| Full name: F-box protein 21 | Alias Symbol: FBX21|KIAA0875 | ||
| Type: protein-coding gene | Cytoband: 12q24.22 | ||
| Entrez ID: 23014 | HGNC ID: HGNC:13592 | Ensembl Gene: ENSG00000135108 | OMIM ID: 609095 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO21 | 23014 | 212229_s_at | 0.2952 | 0.5655 | |
| GSE20347 | FBXO21 | 23014 | 212229_s_at | 0.4101 | 0.0011 | |
| GSE23400 | FBXO21 | 23014 | 212229_s_at | 0.2140 | 0.0299 | |
| GSE26886 | FBXO21 | 23014 | 212231_at | 0.5189 | 0.0271 | |
| GSE29001 | FBXO21 | 23014 | 212231_at | 0.4794 | 0.0343 | |
| GSE38129 | FBXO21 | 23014 | 212229_s_at | 0.2097 | 0.0984 | |
| GSE45670 | FBXO21 | 23014 | 212229_s_at | -0.2316 | 0.1096 | |
| GSE53622 | FBXO21 | 23014 | 5002 | 0.1197 | 0.0714 | |
| GSE53624 | FBXO21 | 23014 | 5002 | 0.2600 | 0.0001 | |
| GSE63941 | FBXO21 | 23014 | 212229_s_at | 0.7250 | 0.0222 | |
| GSE77861 | FBXO21 | 23014 | 212231_at | 0.5263 | 0.0223 | |
| GSE97050 | FBXO21 | 23014 | A_23_P53736 | -0.1958 | 0.3621 | |
| SRP007169 | FBXO21 | 23014 | RNAseq | 0.8845 | 0.0153 | |
| SRP008496 | FBXO21 | 23014 | RNAseq | 0.8380 | 0.0000 | |
| SRP064894 | FBXO21 | 23014 | RNAseq | -0.0674 | 0.5693 | |
| SRP133303 | FBXO21 | 23014 | RNAseq | 0.0605 | 0.5603 | |
| SRP159526 | FBXO21 | 23014 | RNAseq | 0.3727 | 0.0863 | |
| SRP193095 | FBXO21 | 23014 | RNAseq | 0.0154 | 0.8781 | |
| SRP219564 | FBXO21 | 23014 | RNAseq | -0.2250 | 0.3811 | |
| TCGA | FBXO21 | 23014 | RNAseq | -0.1391 | 0.0024 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBXO21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO21 | 23014 | 4 | 3 | 23 | |
| GSE20123 | FBXO21 | 23014 | 3 | 3 | 24 | |
| GSE43470 | FBXO21 | 23014 | 2 | 0 | 41 | |
| GSE46452 | FBXO21 | 23014 | 9 | 1 | 49 | |
| GSE47630 | FBXO21 | 23014 | 9 | 3 | 28 | |
| GSE54993 | FBXO21 | 23014 | 0 | 5 | 65 | |
| GSE54994 | FBXO21 | 23014 | 6 | 5 | 42 | |
| GSE60625 | FBXO21 | 23014 | 0 | 0 | 11 | |
| GSE74703 | FBXO21 | 23014 | 2 | 0 | 34 | |
| GSE74704 | FBXO21 | 23014 | 2 | 2 | 16 | |
| TCGA | FBXO21 | 23014 | 21 | 10 | 65 |
Total number of gains: 58; Total number of losses: 32; Total Number of normals: 398.
Somatic mutations of FBXO21:
Generating mutation plots.
Highly correlated genes for FBXO21:
Showing top 20/1277 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO21 | ATXN1L | 0.825897 | 3 | 0 | 3 |
| FBXO21 | ZDHHC7 | 0.778838 | 4 | 0 | 4 |
| FBXO21 | CYB5D1 | 0.776193 | 3 | 0 | 3 |
| FBXO21 | BOD1 | 0.774306 | 4 | 0 | 3 |
| FBXO21 | MSI2 | 0.755623 | 4 | 0 | 4 |
| FBXO21 | UEVLD | 0.753208 | 3 | 0 | 3 |
| FBXO21 | ISY1 | 0.750577 | 3 | 0 | 3 |
| FBXO21 | TTC30B | 0.747819 | 4 | 0 | 4 |
| FBXO21 | KIAA1257 | 0.734206 | 3 | 0 | 3 |
| FBXO21 | CRLS1 | 0.732597 | 3 | 0 | 3 |
| FBXO21 | C8orf37 | 0.724314 | 3 | 0 | 3 |
| FBXO21 | IWS1 | 0.721332 | 3 | 0 | 3 |
| FBXO21 | PMF1 | 0.719679 | 3 | 0 | 3 |
| FBXO21 | HPS3 | 0.718515 | 4 | 0 | 4 |
| FBXO21 | ZNF121 | 0.713876 | 3 | 0 | 3 |
| FBXO21 | FGGY | 0.713865 | 3 | 0 | 3 |
| FBXO21 | SMAD1 | 0.709135 | 4 | 0 | 4 |
| FBXO21 | CNOT10 | 0.708172 | 3 | 0 | 3 |
| FBXO21 | PUF60 | 0.706365 | 5 | 0 | 5 |
| FBXO21 | LIN9 | 0.705587 | 4 | 0 | 4 |
For details and further investigation, click here
