| Full name: YTH domain containing 2 | Alias Symbol: FLJ2194|FLJ10053|DKFZp564A186 | ||
| Type: protein-coding gene | Cytoband: 5q22.2 | ||
| Entrez ID: 64848 | HGNC ID: HGNC:24721 | Ensembl Gene: ENSG00000047188 | OMIM ID: 616530 |
| Drug and gene relationship at DGIdb | |||
Expression of YTHDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YTHDC2 | 64848 | 213077_at | -0.6074 | 0.1209 | |
| GSE20347 | YTHDC2 | 64848 | 213077_at | -0.8416 | 0.0000 | |
| GSE23400 | YTHDC2 | 64848 | 213077_at | -0.3385 | 0.0002 | |
| GSE26886 | YTHDC2 | 64848 | 213077_at | -0.7861 | 0.0009 | |
| GSE29001 | YTHDC2 | 64848 | 213077_at | -0.3614 | 0.2032 | |
| GSE38129 | YTHDC2 | 64848 | 213077_at | -0.6650 | 0.0000 | |
| GSE45670 | YTHDC2 | 64848 | 213077_at | -0.3928 | 0.0176 | |
| GSE53622 | YTHDC2 | 64848 | 6325 | -0.7400 | 0.0000 | |
| GSE53624 | YTHDC2 | 64848 | 6325 | -0.7306 | 0.0000 | |
| GSE63941 | YTHDC2 | 64848 | 213077_at | -0.9438 | 0.1471 | |
| GSE77861 | YTHDC2 | 64848 | 213077_at | -0.7028 | 0.0285 | |
| GSE97050 | YTHDC2 | 64848 | A_33_P3420747 | -0.3176 | 0.2050 | |
| SRP007169 | YTHDC2 | 64848 | RNAseq | -0.9137 | 0.0033 | |
| SRP008496 | YTHDC2 | 64848 | RNAseq | -0.6260 | 0.0072 | |
| SRP064894 | YTHDC2 | 64848 | RNAseq | -0.4686 | 0.0814 | |
| SRP133303 | YTHDC2 | 64848 | RNAseq | -0.1610 | 0.1751 | |
| SRP159526 | YTHDC2 | 64848 | RNAseq | -0.7926 | 0.0004 | |
| SRP193095 | YTHDC2 | 64848 | RNAseq | -0.6136 | 0.0000 | |
| SRP219564 | YTHDC2 | 64848 | RNAseq | -0.4496 | 0.1706 | |
| TCGA | YTHDC2 | 64848 | RNAseq | -0.1385 | 0.0054 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by YTHDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YTHDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YTHDC2 | 64848 | 1 | 13 | 16 | |
| GSE20123 | YTHDC2 | 64848 | 1 | 13 | 16 | |
| GSE43470 | YTHDC2 | 64848 | 3 | 8 | 32 | |
| GSE46452 | YTHDC2 | 64848 | 0 | 28 | 31 | |
| GSE47630 | YTHDC2 | 64848 | 0 | 21 | 19 | |
| GSE54993 | YTHDC2 | 64848 | 9 | 1 | 60 | |
| GSE54994 | YTHDC2 | 64848 | 1 | 17 | 35 | |
| GSE60625 | YTHDC2 | 64848 | 0 | 0 | 11 | |
| GSE74703 | YTHDC2 | 64848 | 2 | 6 | 28 | |
| GSE74704 | YTHDC2 | 64848 | 1 | 7 | 12 | |
| TCGA | YTHDC2 | 64848 | 2 | 41 | 53 |
Total number of gains: 20; Total number of losses: 155; Total Number of normals: 313.
Somatic mutations of YTHDC2:
Generating mutation plots.
Highly correlated genes for YTHDC2:
Showing top 20/1391 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YTHDC2 | COG6 | 0.782216 | 4 | 0 | 4 |
| YTHDC2 | CA13 | 0.776382 | 3 | 0 | 3 |
| YTHDC2 | DMXL1 | 0.772558 | 13 | 0 | 12 |
| YTHDC2 | OR7A10 | 0.755409 | 4 | 0 | 4 |
| YTHDC2 | PPP1R3B | 0.741472 | 4 | 0 | 3 |
| YTHDC2 | BIRC6 | 0.738225 | 3 | 0 | 3 |
| YTHDC2 | RBM20 | 0.736272 | 4 | 0 | 4 |
| YTHDC2 | TRIP11 | 0.731114 | 4 | 0 | 4 |
| YTHDC2 | SLC10A5 | 0.727137 | 3 | 0 | 3 |
| YTHDC2 | CCNYL1 | 0.726775 | 5 | 0 | 5 |
| YTHDC2 | C7orf57 | 0.722111 | 4 | 0 | 4 |
| YTHDC2 | COMMD1 | 0.719616 | 4 | 0 | 3 |
| YTHDC2 | NUDT12 | 0.715669 | 6 | 0 | 5 |
| YTHDC2 | SLC7A4 | 0.713337 | 5 | 0 | 5 |
| YTHDC2 | DLG2 | 0.71113 | 9 | 0 | 9 |
| YTHDC2 | ITPR2 | 0.710855 | 10 | 0 | 9 |
| YTHDC2 | KCTD6 | 0.710388 | 7 | 0 | 7 |
| YTHDC2 | FNIP1 | 0.708595 | 4 | 0 | 4 |
| YTHDC2 | FAM174A | 0.70821 | 8 | 0 | 7 |
| YTHDC2 | SLC46A2 | 0.705005 | 7 | 0 | 5 |
For details and further investigation, click here
