| Full name: Fas activated serine/threonine kinase | Alias Symbol: FAST | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 10922 | HGNC ID: HGNC:24676 | Ensembl Gene: ENSG00000164896 | OMIM ID: 606965 |
| Drug and gene relationship at DGIdb | |||
Expression of FASTK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FASTK | 10922 | 214114_x_at | 0.0256 | 0.9628 | |
| GSE20347 | FASTK | 10922 | 214114_x_at | -0.0941 | 0.4162 | |
| GSE23400 | FASTK | 10922 | 214114_x_at | 0.0212 | 0.6929 | |
| GSE26886 | FASTK | 10922 | 214114_x_at | -0.2120 | 0.0949 | |
| GSE29001 | FASTK | 10922 | 214114_x_at | -0.0974 | 0.7639 | |
| GSE38129 | FASTK | 10922 | 214114_x_at | -0.0338 | 0.7325 | |
| GSE45670 | FASTK | 10922 | 214114_x_at | 0.1103 | 0.3809 | |
| GSE53622 | FASTK | 10922 | 10124 | -0.0932 | 0.0540 | |
| GSE53624 | FASTK | 10922 | 10124 | -0.0039 | 0.9460 | |
| GSE63941 | FASTK | 10922 | 214114_x_at | -0.3830 | 0.1447 | |
| GSE77861 | FASTK | 10922 | 214114_x_at | 0.1316 | 0.4707 | |
| GSE97050 | FASTK | 10922 | A_23_P502930 | 0.0143 | 0.9524 | |
| SRP007169 | FASTK | 10922 | RNAseq | -0.1636 | 0.6389 | |
| SRP008496 | FASTK | 10922 | RNAseq | -0.2178 | 0.3930 | |
| SRP064894 | FASTK | 10922 | RNAseq | 0.8018 | 0.0094 | |
| SRP133303 | FASTK | 10922 | RNAseq | -0.0095 | 0.9559 | |
| SRP159526 | FASTK | 10922 | RNAseq | 0.0628 | 0.7500 | |
| SRP193095 | FASTK | 10922 | RNAseq | -0.0977 | 0.2447 | |
| SRP219564 | FASTK | 10922 | RNAseq | 0.0953 | 0.7646 | |
| TCGA | FASTK | 10922 | RNAseq | 0.0310 | 0.5476 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FASTK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FASTK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FASTK | 10922 | 2 | 4 | 24 | |
| GSE20123 | FASTK | 10922 | 2 | 4 | 24 | |
| GSE43470 | FASTK | 10922 | 2 | 5 | 36 | |
| GSE46452 | FASTK | 10922 | 7 | 2 | 50 | |
| GSE47630 | FASTK | 10922 | 5 | 9 | 26 | |
| GSE54993 | FASTK | 10922 | 3 | 3 | 64 | |
| GSE54994 | FASTK | 10922 | 5 | 8 | 40 | |
| GSE60625 | FASTK | 10922 | 0 | 0 | 11 | |
| GSE74703 | FASTK | 10922 | 2 | 4 | 30 | |
| GSE74704 | FASTK | 10922 | 1 | 4 | 15 | |
| TCGA | FASTK | 10922 | 26 | 25 | 45 |
Total number of gains: 55; Total number of losses: 68; Total Number of normals: 365.
Somatic mutations of FASTK:
Generating mutation plots.
Highly correlated genes for FASTK:
Showing top 20/132 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FASTK | SHARPIN | 0.762617 | 3 | 0 | 3 |
| FASTK | LRCH4 | 0.760485 | 3 | 0 | 3 |
| FASTK | POLL | 0.755556 | 3 | 0 | 3 |
| FASTK | MICALL1 | 0.742682 | 3 | 0 | 3 |
| FASTK | AKR7A3 | 0.7283 | 3 | 0 | 3 |
| FASTK | ZNF687 | 0.72342 | 4 | 0 | 3 |
| FASTK | C7orf26 | 0.71986 | 3 | 0 | 3 |
| FASTK | CHMP6 | 0.715549 | 3 | 0 | 3 |
| FASTK | ZKSCAN2 | 0.713972 | 3 | 0 | 3 |
| FASTK | PRAMEF12 | 0.698081 | 3 | 0 | 3 |
| FASTK | DGKZ | 0.69741 | 4 | 0 | 3 |
| FASTK | PTGDS | 0.692489 | 3 | 0 | 3 |
| FASTK | CALCOCO1 | 0.686743 | 3 | 0 | 3 |
| FASTK | RUNDC3A | 0.685924 | 3 | 0 | 3 |
| FASTK | SCLY | 0.671801 | 3 | 0 | 3 |
| FASTK | CPNE6 | 0.671471 | 3 | 0 | 3 |
| FASTK | WNT2B | 0.665515 | 3 | 0 | 3 |
| FASTK | SURF2 | 0.664686 | 4 | 0 | 3 |
| FASTK | WDR60 | 0.659711 | 3 | 0 | 3 |
| FASTK | FURIN | 0.657201 | 4 | 0 | 3 |
For details and further investigation, click here
