| Full name: ADP ribosylation factor like GTPase 5B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10p12.31 | ||
| Entrez ID: 221079 | HGNC ID: HGNC:23052 | Ensembl Gene: ENSG00000165997 | OMIM ID: 608909 |
| Drug and gene relationship at DGIdb | |||
Expression of ARL5B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARL5B | 221079 | 226345_at | 0.0326 | 0.9714 | |
| GSE26886 | ARL5B | 221079 | 226345_at | -0.3801 | 0.1031 | |
| GSE45670 | ARL5B | 221079 | 226345_at | 0.3574 | 0.0188 | |
| GSE53622 | ARL5B | 221079 | 8691 | 0.0737 | 0.4497 | |
| GSE53624 | ARL5B | 221079 | 8691 | 0.1577 | 0.0297 | |
| GSE63941 | ARL5B | 221079 | 226345_at | -0.4340 | 0.4365 | |
| GSE77861 | ARL5B | 221079 | 226345_at | 0.1959 | 0.4889 | |
| GSE97050 | ARL5B | 221079 | A_24_P943997 | 0.4238 | 0.1470 | |
| SRP007169 | ARL5B | 221079 | RNAseq | 0.3979 | 0.3758 | |
| SRP008496 | ARL5B | 221079 | RNAseq | 0.4927 | 0.0737 | |
| SRP064894 | ARL5B | 221079 | RNAseq | -0.1696 | 0.5989 | |
| SRP133303 | ARL5B | 221079 | RNAseq | 0.5173 | 0.0142 | |
| SRP159526 | ARL5B | 221079 | RNAseq | -0.1089 | 0.7245 | |
| SRP193095 | ARL5B | 221079 | RNAseq | -0.1997 | 0.1303 | |
| SRP219564 | ARL5B | 221079 | RNAseq | -0.3605 | 0.4664 | |
| TCGA | ARL5B | 221079 | RNAseq | 0.1317 | 0.0835 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARL5B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARL5B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARL5B | 221079 | 3 | 8 | 19 | |
| GSE20123 | ARL5B | 221079 | 3 | 7 | 20 | |
| GSE43470 | ARL5B | 221079 | 3 | 3 | 37 | |
| GSE46452 | ARL5B | 221079 | 1 | 14 | 44 | |
| GSE47630 | ARL5B | 221079 | 5 | 15 | 20 | |
| GSE54993 | ARL5B | 221079 | 10 | 0 | 60 | |
| GSE54994 | ARL5B | 221079 | 4 | 8 | 41 | |
| GSE60625 | ARL5B | 221079 | 0 | 0 | 11 | |
| GSE74703 | ARL5B | 221079 | 2 | 2 | 32 | |
| GSE74704 | ARL5B | 221079 | 0 | 6 | 14 | |
| TCGA | ARL5B | 221079 | 18 | 25 | 53 |
Total number of gains: 49; Total number of losses: 88; Total Number of normals: 351.
Somatic mutations of ARL5B:
Generating mutation plots.
Highly correlated genes for ARL5B:
Showing top 20/114 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARL5B | NBN | 0.762665 | 3 | 0 | 3 |
| ARL5B | ANKIB1 | 0.760511 | 3 | 0 | 3 |
| ARL5B | SCAI | 0.756262 | 3 | 0 | 3 |
| ARL5B | PPP6R3 | 0.755357 | 3 | 0 | 3 |
| ARL5B | TUBE1 | 0.753244 | 3 | 0 | 3 |
| ARL5B | RBM17 | 0.744052 | 3 | 0 | 3 |
| ARL5B | ATF1 | 0.742807 | 3 | 0 | 3 |
| ARL5B | SPRED1 | 0.742007 | 3 | 0 | 3 |
| ARL5B | SLC6A15 | 0.735919 | 3 | 0 | 3 |
| ARL5B | USP45 | 0.733868 | 3 | 0 | 3 |
| ARL5B | CXCL2 | 0.733549 | 3 | 0 | 3 |
| ARL5B | USP34 | 0.733046 | 3 | 0 | 3 |
| ARL5B | ZDHHC17 | 0.732457 | 3 | 0 | 3 |
| ARL5B | DLG5 | 0.729181 | 3 | 0 | 3 |
| ARL5B | REEP3 | 0.724314 | 3 | 0 | 3 |
| ARL5B | TAS2R19 | 0.722507 | 3 | 0 | 3 |
| ARL5B | SIKE1 | 0.721567 | 4 | 0 | 3 |
| ARL5B | MTX2 | 0.718362 | 3 | 0 | 3 |
| ARL5B | SUN1 | 0.713948 | 3 | 0 | 3 |
| ARL5B | ANKRD50 | 0.710803 | 3 | 0 | 3 |
For details and further investigation, click here
