| Full name: gap junction protein delta 3 | Alias Symbol: CX31.9|GJA11|Cx30.2 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 125111 | HGNC ID: HGNC:19147 | Ensembl Gene: ENSG00000183153 | OMIM ID: 607425 |
| Drug and gene relationship at DGIdb | |||
Expression of GJD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GJD3 | 125111 | 230025_at | 0.1997 | 0.6127 | |
| GSE26886 | GJD3 | 125111 | 1553511_at | -0.0110 | 0.9392 | |
| GSE45670 | GJD3 | 125111 | 230025_at | 0.0131 | 0.9392 | |
| GSE63941 | GJD3 | 125111 | 1553511_at | 0.4410 | 0.0090 | |
| GSE77861 | GJD3 | 125111 | 1553511_at | -0.1666 | 0.3160 | |
| GSE97050 | GJD3 | 125111 | A_33_P3265301 | 0.5499 | 0.1313 | |
| SRP007169 | GJD3 | 125111 | RNAseq | 1.0585 | 0.1373 | |
| SRP064894 | GJD3 | 125111 | RNAseq | -0.1619 | 0.3800 | |
| SRP133303 | GJD3 | 125111 | RNAseq | -0.3245 | 0.0181 | |
| SRP159526 | GJD3 | 125111 | RNAseq | 0.2462 | 0.5130 | |
| SRP193095 | GJD3 | 125111 | RNAseq | 0.2785 | 0.0903 | |
| SRP219564 | GJD3 | 125111 | RNAseq | 0.0677 | 0.8159 | |
| TCGA | GJD3 | 125111 | RNAseq | 0.1845 | 0.0633 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GJD3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GJD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GJD3 | 125111 | 8 | 1 | 21 | |
| GSE20123 | GJD3 | 125111 | 8 | 1 | 21 | |
| GSE43470 | GJD3 | 125111 | 1 | 2 | 40 | |
| GSE46452 | GJD3 | 125111 | 34 | 0 | 25 | |
| GSE47630 | GJD3 | 125111 | 8 | 1 | 31 | |
| GSE54993 | GJD3 | 125111 | 3 | 4 | 63 | |
| GSE54994 | GJD3 | 125111 | 8 | 5 | 40 | |
| GSE60625 | GJD3 | 125111 | 4 | 0 | 7 | |
| GSE74703 | GJD3 | 125111 | 1 | 1 | 34 | |
| GSE74704 | GJD3 | 125111 | 5 | 1 | 14 | |
| TCGA | GJD3 | 125111 | 22 | 8 | 66 |
Total number of gains: 102; Total number of losses: 24; Total Number of normals: 362.
Somatic mutations of GJD3:
Generating mutation plots.
Highly correlated genes for GJD3:
Showing top 20/110 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GJD3 | PLXNC1 | 0.784651 | 3 | 0 | 3 |
| GJD3 | CCR1 | 0.714143 | 4 | 0 | 4 |
| GJD3 | LILRB3 | 0.713086 | 4 | 0 | 4 |
| GJD3 | GMFG | 0.710231 | 3 | 0 | 3 |
| GJD3 | SLAMF8 | 0.698019 | 4 | 0 | 3 |
| GJD3 | APOBEC3G | 0.697966 | 4 | 0 | 4 |
| GJD3 | AIF1 | 0.690095 | 5 | 0 | 4 |
| GJD3 | CD300A | 0.682508 | 5 | 0 | 4 |
| GJD3 | ITGAL | 0.678892 | 3 | 0 | 3 |
| GJD3 | WDR93 | 0.671703 | 4 | 0 | 3 |
| GJD3 | MEFV | 0.660023 | 4 | 0 | 3 |
| GJD3 | EXOC3L2 | 0.651575 | 4 | 0 | 3 |
| GJD3 | ITGB2 | 0.649766 | 4 | 0 | 3 |
| GJD3 | PRSS36 | 0.639551 | 3 | 0 | 3 |
| GJD3 | PLA2G7 | 0.637455 | 4 | 0 | 3 |
| GJD3 | RUNX2 | 0.635041 | 3 | 0 | 3 |
| GJD3 | ARHGAP25 | 0.634689 | 4 | 0 | 3 |
| GJD3 | ERGIC3 | 0.631266 | 3 | 0 | 3 |
| GJD3 | ZSCAN10 | 0.630105 | 3 | 0 | 3 |
| GJD3 | CD3D | 0.629038 | 3 | 0 | 3 |
For details and further investigation, click here
