| Full name: TNF receptor associated factor 7 | Alias Symbol: RNF119|DKFZp586I021|MGC7807 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 84231 | HGNC ID: HGNC:20456 | Ensembl Gene: ENSG00000131653 | OMIM ID: 606692 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TRAF7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAF7 | 84231 | 223031_s_at | 0.5498 | 0.3355 | |
| GSE26886 | TRAF7 | 84231 | 223031_s_at | 0.4188 | 0.0060 | |
| GSE45670 | TRAF7 | 84231 | 223031_s_at | 0.5000 | 0.0001 | |
| GSE63941 | TRAF7 | 84231 | 223031_s_at | 0.3368 | 0.2191 | |
| GSE77861 | TRAF7 | 84231 | 223031_s_at | 0.5781 | 0.0342 | |
| GSE97050 | TRAF7 | 84231 | A_24_P53150 | 0.2521 | 0.3552 | |
| SRP007169 | TRAF7 | 84231 | RNAseq | 0.1037 | 0.7869 | |
| SRP008496 | TRAF7 | 84231 | RNAseq | 0.0116 | 0.9596 | |
| SRP064894 | TRAF7 | 84231 | RNAseq | 0.2456 | 0.1970 | |
| SRP133303 | TRAF7 | 84231 | RNAseq | 0.5227 | 0.0139 | |
| SRP159526 | TRAF7 | 84231 | RNAseq | 0.4378 | 0.2836 | |
| SRP193095 | TRAF7 | 84231 | RNAseq | 0.3815 | 0.0011 | |
| SRP219564 | TRAF7 | 84231 | RNAseq | 0.1669 | 0.4744 | |
| TCGA | TRAF7 | 84231 | RNAseq | 0.1362 | 0.0036 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRAF7 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TRAF7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAF7 | 84231 | 5 | 5 | 20 | |
| GSE20123 | TRAF7 | 84231 | 5 | 4 | 21 | |
| GSE43470 | TRAF7 | 84231 | 4 | 7 | 32 | |
| GSE46452 | TRAF7 | 84231 | 38 | 1 | 20 | |
| GSE47630 | TRAF7 | 84231 | 13 | 6 | 21 | |
| GSE54993 | TRAF7 | 84231 | 3 | 5 | 62 | |
| GSE54994 | TRAF7 | 84231 | 5 | 9 | 39 | |
| GSE60625 | TRAF7 | 84231 | 4 | 0 | 7 | |
| GSE74703 | TRAF7 | 84231 | 4 | 5 | 27 | |
| GSE74704 | TRAF7 | 84231 | 3 | 2 | 15 | |
| TCGA | TRAF7 | 84231 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of TRAF7:
Generating mutation plots.
Highly correlated genes for TRAF7:
Showing top 20/1199 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAF7 | PALB2 | 0.863574 | 4 | 0 | 4 |
| TRAF7 | SPNS1 | 0.845477 | 4 | 0 | 4 |
| TRAF7 | DTYMK | 0.845149 | 4 | 0 | 4 |
| TRAF7 | PSMG3 | 0.813567 | 5 | 0 | 5 |
| TRAF7 | MASTL | 0.801449 | 3 | 0 | 3 |
| TRAF7 | RBCK1 | 0.788879 | 4 | 0 | 4 |
| TRAF7 | CPSF3 | 0.786919 | 5 | 0 | 5 |
| TRAF7 | PSMD9 | 0.785819 | 3 | 0 | 3 |
| TRAF7 | MRPL11 | 0.777081 | 3 | 0 | 3 |
| TRAF7 | UBA6 | 0.769663 | 3 | 0 | 3 |
| TRAF7 | CLSPN | 0.767555 | 4 | 0 | 4 |
| TRAF7 | RAD18 | 0.767298 | 3 | 0 | 3 |
| TRAF7 | FARS2 | 0.766699 | 3 | 0 | 3 |
| TRAF7 | LRIF1 | 0.765952 | 3 | 0 | 3 |
| TRAF7 | SEMA3C | 0.763387 | 3 | 0 | 3 |
| TRAF7 | KDM1A | 0.762962 | 3 | 0 | 3 |
| TRAF7 | RPA3 | 0.762731 | 6 | 0 | 6 |
| TRAF7 | PDPR | 0.758903 | 4 | 0 | 4 |
| TRAF7 | ANKRD11 | 0.751064 | 3 | 0 | 3 |
| TRAF7 | ALKBH6 | 0.74738 | 4 | 0 | 4 |
For details and further investigation, click here
