| Full name: MIER family member 3 | Alias Symbol: FLJ35954|DKFZp686L09111|DKFZp781I1119 | ||
| Type: protein-coding gene | Cytoband: 5q11.2 | ||
| Entrez ID: 166968 | HGNC ID: HGNC:26678 | Ensembl Gene: ENSG00000155545 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MIER3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MIER3 | 166968 | 228961_at | -0.1255 | 0.6931 | |
| GSE26886 | MIER3 | 166968 | 228961_at | -0.2686 | 0.3535 | |
| GSE45670 | MIER3 | 166968 | 228961_at | -0.1681 | 0.2363 | |
| GSE53622 | MIER3 | 166968 | 109179 | -0.0066 | 0.9292 | |
| GSE53624 | MIER3 | 166968 | 109179 | -0.0757 | 0.2351 | |
| GSE63941 | MIER3 | 166968 | 228961_at | -0.4391 | 0.3494 | |
| GSE77861 | MIER3 | 166968 | 231975_s_at | -0.1852 | 0.2704 | |
| GSE97050 | MIER3 | 166968 | A_23_P18993 | -0.0254 | 0.9348 | |
| SRP007169 | MIER3 | 166968 | RNAseq | -0.6415 | 0.0967 | |
| SRP008496 | MIER3 | 166968 | RNAseq | -0.5473 | 0.0555 | |
| SRP064894 | MIER3 | 166968 | RNAseq | -0.5774 | 0.0180 | |
| SRP133303 | MIER3 | 166968 | RNAseq | 0.1543 | 0.2501 | |
| SRP159526 | MIER3 | 166968 | RNAseq | -0.2032 | 0.2870 | |
| SRP193095 | MIER3 | 166968 | RNAseq | -0.7110 | 0.0000 | |
| SRP219564 | MIER3 | 166968 | RNAseq | -0.5423 | 0.0344 | |
| TCGA | MIER3 | 166968 | RNAseq | -0.1407 | 0.0103 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MIER3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MIER3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MIER3 | 166968 | 0 | 13 | 17 | |
| GSE20123 | MIER3 | 166968 | 0 | 13 | 17 | |
| GSE43470 | MIER3 | 166968 | 1 | 12 | 30 | |
| GSE46452 | MIER3 | 166968 | 0 | 28 | 31 | |
| GSE47630 | MIER3 | 166968 | 2 | 16 | 22 | |
| GSE54993 | MIER3 | 166968 | 8 | 1 | 61 | |
| GSE54994 | MIER3 | 166968 | 2 | 19 | 32 | |
| GSE60625 | MIER3 | 166968 | 0 | 0 | 11 | |
| GSE74703 | MIER3 | 166968 | 1 | 9 | 26 | |
| GSE74704 | MIER3 | 166968 | 0 | 6 | 14 | |
| TCGA | MIER3 | 166968 | 7 | 47 | 42 |
Total number of gains: 21; Total number of losses: 164; Total Number of normals: 303.
Somatic mutations of MIER3:
Generating mutation plots.
Highly correlated genes for MIER3:
Showing top 20/246 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MIER3 | HSPA2 | 0.784435 | 3 | 0 | 3 |
| MIER3 | NR2C2 | 0.782941 | 3 | 0 | 3 |
| MIER3 | CUL4B | 0.776689 | 3 | 0 | 3 |
| MIER3 | ANKRD28 | 0.775363 | 3 | 0 | 3 |
| MIER3 | PSMD5 | 0.77422 | 3 | 0 | 3 |
| MIER3 | CLK1 | 0.759869 | 3 | 0 | 3 |
| MIER3 | BTBD7 | 0.758315 | 3 | 0 | 3 |
| MIER3 | DENND4C | 0.756091 | 3 | 0 | 3 |
| MIER3 | ACBD5 | 0.752053 | 3 | 0 | 3 |
| MIER3 | FBXO8 | 0.743389 | 3 | 0 | 3 |
| MIER3 | PITPNM3 | 0.741825 | 3 | 0 | 3 |
| MIER3 | NCOA4 | 0.738903 | 3 | 0 | 3 |
| MIER3 | AKAP9 | 0.733961 | 3 | 0 | 3 |
| MIER3 | MLLT10 | 0.731131 | 4 | 0 | 4 |
| MIER3 | CTBS | 0.725828 | 3 | 0 | 3 |
| MIER3 | AGL | 0.720238 | 4 | 0 | 4 |
| MIER3 | RLIM | 0.719504 | 3 | 0 | 3 |
| MIER3 | NTAN1 | 0.717659 | 3 | 0 | 3 |
| MIER3 | LEPROT | 0.714251 | 3 | 0 | 3 |
| MIER3 | CWF19L2 | 0.707855 | 3 | 0 | 3 |
For details and further investigation, click here
