RNF213

 

Full name: ring finger protein 213 Alias Symbol: KIAA1554|NET57|ALO17
Type: protein-coding gene Cytoband: 17q25.3
Entrez ID: 57674 HGNC ID: HGNC:14539 Ensembl Gene: ENSG00000173821 OMIM ID: 613768
Drug and gene relationship at DGIdb

 

Expression of RNF213:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RNF213 57674 225929_s_at 0.4824 0.4428
GSE26886 RNF213 57674 225929_s_at 0.0204 0.9448
GSE45670 RNF213 57674 225929_s_at 0.8604 0.0009
GSE63941 RNF213 57674 225929_s_at -0.4607 0.3237
GSE77861 RNF213 57674 225929_s_at 0.3961 0.1950
GSE97050 RNF213 A_19_P00804072 0.5048 0.2071
SRP007169 RNF213 57674 RNAseq 1.6577 0.0002
SRP008496 RNF213 57674 RNAseq 1.1510 0.0000
SRP064894 RNF213 57674 RNAseq 0.7739 0.0000
SRP133303 RNF213 57674 RNAseq 0.3872 0.0236
SRP159526 RNF213 57674 RNAseq -0.0326 0.9107
SRP193095 RNF213 57674 RNAseq 0.7707 0.0001
SRP219564 RNF213 57674 RNAseq 0.6893 0.1008
TCGA RNF213 57674 RNAseq 0.0522 0.3129

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by RNF213 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of RNF213:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RNF213 57674 4 3 23
GSE20123 RNF213 57674 4 3 23
GSE43470 RNF213 57674 3 5 35
GSE46452 RNF213 57674 34 0 25
GSE47630 RNF213 57674 9 1 30
GSE54993 RNF213 57674 2 5 63
GSE54994 RNF213 57674 10 6 37
GSE60625 RNF213 57674 6 0 5
GSE74703 RNF213 57674 3 3 30
GSE74704 RNF213 57674 4 3 13
TCGA RNF213 57674 28 10 58

Total number of gains: 107; Total number of losses: 39; Total Number of normals: 342.  


 

Somatic mutations of RNF213:

 

Generating mutation plots.

 

Highly correlated genes for RNF213:

 

Showing top 20/319 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RNF213PLSCR10.824157303
RNF213LY6E0.815675303
RNF213OAS20.79853404
RNF213BST20.792079303
RNF213HERC50.784014303
RNF213IRF70.776614303
RNF213ADAM170.764619303
RNF213APOBEC3G0.759452303
RNF213ATP13A10.75687303
RNF213USP180.754332403
RNF213PRDM150.747687303
RNF213TAP10.744901504
RNF213ADAR0.740073404
RNF213ZNF6180.733935303
RNF213LLPH0.732734303
RNF213DPP70.727827303
RNF213LIMK10.724551303
RNF213PARP140.724503504
RNF213PSMB80.723773504
RNF213PRR130.721573404

For details and further investigation, click here