| Full name: glucosaminyl (N-acetyl) transferase 1 | Alias Symbol: C2GNT|NAGCT2 | ||
| Type: protein-coding gene | Cytoband: 9q21.13 | ||
| Entrez ID: 2650 | HGNC ID: HGNC:4203 | Ensembl Gene: ENSG00000187210 | OMIM ID: 600391 |
| Drug and gene relationship at DGIdb | |||
Expression of GCNT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GCNT1 | 2650 | 205505_at | 0.2385 | 0.4893 | |
| GSE20347 | GCNT1 | 2650 | 205505_at | 0.3708 | 0.0313 | |
| GSE23400 | GCNT1 | 2650 | 205505_at | 0.1021 | 0.0405 | |
| GSE26886 | GCNT1 | 2650 | 205505_at | 0.0021 | 0.9962 | |
| GSE29001 | GCNT1 | 2650 | 205505_at | 0.6479 | 0.0389 | |
| GSE38129 | GCNT1 | 2650 | 205505_at | 0.3906 | 0.0174 | |
| GSE45670 | GCNT1 | 2650 | 239761_at | -0.0346 | 0.9147 | |
| GSE53622 | GCNT1 | 2650 | 11058 | -0.1738 | 0.4191 | |
| GSE53624 | GCNT1 | 2650 | 11058 | 0.3419 | 0.0384 | |
| GSE63941 | GCNT1 | 2650 | 239761_at | 0.0159 | 0.9877 | |
| GSE77861 | GCNT1 | 2650 | 205505_at | 0.0216 | 0.8907 | |
| GSE97050 | GCNT1 | 2650 | A_33_P3282489 | 0.5158 | 0.2575 | |
| SRP007169 | GCNT1 | 2650 | RNAseq | 2.3273 | 0.0001 | |
| SRP008496 | GCNT1 | 2650 | RNAseq | 1.8194 | 0.0002 | |
| SRP064894 | GCNT1 | 2650 | RNAseq | 0.4682 | 0.0571 | |
| SRP133303 | GCNT1 | 2650 | RNAseq | 0.3274 | 0.2985 | |
| SRP159526 | GCNT1 | 2650 | RNAseq | 0.5950 | 0.3330 | |
| SRP193095 | GCNT1 | 2650 | RNAseq | -1.2480 | 0.0122 | |
| SRP219564 | GCNT1 | 2650 | RNAseq | 1.2982 | 0.0081 | |
| TCGA | GCNT1 | 2650 | RNAseq | -0.7923 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by GCNT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GCNT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GCNT1 | 2650 | 6 | 10 | 14 | |
| GSE20123 | GCNT1 | 2650 | 6 | 10 | 14 | |
| GSE43470 | GCNT1 | 2650 | 6 | 5 | 32 | |
| GSE46452 | GCNT1 | 2650 | 6 | 14 | 39 | |
| GSE47630 | GCNT1 | 2650 | 1 | 18 | 21 | |
| GSE54993 | GCNT1 | 2650 | 4 | 2 | 64 | |
| GSE54994 | GCNT1 | 2650 | 4 | 12 | 37 | |
| GSE60625 | GCNT1 | 2650 | 0 | 0 | 11 | |
| GSE74703 | GCNT1 | 2650 | 5 | 4 | 27 | |
| GSE74704 | GCNT1 | 2650 | 3 | 7 | 10 | |
| TCGA | GCNT1 | 2650 | 18 | 28 | 50 |
Total number of gains: 59; Total number of losses: 110; Total Number of normals: 319.
Somatic mutations of GCNT1:
Generating mutation plots.
Highly correlated genes for GCNT1:
Showing top 20/179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GCNT1 | LTB | 0.71265 | 3 | 0 | 3 |
| GCNT1 | ST8SIA4 | 0.708989 | 4 | 0 | 4 |
| GCNT1 | NAT10 | 0.702251 | 3 | 0 | 3 |
| GCNT1 | RNF4 | 0.700163 | 3 | 0 | 3 |
| GCNT1 | PIF1 | 0.69872 | 3 | 0 | 3 |
| GCNT1 | APOBEC3G | 0.684045 | 3 | 0 | 3 |
| GCNT1 | ATAD2 | 0.680553 | 3 | 0 | 3 |
| GCNT1 | RNASET2 | 0.680286 | 4 | 0 | 3 |
| GCNT1 | UCP2 | 0.675475 | 4 | 0 | 3 |
| GCNT1 | INTS7 | 0.674452 | 3 | 0 | 3 |
| GCNT1 | SDC4 | 0.673154 | 3 | 0 | 3 |
| GCNT1 | C5orf22 | 0.670065 | 3 | 0 | 3 |
| GCNT1 | ARL4C | 0.669192 | 3 | 0 | 3 |
| GCNT1 | KRI1 | 0.668092 | 3 | 0 | 3 |
| GCNT1 | ANPEP | 0.657312 | 3 | 0 | 3 |
| GCNT1 | TBK1 | 0.656272 | 3 | 0 | 3 |
| GCNT1 | RASGRP3 | 0.654555 | 4 | 0 | 4 |
| GCNT1 | TCN2 | 0.64866 | 4 | 0 | 3 |
| GCNT1 | CCNA2 | 0.644326 | 4 | 0 | 3 |
| GCNT1 | ARHGAP9 | 0.64421 | 5 | 0 | 4 |
For details and further investigation, click here
