| Full name: Rho GTPase activating protein 12 | Alias Symbol: FLJ20737|FLJ10971|FLJ21785 | ||
| Type: protein-coding gene | Cytoband: 10p11.22 | ||
| Entrez ID: 94134 | HGNC ID: HGNC:16348 | Ensembl Gene: ENSG00000165322 | OMIM ID: 610577 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP12 | 94134 | 207606_s_at | -0.0625 | 0.9019 | |
| GSE20347 | ARHGAP12 | 94134 | 207606_s_at | -0.1422 | 0.4734 | |
| GSE23400 | ARHGAP12 | 94134 | 207606_s_at | -0.1086 | 0.2175 | |
| GSE26886 | ARHGAP12 | 94134 | 207606_s_at | 0.3128 | 0.2768 | |
| GSE29001 | ARHGAP12 | 94134 | 207606_s_at | -0.2401 | 0.5333 | |
| GSE38129 | ARHGAP12 | 94134 | 207606_s_at | -0.2361 | 0.0692 | |
| GSE45670 | ARHGAP12 | 94134 | 207606_s_at | -0.4748 | 0.0009 | |
| GSE53622 | ARHGAP12 | 94134 | 87046 | -0.2124 | 0.0044 | |
| GSE53624 | ARHGAP12 | 94134 | 87046 | -0.2270 | 0.0000 | |
| GSE63941 | ARHGAP12 | 94134 | 207606_s_at | -0.4157 | 0.4077 | |
| GSE77861 | ARHGAP12 | 94134 | 207606_s_at | -0.0175 | 0.9748 | |
| GSE97050 | ARHGAP12 | 94134 | A_23_P149775 | -0.2532 | 0.3749 | |
| SRP007169 | ARHGAP12 | 94134 | RNAseq | -0.4554 | 0.3066 | |
| SRP008496 | ARHGAP12 | 94134 | RNAseq | -0.1393 | 0.5920 | |
| SRP064894 | ARHGAP12 | 94134 | RNAseq | -0.4844 | 0.0112 | |
| SRP133303 | ARHGAP12 | 94134 | RNAseq | -0.2553 | 0.1425 | |
| SRP159526 | ARHGAP12 | 94134 | RNAseq | -0.5939 | 0.0010 | |
| SRP193095 | ARHGAP12 | 94134 | RNAseq | -0.5954 | 0.0056 | |
| SRP219564 | ARHGAP12 | 94134 | RNAseq | -0.3564 | 0.1497 | |
| TCGA | ARHGAP12 | 94134 | RNAseq | -0.3371 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARHGAP12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP12 | 94134 | 5 | 7 | 18 | |
| GSE20123 | ARHGAP12 | 94134 | 5 | 6 | 19 | |
| GSE43470 | ARHGAP12 | 94134 | 4 | 3 | 36 | |
| GSE46452 | ARHGAP12 | 94134 | 1 | 14 | 44 | |
| GSE47630 | ARHGAP12 | 94134 | 5 | 15 | 20 | |
| GSE54993 | ARHGAP12 | 94134 | 9 | 0 | 61 | |
| GSE54994 | ARHGAP12 | 94134 | 3 | 8 | 42 | |
| GSE60625 | ARHGAP12 | 94134 | 0 | 0 | 11 | |
| GSE74703 | ARHGAP12 | 94134 | 2 | 2 | 32 | |
| GSE74704 | ARHGAP12 | 94134 | 0 | 5 | 15 | |
| TCGA | ARHGAP12 | 94134 | 18 | 24 | 54 |
Total number of gains: 52; Total number of losses: 84; Total Number of normals: 352.
Somatic mutations of ARHGAP12:
Generating mutation plots.
Highly correlated genes for ARHGAP12:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP12 | SLIT2 | 0.721918 | 3 | 0 | 3 |
| ARHGAP12 | ARL5B | 0.69308 | 3 | 0 | 3 |
| ARHGAP12 | PPP1R3B | 0.686955 | 3 | 0 | 3 |
| ARHGAP12 | C5orf51 | 0.686486 | 3 | 0 | 3 |
| ARHGAP12 | FBXO21 | 0.679741 | 3 | 0 | 3 |
| ARHGAP12 | PUM1 | 0.675806 | 3 | 0 | 3 |
| ARHGAP12 | FAN1 | 0.66891 | 3 | 0 | 3 |
| ARHGAP12 | ANKRD13C | 0.663051 | 4 | 0 | 3 |
| ARHGAP12 | RSRC2 | 0.661798 | 4 | 0 | 4 |
| ARHGAP12 | KIAA1586 | 0.660698 | 3 | 0 | 3 |
| ARHGAP12 | NUDT3 | 0.658058 | 3 | 0 | 3 |
| ARHGAP12 | WDR36 | 0.655191 | 4 | 0 | 4 |
| ARHGAP12 | THAP9-AS1 | 0.651099 | 3 | 0 | 3 |
| ARHGAP12 | DPY19L2 | 0.651032 | 3 | 0 | 3 |
| ARHGAP12 | RTTN | 0.646255 | 3 | 0 | 3 |
| ARHGAP12 | HOOK3 | 0.644452 | 4 | 0 | 3 |
| ARHGAP12 | KIAA0355 | 0.642505 | 3 | 0 | 3 |
| ARHGAP12 | AGTPBP1 | 0.636987 | 3 | 0 | 3 |
| ARHGAP12 | SELENBP1 | 0.63611 | 3 | 0 | 3 |
| ARHGAP12 | YTHDC2 | 0.635091 | 3 | 0 | 3 |
For details and further investigation, click here
