| Full name: protein phosphatase 1 regulatory inhibitor subunit 14D | Alias Symbol: CPI17-like|FLJ20251|GBPI-1|MGC119014|MGC119016 | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 54866 | HGNC ID: HGNC:14953 | Ensembl Gene: ENSG00000166143 | OMIM ID: 613256 |
| Drug and gene relationship at DGIdb | |||
Expression of PPP1R14D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R14D | 54866 | 220082_at | -0.0760 | 0.7678 | |
| GSE20347 | PPP1R14D | 54866 | 220082_at | 0.0646 | 0.4841 | |
| GSE23400 | PPP1R14D | 54866 | 220082_at | -0.1531 | 0.0001 | |
| GSE26886 | PPP1R14D | 54866 | 220082_at | 0.3759 | 0.0473 | |
| GSE29001 | PPP1R14D | 54866 | 220082_at | 0.0379 | 0.8672 | |
| GSE38129 | PPP1R14D | 54866 | 220082_at | -0.0098 | 0.9117 | |
| GSE45670 | PPP1R14D | 54866 | 220082_at | 0.1367 | 0.1621 | |
| GSE53622 | PPP1R14D | 54866 | 14659 | 0.2883 | 0.0004 | |
| GSE53624 | PPP1R14D | 54866 | 14659 | 0.1910 | 0.0100 | |
| GSE63941 | PPP1R14D | 54866 | 220082_at | 0.0521 | 0.8451 | |
| GSE77861 | PPP1R14D | 54866 | 220082_at | 0.0131 | 0.9351 | |
| GSE97050 | PPP1R14D | 54866 | A_23_P129312 | 0.0733 | 0.7561 | |
| TCGA | PPP1R14D | 54866 | RNAseq | -1.3534 | 0.0857 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPP1R14D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP1R14D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R14D | 54866 | 3 | 6 | 21 | |
| GSE20123 | PPP1R14D | 54866 | 3 | 6 | 21 | |
| GSE43470 | PPP1R14D | 54866 | 4 | 6 | 33 | |
| GSE46452 | PPP1R14D | 54866 | 3 | 7 | 49 | |
| GSE47630 | PPP1R14D | 54866 | 8 | 11 | 21 | |
| GSE54993 | PPP1R14D | 54866 | 4 | 6 | 60 | |
| GSE54994 | PPP1R14D | 54866 | 5 | 7 | 41 | |
| GSE60625 | PPP1R14D | 54866 | 4 | 0 | 7 | |
| GSE74703 | PPP1R14D | 54866 | 4 | 5 | 27 | |
| GSE74704 | PPP1R14D | 54866 | 2 | 4 | 14 | |
| TCGA | PPP1R14D | 54866 | 11 | 18 | 67 |
Total number of gains: 51; Total number of losses: 76; Total Number of normals: 361.
Somatic mutations of PPP1R14D:
Generating mutation plots.
Highly correlated genes for PPP1R14D:
Showing top 20/621 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R14D | HOXB6 | 0.778987 | 3 | 0 | 3 |
| PPP1R14D | IFNA4 | 0.751263 | 5 | 0 | 5 |
| PPP1R14D | BCL2L10 | 0.736724 | 4 | 0 | 3 |
| PPP1R14D | HRC | 0.730539 | 5 | 0 | 5 |
| PPP1R14D | HHATL | 0.718124 | 3 | 0 | 3 |
| PPP1R14D | MOGAT3 | 0.717888 | 3 | 0 | 3 |
| PPP1R14D | HCRT | 0.715866 | 5 | 0 | 5 |
| PPP1R14D | TMPRSS5 | 0.708633 | 5 | 0 | 4 |
| PPP1R14D | PRDM13 | 0.707402 | 4 | 0 | 3 |
| PPP1R14D | CYP2D6 | 0.704689 | 6 | 0 | 5 |
| PPP1R14D | EME2 | 0.703026 | 3 | 0 | 3 |
| PPP1R14D | OLIG3 | 0.693898 | 4 | 0 | 4 |
| PPP1R14D | GAD2 | 0.692669 | 4 | 0 | 4 |
| PPP1R14D | RNF17 | 0.691672 | 5 | 0 | 4 |
| PPP1R14D | B3GALT1 | 0.689437 | 5 | 0 | 5 |
| PPP1R14D | GP2 | 0.687642 | 4 | 0 | 4 |
| PPP1R14D | CHAT | 0.686966 | 4 | 0 | 3 |
| PPP1R14D | KRT76 | 0.685149 | 4 | 0 | 4 |
| PPP1R14D | IFNA10 | 0.679298 | 4 | 0 | 4 |
| PPP1R14D | C1QL2 | 0.678345 | 3 | 0 | 3 |
For details and further investigation, click here
