| Full name: rotatin | Alias Symbol: DKFZP434G145 | ||
| Type: protein-coding gene | Cytoband: 18q22.1 | ||
| Entrez ID: 25914 | HGNC ID: HGNC:18654 | Ensembl Gene: ENSG00000176225 | OMIM ID: 610436 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RTTN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTTN | 25914 | 227072_at | 1.0671 | 0.1683 | |
| GSE26886 | RTTN | 25914 | 227072_at | 1.4975 | 0.0000 | |
| GSE45670 | RTTN | 25914 | 227072_at | 0.4282 | 0.2227 | |
| GSE53622 | RTTN | 25914 | 9992 | 0.7453 | 0.0001 | |
| GSE53624 | RTTN | 25914 | 9992 | 0.9083 | 0.0000 | |
| GSE63941 | RTTN | 25914 | 227072_at | 0.0943 | 0.8921 | |
| GSE77861 | RTTN | 25914 | 227072_at | 0.5774 | 0.0860 | |
| GSE97050 | RTTN | 25914 | A_24_P108301 | 0.0056 | 0.9846 | |
| SRP007169 | RTTN | 25914 | RNAseq | 0.1897 | 0.6406 | |
| SRP008496 | RTTN | 25914 | RNAseq | 0.3350 | 0.2318 | |
| SRP064894 | RTTN | 25914 | RNAseq | 0.4654 | 0.0312 | |
| SRP133303 | RTTN | 25914 | RNAseq | 0.3301 | 0.1084 | |
| SRP159526 | RTTN | 25914 | RNAseq | 0.4035 | 0.2621 | |
| SRP193095 | RTTN | 25914 | RNAseq | 0.4771 | 0.0000 | |
| SRP219564 | RTTN | 25914 | RNAseq | 0.4834 | 0.0502 | |
| TCGA | RTTN | 25914 | RNAseq | 0.2042 | 0.0103 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RTTN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTTN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTTN | 25914 | 0 | 10 | 20 | |
| GSE20123 | RTTN | 25914 | 0 | 10 | 20 | |
| GSE43470 | RTTN | 25914 | 0 | 8 | 35 | |
| GSE46452 | RTTN | 25914 | 1 | 26 | 32 | |
| GSE47630 | RTTN | 25914 | 5 | 21 | 14 | |
| GSE54993 | RTTN | 25914 | 9 | 0 | 61 | |
| GSE54994 | RTTN | 25914 | 1 | 19 | 33 | |
| GSE60625 | RTTN | 25914 | 0 | 4 | 7 | |
| GSE74703 | RTTN | 25914 | 0 | 8 | 28 | |
| GSE74704 | RTTN | 25914 | 0 | 8 | 12 | |
| TCGA | RTTN | 25914 | 5 | 49 | 42 |
Total number of gains: 21; Total number of losses: 163; Total Number of normals: 304.
Somatic mutations of RTTN:
Generating mutation plots.
Highly correlated genes for RTTN:
Showing top 20/1109 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTTN | MMP15 | 0.815054 | 3 | 0 | 3 |
| RTTN | AGPAT5 | 0.765208 | 3 | 0 | 3 |
| RTTN | CCT5 | 0.756622 | 3 | 0 | 3 |
| RTTN | ZNF200 | 0.746312 | 3 | 0 | 3 |
| RTTN | DNM1L | 0.735455 | 3 | 0 | 3 |
| RTTN | PTCD3 | 0.7185 | 3 | 0 | 3 |
| RTTN | MRPS17 | 0.713353 | 4 | 0 | 4 |
| RTTN | CARD10 | 0.705822 | 4 | 0 | 4 |
| RTTN | INTS10 | 0.705214 | 3 | 0 | 3 |
| RTTN | SEMA3A | 0.697627 | 4 | 0 | 3 |
| RTTN | SLC25A24 | 0.689457 | 4 | 0 | 4 |
| RTTN | CWF19L1 | 0.686864 | 5 | 0 | 5 |
| RTTN | PON3 | 0.686057 | 3 | 0 | 3 |
| RTTN | PRIM2 | 0.683884 | 6 | 0 | 6 |
| RTTN | THOC5 | 0.68387 | 5 | 0 | 5 |
| RTTN | DOCK11 | 0.683859 | 3 | 0 | 3 |
| RTTN | ENPEP | 0.68324 | 3 | 0 | 3 |
| RTTN | NEDD9 | 0.682912 | 3 | 0 | 3 |
| RTTN | REV3L | 0.6818 | 3 | 0 | 3 |
| RTTN | ITGAV | 0.681505 | 5 | 0 | 5 |
For details and further investigation, click here
