| Full name: OTU deubiquitinase 5 | Alias Symbol: DKFZp761A052|DUBA | ||
| Type: protein-coding gene | Cytoband: Xp11.23 | ||
| Entrez ID: 55593 | HGNC ID: HGNC:25402 | Ensembl Gene: ENSG00000068308 | OMIM ID: 300713 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
OTUD5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04622 | RIG-I-like receptor signaling pathway |
Expression of OTUD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OTUD5 | 55593 | 224745_x_at | -0.0215 | 0.9518 | |
| GSE26886 | OTUD5 | 55593 | 224745_x_at | 0.1073 | 0.4114 | |
| GSE45670 | OTUD5 | 55593 | 224745_x_at | 0.0810 | 0.5008 | |
| GSE53622 | OTUD5 | 55593 | 19121 | -0.1863 | 0.0004 | |
| GSE53624 | OTUD5 | 55593 | 19121 | -0.0028 | 0.9535 | |
| GSE63941 | OTUD5 | 55593 | 224745_x_at | 0.6017 | 0.0028 | |
| GSE77861 | OTUD5 | 55593 | 224745_x_at | -0.0033 | 0.9741 | |
| GSE97050 | OTUD5 | 55593 | A_23_P337550 | -0.1519 | 0.4742 | |
| SRP007169 | OTUD5 | 55593 | RNAseq | -1.0621 | 0.0026 | |
| SRP008496 | OTUD5 | 55593 | RNAseq | -0.9469 | 0.0000 | |
| SRP064894 | OTUD5 | 55593 | RNAseq | -0.0437 | 0.7683 | |
| SRP133303 | OTUD5 | 55593 | RNAseq | 0.0495 | 0.8165 | |
| SRP159526 | OTUD5 | 55593 | RNAseq | 0.1517 | 0.5379 | |
| SRP193095 | OTUD5 | 55593 | RNAseq | 0.0064 | 0.9570 | |
| SRP219564 | OTUD5 | 55593 | RNAseq | 0.0034 | 0.9885 | |
| TCGA | OTUD5 | 55593 | RNAseq | -0.0038 | 0.9352 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by OTUD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OTUD5:
No record found for this gene.
Somatic mutations of OTUD5:
Generating mutation plots.
Highly correlated genes for OTUD5:
Showing top 20/117 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OTUD5 | ZBTB48 | 0.846848 | 3 | 0 | 3 |
| OTUD5 | USHBP1 | 0.842292 | 3 | 0 | 3 |
| OTUD5 | BRSK1 | 0.777799 | 3 | 0 | 3 |
| OTUD5 | SPTBN4 | 0.730107 | 3 | 0 | 3 |
| OTUD5 | MRPS2 | 0.724732 | 3 | 0 | 3 |
| OTUD5 | ATP2B2 | 0.723631 | 3 | 0 | 3 |
| OTUD5 | ANO7 | 0.721547 | 3 | 0 | 3 |
| OTUD5 | CLDN14 | 0.717085 | 3 | 0 | 3 |
| OTUD5 | CPNE7 | 0.708539 | 3 | 0 | 3 |
| OTUD5 | ZNF630 | 0.705954 | 3 | 0 | 3 |
| OTUD5 | SHARPIN | 0.705842 | 3 | 0 | 3 |
| OTUD5 | CABP1 | 0.704019 | 3 | 0 | 3 |
| OTUD5 | LMAN1L | 0.701254 | 3 | 0 | 3 |
| OTUD5 | ZNF705G | 0.699318 | 3 | 0 | 3 |
| OTUD5 | PRODH2 | 0.695324 | 4 | 0 | 3 |
| OTUD5 | GRIPAP1 | 0.692567 | 5 | 0 | 4 |
| OTUD5 | TMEM52 | 0.690466 | 4 | 0 | 4 |
| OTUD5 | FERD3L | 0.689277 | 4 | 0 | 3 |
| OTUD5 | MPP2 | 0.689125 | 4 | 0 | 3 |
| OTUD5 | LRRC3 | 0.680931 | 3 | 0 | 3 |
For details and further investigation, click here
