| Full name: nucleoredoxin like 1 | Alias Symbol: RDCVF | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 115861 | HGNC ID: HGNC:25179 | Ensembl Gene: ENSG00000171773 | OMIM ID: 608791 |
| Drug and gene relationship at DGIdb | |||
Expression of NXNL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NXNL1 | 115861 | 1553755_at | 0.0127 | 0.9735 | |
| GSE26886 | NXNL1 | 115861 | 1553755_at | 0.1579 | 0.2107 | |
| GSE45670 | NXNL1 | 115861 | 1553755_at | 0.2384 | 0.0133 | |
| GSE63941 | NXNL1 | 115861 | 1553755_at | 0.2789 | 0.0738 | |
| GSE77861 | NXNL1 | 115861 | 1553755_at | 0.0388 | 0.7529 | |
| GSE97050 | NXNL1 | 115861 | A_23_P384650 | 0.0855 | 0.7237 | |
| SRP133303 | NXNL1 | 115861 | RNAseq | 0.3549 | 0.1825 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NXNL1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NXNL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NXNL1 | 115861 | 4 | 4 | 22 | |
| GSE20123 | NXNL1 | 115861 | 3 | 2 | 25 | |
| GSE43470 | NXNL1 | 115861 | 2 | 6 | 35 | |
| GSE46452 | NXNL1 | 115861 | 47 | 1 | 11 | |
| GSE47630 | NXNL1 | 115861 | 4 | 8 | 28 | |
| GSE54993 | NXNL1 | 115861 | 15 | 4 | 51 | |
| GSE54994 | NXNL1 | 115861 | 6 | 14 | 33 | |
| GSE60625 | NXNL1 | 115861 | 9 | 0 | 2 | |
| GSE74703 | NXNL1 | 115861 | 2 | 4 | 30 | |
| GSE74704 | NXNL1 | 115861 | 0 | 2 | 18 | |
| TCGA | NXNL1 | 115861 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of NXNL1:
Generating mutation plots.
Highly correlated genes for NXNL1:
Showing top 20/250 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NXNL1 | HTR6 | 0.841258 | 3 | 0 | 3 |
| NXNL1 | AGAP2 | 0.801898 | 3 | 0 | 3 |
| NXNL1 | SCGN | 0.793878 | 3 | 0 | 3 |
| NXNL1 | RPH3A | 0.788197 | 3 | 0 | 3 |
| NXNL1 | TTBK1 | 0.766024 | 3 | 0 | 3 |
| NXNL1 | HCRT | 0.764755 | 3 | 0 | 3 |
| NXNL1 | CDH4 | 0.761955 | 3 | 0 | 3 |
| NXNL1 | PROCA1 | 0.761877 | 3 | 0 | 3 |
| NXNL1 | SMOC1 | 0.747449 | 3 | 0 | 3 |
| NXNL1 | EGR4 | 0.746427 | 3 | 0 | 3 |
| NXNL1 | ANO7 | 0.744242 | 3 | 0 | 3 |
| NXNL1 | CIB3 | 0.742225 | 3 | 0 | 3 |
| NXNL1 | CARNS1 | 0.727785 | 3 | 0 | 3 |
| NXNL1 | SHISA7 | 0.72206 | 4 | 0 | 4 |
| NXNL1 | CABP4 | 0.721772 | 4 | 0 | 3 |
| NXNL1 | ROS1 | 0.718956 | 3 | 0 | 3 |
| NXNL1 | TSSK3 | 0.717983 | 3 | 0 | 3 |
| NXNL1 | CALCA | 0.713406 | 5 | 0 | 4 |
| NXNL1 | NXPH3 | 0.713262 | 3 | 0 | 3 |
| NXNL1 | C22orf23 | 0.71136 | 4 | 0 | 4 |
For details and further investigation, click here
