 | 64149 | RNAseq | 0.2387 | 0.0026 | |
| SRP219564 | C17orf75 | 64149 | RNAseq | 0.5776 | 0.0282 | |
| TCGA | C17orf75 | 64149 | RNAseq | 0.1487 | 0.0228 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by C17orf75 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C17orf75:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C17orf75 | 64149 | 9 | 2 | 19 | |
| GSE20123 | C17orf75 | 64149 | 8 | 2 | 20 | |
| GSE43470 | C17orf75 | 64149 | 1 | 1 | 41 | |
| GSE46452 | C17orf75 | 64149 | 33 | 1 | 25 | |
| GSE47630 | C17orf75 | 64149 | 7 | 1 | 32 | |
| GSE54993 | C17orf75 | 64149 | 3 | 3 | 64 | |
| GSE54994 | C17orf75 | 64149 | 7 | 6 | 40 | |
| GSE60625 | C17orf75 | 64149 | 4 | 0 | 7 | |
| GSE74703 | C17orf75 | 64149 | 1 | 1 | 34 | |
| GSE74704 | C17orf75 | 64149 | 6 | 2 | 12 | |
| TCGA | C17orf75 | 64149 | 19 | 9 | 68 |
Total number of gains: 98; Total number of losses: 28; Total Number of normals: 362.
Somatic mutations of C17orf75:
Generating mutation plots.
Highly correlated genes for C17orf75:
Showing top 20/1712 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C17orf75 | ZFHX3 | 0.812848 | 3 | 0 | 3 |
| C17orf75 | RNF217 | 0.800963 | 3 | 0 | 3 |
| C17orf75 | HELB | 0.783022 | 3 | 0 | 3 |
| C17orf75 | TMEM65 | 0.761438 | 3 | 0 | 3 |
| C17orf75 | SAP130 | 0.761317 | 3 | 0 | 3 |
| C17orf75 | SLC35B2 | 0.753214 | 3 | 0 | 3 |
| C17orf75 | NF1 | 0.751954 | 3 | 0 | 3 |
| C17orf75 | ANKRD11 | 0.74797 | 3 | 0 | 3 |
| C17orf75 | USP3 | 0.745473 | 3 | 0 | 3 |
| C17orf75 | BIRC3 | 0.742624 | 3 | 0 | 3 |
| C17orf75 | MMS22L | 0.742212 | 3 | 0 | 3 |
| C17orf75 | TTBK2 | 0.73855 | 3 | 0 | 3 |
| C17orf75 | PTCD1 | 0.731374 | 3 | 0 | 3 |
| C17orf75 | CMC1 | 0.730418 | 3 | 0 | 3 |
| C17orf75 | PET117 | 0.727322 | 4 | 0 | 4 |
| C17orf75 | RAB34 | 0.721678 | 3 | 0 | 3 |
| C17orf75 | CWF19L1 | 0.720449 | 3 | 0 | 3 |
| C17orf75 | DHX40 | 0.720282 | 4 | 0 | 4 |
| C17orf75 | RAB11FIP5 | 0.717251 | 3 | 0 | 3 |
| C17orf75 | RAPGEF6 | 0.715609 | 3 | 0 | 3 |
For details and further investigation, click here
