| Full name: RNA binding motif protein 4 | Alias Symbol: LARK|RBM4A|ZCRB3A|ZCCHC21 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 5936 | HGNC ID: HGNC:9901 | Ensembl Gene: ENSG00000173933 | OMIM ID: 602571 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RBM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM4 | 5936 | 227979_at | -0.2815 | 0.5152 | |
| GSE26886 | RBM4 | 5936 | 227979_at | 1.1532 | 0.0001 | |
| GSE45670 | RBM4 | 5936 | 227979_at | -0.5950 | 0.0154 | |
| GSE63941 | RBM4 | 5936 | 227979_at | 0.2836 | 0.7600 | |
| GSE77861 | RBM4 | 5936 | 227979_at | 0.0506 | 0.8904 | |
| GSE97050 | RBM4 | 5936 | A_23_P13033 | 0.1599 | 0.4856 | |
| SRP007169 | RBM4 | 5936 | RNAseq | -0.7846 | 0.0445 | |
| SRP008496 | RBM4 | 5936 | RNAseq | -0.4663 | 0.0383 | |
| SRP064894 | RBM4 | 5936 | RNAseq | -0.0370 | 0.8448 | |
| SRP133303 | RBM4 | 5936 | RNAseq | 0.2831 | 0.0830 | |
| SRP159526 | RBM4 | 5936 | RNAseq | 0.4999 | 0.1007 | |
| SRP193095 | RBM4 | 5936 | RNAseq | -0.0736 | 0.3852 | |
| SRP219564 | RBM4 | 5936 | RNAseq | -0.1089 | 0.6785 | |
| TCGA | RBM4 | 5936 | RNAseq | 0.0501 | 0.2748 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RBM4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RBM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM4 | 5936 | 9 | 4 | 17 | |
| GSE20123 | RBM4 | 5936 | 9 | 4 | 17 | |
| GSE43470 | RBM4 | 5936 | 6 | 1 | 36 | |
| GSE46452 | RBM4 | 5936 | 12 | 3 | 44 | |
| GSE47630 | RBM4 | 5936 | 9 | 4 | 27 | |
| GSE54993 | RBM4 | 5936 | 3 | 0 | 67 | |
| GSE54994 | RBM4 | 5936 | 10 | 4 | 39 | |
| GSE60625 | RBM4 | 5936 | 0 | 3 | 8 | |
| GSE74703 | RBM4 | 5936 | 4 | 0 | 32 | |
| GSE74704 | RBM4 | 5936 | 7 | 2 | 11 | |
| TCGA | RBM4 | 5936 | 27 | 7 | 62 |
Total number of gains: 96; Total number of losses: 32; Total Number of normals: 360.
Somatic mutations of RBM4:
Generating mutation plots.
Highly correlated genes for RBM4:
Showing top 20/133 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM4 | SCAF8 | 0.785463 | 3 | 0 | 3 |
| RBM4 | MRPL20 | 0.780899 | 3 | 0 | 3 |
| RBM4 | RBBP6 | 0.762235 | 3 | 0 | 3 |
| RBM4 | PIP4K2B | 0.755853 | 3 | 0 | 3 |
| RBM4 | METTL5 | 0.755584 | 3 | 0 | 3 |
| RBM4 | POLR2I | 0.751229 | 3 | 0 | 3 |
| RBM4 | ZNF195 | 0.74884 | 3 | 0 | 3 |
| RBM4 | ANKRD11 | 0.747791 | 3 | 0 | 3 |
| RBM4 | TMEM131 | 0.747548 | 3 | 0 | 3 |
| RBM4 | SRGAP1 | 0.746958 | 3 | 0 | 3 |
| RBM4 | BAD | 0.745801 | 3 | 0 | 3 |
| RBM4 | OTUD7B | 0.745402 | 3 | 0 | 3 |
| RBM4 | GPATCH1 | 0.744302 | 3 | 0 | 3 |
| RBM4 | KDM4B | 0.74126 | 3 | 0 | 3 |
| RBM4 | CEP350 | 0.736882 | 3 | 0 | 3 |
| RBM4 | RBM26 | 0.732998 | 3 | 0 | 3 |
| RBM4 | LRRC47 | 0.73218 | 3 | 0 | 3 |
| RBM4 | EIF2D | 0.727746 | 3 | 0 | 3 |
| RBM4 | UBE2E3 | 0.722127 | 3 | 0 | 3 |
| RBM4 | REPS1 | 0.721113 | 3 | 0 | 3 |
For details and further investigation, click here
