| Full name: anoctamin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 57101 | HGNC ID: HGNC:1183 | Ensembl Gene: ENSG00000047617 | OMIM ID: 610109 |
| Drug and gene relationship at DGIdb | |||
ANO2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of ANO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANO2 | 57101 | 220111_s_at | 0.0066 | 0.9831 | |
| GSE20347 | ANO2 | 57101 | 220111_s_at | 0.1115 | 0.0563 | |
| GSE23400 | ANO2 | 57101 | 220111_s_at | -0.0606 | 0.0894 | |
| GSE26886 | ANO2 | 57101 | 234718_at | -0.4496 | 0.0024 | |
| GSE29001 | ANO2 | 57101 | 220111_s_at | -0.0800 | 0.6178 | |
| GSE38129 | ANO2 | 57101 | 220111_s_at | -0.0313 | 0.6286 | |
| GSE45670 | ANO2 | 57101 | 234718_at | 0.0298 | 0.8436 | |
| GSE53622 | ANO2 | 57101 | 148623 | -0.3805 | 0.0000 | |
| GSE53624 | ANO2 | 57101 | 148623 | -0.2814 | 0.0032 | |
| GSE63941 | ANO2 | 57101 | 234718_at | 0.1733 | 0.2651 | |
| GSE77861 | ANO2 | 57101 | 234718_at | -0.1877 | 0.0609 | |
| GSE97050 | ANO2 | 57101 | A_32_P141238 | -0.0494 | 0.8704 | |
| SRP133303 | ANO2 | 57101 | RNAseq | -0.6005 | 0.0238 | |
| SRP159526 | ANO2 | 57101 | RNAseq | -0.7386 | 0.0657 | |
| SRP193095 | ANO2 | 57101 | RNAseq | 0.5832 | 0.0050 | |
| SRP219564 | ANO2 | 57101 | RNAseq | -0.2866 | 0.5359 | |
| TCGA | ANO2 | 57101 | RNAseq | -0.8776 | 0.0034 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANO2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANO2 | 57101 | 7 | 4 | 19 | |
| GSE20123 | ANO2 | 57101 | 7 | 4 | 19 | |
| GSE43470 | ANO2 | 57101 | 9 | 3 | 31 | |
| GSE46452 | ANO2 | 57101 | 10 | 1 | 48 | |
| GSE47630 | ANO2 | 57101 | 12 | 2 | 26 | |
| GSE54993 | ANO2 | 57101 | 1 | 10 | 59 | |
| GSE54994 | ANO2 | 57101 | 10 | 2 | 41 | |
| GSE60625 | ANO2 | 57101 | 0 | 1 | 10 | |
| GSE74703 | ANO2 | 57101 | 8 | 2 | 26 | |
| GSE74704 | ANO2 | 57101 | 4 | 2 | 14 | |
| TCGA | ANO2 | 57101 | 40 | 6 | 50 |
Total number of gains: 108; Total number of losses: 37; Total Number of normals: 343.
Somatic mutations of ANO2:
Generating mutation plots.
Highly correlated genes for ANO2:
Showing top 20/441 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANO2 | PCSK4 | 0.701379 | 3 | 0 | 3 |
| ANO2 | OLIG3 | 0.696235 | 3 | 0 | 3 |
| ANO2 | GPLD1 | 0.663108 | 7 | 0 | 6 |
| ANO2 | C6orf15 | 0.652632 | 4 | 0 | 4 |
| ANO2 | LINC01226 | 0.649139 | 4 | 0 | 3 |
| ANO2 | OR10C1 | 0.64864 | 5 | 0 | 5 |
| ANO2 | HOXC4 | 0.64449 | 3 | 0 | 3 |
| ANO2 | SV2C | 0.641362 | 4 | 0 | 4 |
| ANO2 | DDX4 | 0.639242 | 3 | 0 | 3 |
| ANO2 | F5 | 0.634546 | 3 | 0 | 3 |
| ANO2 | MC3R | 0.630142 | 5 | 0 | 3 |
| ANO2 | MTUS2-AS1 | 0.6295 | 3 | 0 | 3 |
| ANO2 | TBXA2R | 0.628779 | 4 | 0 | 4 |
| ANO2 | TAS2R39 | 0.627836 | 3 | 0 | 3 |
| ANO2 | SPNS3 | 0.626352 | 3 | 0 | 3 |
| ANO2 | HHIP | 0.624951 | 5 | 0 | 3 |
| ANO2 | AQP6 | 0.624497 | 6 | 0 | 6 |
| ANO2 | PPP1R14D | 0.622321 | 5 | 0 | 4 |
| ANO2 | OR1J2 | 0.621576 | 4 | 0 | 3 |
| ANO2 | KCNG1 | 0.618103 | 4 | 0 | 4 |
For details and further investigation, click here
