| Full name: WD repeat domain 36 | Alias Symbol: TA-WDRP|UTP21 | ||
| Type: protein-coding gene | Cytoband: 5q22.1 | ||
| Entrez ID: 134430 | HGNC ID: HGNC:30696 | Ensembl Gene: ENSG00000134987 | OMIM ID: 609669 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of WDR36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR36 | 134430 | 226180_at | -0.0200 | 0.9806 | |
| GSE26886 | WDR36 | 134430 | 226180_at | 0.0702 | 0.8222 | |
| GSE45670 | WDR36 | 134430 | 226180_at | -0.1665 | 0.3483 | |
| GSE53622 | WDR36 | 134430 | 18045 | -0.1780 | 0.0526 | |
| GSE53624 | WDR36 | 134430 | 23908 | -0.1713 | 0.0247 | |
| GSE63941 | WDR36 | 134430 | 226180_at | -1.8080 | 0.0084 | |
| GSE77861 | WDR36 | 134430 | 226180_at | 0.0370 | 0.9022 | |
| GSE97050 | WDR36 | 134430 | A_24_P106357 | -0.0632 | 0.8242 | |
| SRP007169 | WDR36 | 134430 | RNAseq | 0.4084 | 0.3273 | |
| SRP008496 | WDR36 | 134430 | RNAseq | 0.5432 | 0.0277 | |
| SRP064894 | WDR36 | 134430 | RNAseq | 0.2895 | 0.1686 | |
| SRP133303 | WDR36 | 134430 | RNAseq | 0.6362 | 0.0088 | |
| SRP159526 | WDR36 | 134430 | RNAseq | -0.3968 | 0.0622 | |
| SRP193095 | WDR36 | 134430 | RNAseq | -0.1778 | 0.1347 | |
| SRP219564 | WDR36 | 134430 | RNAseq | -0.0469 | 0.9251 | |
| TCGA | WDR36 | 134430 | RNAseq | 0.0745 | 0.1333 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by WDR36 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR36 | 134430 | 1 | 13 | 16 | |
| GSE20123 | WDR36 | 134430 | 1 | 13 | 16 | |
| GSE43470 | WDR36 | 134430 | 3 | 8 | 32 | |
| GSE46452 | WDR36 | 134430 | 0 | 28 | 31 | |
| GSE47630 | WDR36 | 134430 | 0 | 21 | 19 | |
| GSE54993 | WDR36 | 134430 | 9 | 1 | 60 | |
| GSE54994 | WDR36 | 134430 | 1 | 17 | 35 | |
| GSE60625 | WDR36 | 134430 | 0 | 0 | 11 | |
| GSE74703 | WDR36 | 134430 | 2 | 6 | 28 | |
| GSE74704 | WDR36 | 134430 | 1 | 7 | 12 | |
| TCGA | WDR36 | 134430 | 2 | 41 | 53 |
Total number of gains: 20; Total number of losses: 155; Total Number of normals: 313.
Somatic mutations of WDR36:
Generating mutation plots.
Highly correlated genes for WDR36:
Showing top 20/389 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR36 | CDC123 | 0.81271 | 3 | 0 | 3 |
| WDR36 | MTPAP | 0.803048 | 3 | 0 | 3 |
| WDR36 | UBR3 | 0.78828 | 3 | 0 | 3 |
| WDR36 | RAPGEF2 | 0.768608 | 3 | 0 | 3 |
| WDR36 | SERPINB8 | 0.763963 | 3 | 0 | 3 |
| WDR36 | CNOT7 | 0.759198 | 3 | 0 | 3 |
| WDR36 | PDZD8 | 0.755438 | 3 | 0 | 3 |
| WDR36 | RB1 | 0.744955 | 3 | 0 | 3 |
| WDR36 | ACTR2 | 0.73503 | 3 | 0 | 3 |
| WDR36 | KIF16B | 0.734002 | 3 | 0 | 3 |
| WDR36 | HOOK3 | 0.733044 | 4 | 0 | 4 |
| WDR36 | APPL2 | 0.73301 | 3 | 0 | 3 |
| WDR36 | RSRC2 | 0.731615 | 3 | 0 | 3 |
| WDR36 | CNIH1 | 0.728632 | 3 | 0 | 3 |
| WDR36 | SNX18 | 0.728229 | 3 | 0 | 3 |
| WDR36 | WDR20 | 0.725585 | 3 | 0 | 3 |
| WDR36 | DPH5 | 0.72279 | 3 | 0 | 3 |
| WDR36 | THAP2 | 0.72213 | 4 | 0 | 3 |
| WDR36 | PCSK5 | 0.721747 | 3 | 0 | 3 |
| WDR36 | MLLT10 | 0.720982 | 4 | 0 | 4 |
For details and further investigation, click here
