| Full name: apolipoprotein B mRNA editing enzyme catalytic subunit 3G | Alias Symbol: CEM15|MDS019|dJ494G10.1|FLJ12740|bK150C2.7 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 60489 | HGNC ID: HGNC:17357 | Ensembl Gene: ENSG00000239713 | OMIM ID: 607113 |
| Drug and gene relationship at DGIdb | |||
Expression of APOBEC3G:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APOBEC3G | 60489 | 204205_at | 0.1865 | 0.8648 | |
| GSE20347 | APOBEC3G | 60489 | 204205_at | 0.4897 | 0.1275 | |
| GSE23400 | APOBEC3G | 60489 | 215579_at | -0.1210 | 0.0056 | |
| GSE26886 | APOBEC3G | 60489 | 204205_at | 1.9467 | 0.0007 | |
| GSE29001 | APOBEC3G | 60489 | 204205_at | 0.9323 | 0.0915 | |
| GSE38129 | APOBEC3G | 60489 | 204205_at | 0.5692 | 0.0616 | |
| GSE45670 | APOBEC3G | 60489 | 204205_at | 0.2460 | 0.6284 | |
| GSE53622 | APOBEC3G | 60489 | 22104 | 0.8233 | 0.0000 | |
| GSE53624 | APOBEC3G | 60489 | 22104 | 0.6836 | 0.0000 | |
| GSE63941 | APOBEC3G | 60489 | 215579_at | 0.4634 | 0.0020 | |
| GSE77861 | APOBEC3G | 60489 | 215579_at | -0.0808 | 0.5717 | |
| GSE97050 | APOBEC3G | 60489 | A_23_P143713 | 0.9602 | 0.1453 | |
| SRP007169 | APOBEC3G | 60489 | RNAseq | 1.7092 | 0.0754 | |
| SRP064894 | APOBEC3G | 60489 | RNAseq | 0.6882 | 0.0073 | |
| SRP133303 | APOBEC3G | 60489 | RNAseq | 0.5530 | 0.0655 | |
| SRP159526 | APOBEC3G | 60489 | RNAseq | 0.9269 | 0.2001 | |
| SRP193095 | APOBEC3G | 60489 | RNAseq | 0.4906 | 0.0065 | |
| SRP219564 | APOBEC3G | 60489 | RNAseq | 1.2768 | 0.0384 | |
| TCGA | APOBEC3G | 60489 | RNAseq | 0.5644 | 0.0010 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by APOBEC3G expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APOBEC3G:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APOBEC3G | 60489 | 6 | 5 | 19 | |
| GSE20123 | APOBEC3G | 60489 | 6 | 4 | 20 | |
| GSE43470 | APOBEC3G | 60489 | 5 | 5 | 33 | |
| GSE46452 | APOBEC3G | 60489 | 32 | 2 | 25 | |
| GSE47630 | APOBEC3G | 60489 | 9 | 4 | 27 | |
| GSE54993 | APOBEC3G | 60489 | 3 | 6 | 61 | |
| GSE54994 | APOBEC3G | 60489 | 9 | 7 | 37 | |
| GSE60625 | APOBEC3G | 60489 | 5 | 0 | 6 | |
| GSE74703 | APOBEC3G | 60489 | 5 | 4 | 27 | |
| GSE74704 | APOBEC3G | 60489 | 3 | 2 | 15 | |
| TCGA | APOBEC3G | 60489 | 27 | 15 | 54 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of APOBEC3G:
Generating mutation plots.
Highly correlated genes for APOBEC3G:
Showing top 20/451 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APOBEC3G | EXOC3L2 | 0.841937 | 3 | 0 | 3 |
| APOBEC3G | OCIAD2 | 0.780966 | 3 | 0 | 3 |
| APOBEC3G | RNF213 | 0.759452 | 3 | 0 | 3 |
| APOBEC3G | KRT18 | 0.746697 | 3 | 0 | 3 |
| APOBEC3G | GTPBP3 | 0.739187 | 3 | 0 | 3 |
| APOBEC3G | FGFR1OP | 0.724321 | 3 | 0 | 3 |
| APOBEC3G | WDR81 | 0.722535 | 3 | 0 | 3 |
| APOBEC3G | SNAI3 | 0.720417 | 3 | 0 | 3 |
| APOBEC3G | MORC2-AS1 | 0.712573 | 3 | 0 | 3 |
| APOBEC3G | GPR160 | 0.707915 | 3 | 0 | 3 |
| APOBEC3G | PARVG | 0.706061 | 5 | 0 | 4 |
| APOBEC3G | GJD3 | 0.697966 | 4 | 0 | 4 |
| APOBEC3G | GBP4 | 0.69692 | 6 | 0 | 6 |
| APOBEC3G | JAG2 | 0.688989 | 3 | 0 | 3 |
| APOBEC3G | HES4 | 0.685568 | 3 | 0 | 3 |
| APOBEC3G | GCNT1 | 0.684045 | 3 | 0 | 3 |
| APOBEC3G | BTN3A1 | 0.680814 | 8 | 0 | 8 |
| APOBEC3G | BIN2 | 0.678321 | 5 | 0 | 4 |
| APOBEC3G | ORAI1 | 0.677877 | 3 | 0 | 3 |
| APOBEC3G | CMTM7 | 0.675329 | 5 | 0 | 4 |
For details and further investigation, click here
