| Full name: KIAA1586 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p12.1 | ||
| Entrez ID: 57691 | HGNC ID: HGNC:21360 | Ensembl Gene: ENSG00000168116 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KIAA1586:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIAA1586 | 57691 | 231869_at | 0.1495 | 0.5711 | |
| GSE26886 | KIAA1586 | 57691 | 231869_at | 0.6617 | 0.0016 | |
| GSE45670 | KIAA1586 | 57691 | 231869_at | 0.1524 | 0.5965 | |
| GSE53622 | KIAA1586 | 57691 | 13479 | -0.0222 | 0.8852 | |
| GSE53624 | KIAA1586 | 57691 | 13479 | 0.5102 | 0.0009 | |
| GSE63941 | KIAA1586 | 57691 | 231869_at | -0.9841 | 0.0785 | |
| GSE77861 | KIAA1586 | 57691 | 231869_at | 0.1044 | 0.6270 | |
| GSE97050 | KIAA1586 | 57691 | A_24_P101047 | -0.3280 | 0.2722 | |
| SRP007169 | KIAA1586 | 57691 | RNAseq | 1.5883 | 0.0166 | |
| SRP008496 | KIAA1586 | 57691 | RNAseq | 1.9510 | 0.0000 | |
| SRP064894 | KIAA1586 | 57691 | RNAseq | 0.4204 | 0.0399 | |
| SRP133303 | KIAA1586 | 57691 | RNAseq | 0.0130 | 0.9529 | |
| SRP159526 | KIAA1586 | 57691 | RNAseq | 0.3443 | 0.1702 | |
| SRP193095 | KIAA1586 | 57691 | RNAseq | -0.0709 | 0.6716 | |
| SRP219564 | KIAA1586 | 57691 | RNAseq | 0.2504 | 0.4551 | |
| TCGA | KIAA1586 | 57691 | RNAseq | 0.1982 | 0.0262 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by KIAA1586 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIAA1586:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIAA1586 | 57691 | 8 | 2 | 20 | |
| GSE20123 | KIAA1586 | 57691 | 8 | 2 | 20 | |
| GSE43470 | KIAA1586 | 57691 | 4 | 0 | 39 | |
| GSE46452 | KIAA1586 | 57691 | 2 | 10 | 47 | |
| GSE47630 | KIAA1586 | 57691 | 7 | 5 | 28 | |
| GSE54993 | KIAA1586 | 57691 | 3 | 2 | 65 | |
| GSE54994 | KIAA1586 | 57691 | 9 | 4 | 40 | |
| GSE60625 | KIAA1586 | 57691 | 0 | 1 | 10 | |
| GSE74703 | KIAA1586 | 57691 | 4 | 0 | 32 | |
| GSE74704 | KIAA1586 | 57691 | 4 | 1 | 15 | |
| TCGA | KIAA1586 | 57691 | 23 | 10 | 63 |
Total number of gains: 72; Total number of losses: 37; Total Number of normals: 379.
Somatic mutations of KIAA1586:
Generating mutation plots.
Highly correlated genes for KIAA1586:
Showing top 20/616 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIAA1586 | SS18 | 0.775293 | 3 | 0 | 3 |
| KIAA1586 | DMTF1 | 0.771558 | 3 | 0 | 3 |
| KIAA1586 | GCSH | 0.769699 | 3 | 0 | 3 |
| KIAA1586 | TNS3 | 0.76336 | 4 | 0 | 4 |
| KIAA1586 | NUDT15 | 0.762742 | 3 | 0 | 3 |
| KIAA1586 | DROSHA | 0.753183 | 3 | 0 | 3 |
| KIAA1586 | PPTC7 | 0.741761 | 3 | 0 | 3 |
| KIAA1586 | TATDN1 | 0.740554 | 5 | 0 | 5 |
| KIAA1586 | TADA2A | 0.738045 | 3 | 0 | 3 |
| KIAA1586 | GNPDA1 | 0.731596 | 3 | 0 | 3 |
| KIAA1586 | COQ3 | 0.729701 | 3 | 0 | 3 |
| KIAA1586 | ARMC10 | 0.728846 | 3 | 0 | 3 |
| KIAA1586 | NHS | 0.723349 | 3 | 0 | 3 |
| KIAA1586 | LANCL2 | 0.723145 | 3 | 0 | 3 |
| KIAA1586 | C7orf50 | 0.723073 | 3 | 0 | 3 |
| KIAA1586 | NEDD9 | 0.718054 | 4 | 0 | 4 |
| KIAA1586 | PET117 | 0.715516 | 3 | 0 | 3 |
| KIAA1586 | EXTL3 | 0.715304 | 3 | 0 | 3 |
| KIAA1586 | C17orf75 | 0.713025 | 4 | 0 | 4 |
| KIAA1586 | PITX2 | 0.712979 | 3 | 0 | 3 |
For details and further investigation, click here
