PARVG

 

Full name: parvin gamma Alias Symbol: 
Type: protein-coding gene Cytoband: 22q13.31
Entrez ID: 64098 HGNC ID: HGNC:14654 Ensembl Gene: ENSG00000138964 OMIM ID: 608122
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

PARVG involved pathways:

KEGG pathway Description View
hsa04510Focal adhesion

 

Expression of PARVG:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PARVG 64098 223562_at 0.2590 0.7337
GSE26886 PARVG 64098 223562_at -0.1509 0.4610
GSE45670 PARVG 64098 223562_at 0.0973 0.5111
GSE53622 PARVG 64098 142783 0.1861 0.1384
GSE53624 PARVG 64098 142783 -0.0149 0.9270
GSE63941 PARVG 64098 223562_at 0.1134 0.5475
GSE77861 PARVG 64098 244229_at -0.0679 0.6571
GSE97050 PARVG 64098 A_23_P250413 0.8835 0.1672
SRP007169 PARVG 64098 RNAseq 1.0639 0.2554
SRP064894 PARVG 64098 RNAseq 0.7220 0.0200
SRP133303 PARVG 64098 RNAseq -0.4002 0.1178
SRP159526 PARVG 64098 RNAseq -0.6603 0.2417
SRP193095 PARVG 64098 RNAseq -0.2186 0.2748
SRP219564 PARVG 64098 RNAseq 0.5647 0.1754
TCGA PARVG 64098 RNAseq 0.2131 0.2122

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by PARVG expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PARVG:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PARVG 64098 5 7 18
GSE20123 PARVG 64098 4 6 20
GSE43470 PARVG 64098 3 6 34
GSE46452 PARVG 64098 31 2 26
GSE47630 PARVG 64098 9 4 27
GSE54993 PARVG 64098 3 6 61
GSE54994 PARVG 64098 11 8 34
GSE60625 PARVG 64098 5 0 6
GSE74703 PARVG 64098 3 4 29
GSE74704 PARVG 64098 2 3 15
TCGA PARVG 64098 26 15 55

Total number of gains: 102; Total number of losses: 61; Total Number of normals: 325.  


 

Somatic mutations of PARVG:

 

Generating mutation plots.

 

Highly correlated genes for PARVG:

 

Showing top 20/433 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PARVGARHGAP90.825911606
PARVGBIN20.801518605
PARVGANP32D0.792524303
PARVGKLRC30.774242303
PARVGPTPRC0.772854404
PARVGACAP10.772438505
PARVGKCNA30.764185404
PARVGCYTIP0.761273505
PARVGGPR1710.759847505
PARVGCORO1A0.759204706
PARVGTNFSF80.757753504
PARVGNCKAP1L0.754991706
PARVGEVI2B0.7499706
PARVGSPI10.748452605
PARVGZDHHC140.74843404
PARVGLCP20.746571606
PARVGDOCK20.746155606
PARVGCYTH40.741571605
PARVGPIK3CG0.740559505
PARVGCD370.740142706

For details and further investigation, click here