| Full name: nudix hydrolase 3 | Alias Symbol: DIPP | ||
| Type: protein-coding gene | Cytoband: 6p21.31 | ||
| Entrez ID: 11165 | HGNC ID: HGNC:8050 | Ensembl Gene: ENSG00000272325 | OMIM ID: 609228 |
| Drug and gene relationship at DGIdb | |||
Expression of NUDT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUDT3 | 11165 | 212608_s_at | 0.2299 | 0.6051 | |
| GSE20347 | NUDT3 | 11165 | 212608_s_at | 0.0255 | 0.8899 | |
| GSE23400 | NUDT3 | 11165 | 211976_at | -0.1725 | 0.0009 | |
| GSE26886 | NUDT3 | 11165 | 212608_s_at | -0.0236 | 0.9244 | |
| GSE29001 | NUDT3 | 11165 | 212608_s_at | -0.1749 | 0.3884 | |
| GSE38129 | NUDT3 | 11165 | 212608_s_at | -0.1938 | 0.1806 | |
| GSE45670 | NUDT3 | 11165 | 212608_s_at | -0.4333 | 0.0052 | |
| GSE53622 | NUDT3 | 11165 | 7610 | -0.3675 | 0.0000 | |
| GSE53624 | NUDT3 | 11165 | 7610 | -0.0015 | 0.9793 | |
| GSE63941 | NUDT3 | 11165 | 212608_s_at | -0.0201 | 0.9699 | |
| GSE77861 | NUDT3 | 11165 | 212608_s_at | 0.0186 | 0.9445 | |
| GSE97050 | NUDT3 | 11165 | A_23_P93389 | -0.5495 | 0.1453 | |
| SRP007169 | NUDT3 | 11165 | RNAseq | 1.0052 | 0.0298 | |
| SRP008496 | NUDT3 | 11165 | RNAseq | 1.0695 | 0.0002 | |
| SRP064894 | NUDT3 | 11165 | RNAseq | -0.0460 | 0.7200 | |
| SRP133303 | NUDT3 | 11165 | RNAseq | -0.3625 | 0.0044 | |
| SRP159526 | NUDT3 | 11165 | RNAseq | -0.0265 | 0.9298 | |
| SRP193095 | NUDT3 | 11165 | RNAseq | -0.0114 | 0.9158 | |
| SRP219564 | NUDT3 | 11165 | RNAseq | 0.0392 | 0.8937 | |
| TCGA | NUDT3 | 11165 | RNAseq | 0.1761 | 0.0017 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NUDT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUDT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUDT3 | 11165 | 5 | 0 | 25 | |
| GSE20123 | NUDT3 | 11165 | 5 | 0 | 25 | |
| GSE43470 | NUDT3 | 11165 | 6 | 1 | 36 | |
| GSE46452 | NUDT3 | 11165 | 2 | 9 | 48 | |
| GSE47630 | NUDT3 | 11165 | 8 | 4 | 28 | |
| GSE54993 | NUDT3 | 11165 | 3 | 1 | 66 | |
| GSE54994 | NUDT3 | 11165 | 11 | 4 | 38 | |
| GSE60625 | NUDT3 | 11165 | 1 | 0 | 10 | |
| GSE74703 | NUDT3 | 11165 | 5 | 0 | 31 | |
| GSE74704 | NUDT3 | 11165 | 2 | 0 | 18 | |
| TCGA | NUDT3 | 11165 | 16 | 15 | 65 |
Total number of gains: 64; Total number of losses: 34; Total Number of normals: 390.
Somatic mutations of NUDT3:
Generating mutation plots.
Highly correlated genes for NUDT3:
Showing top 20/414 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUDT3 | GZF1 | 0.776491 | 3 | 0 | 3 |
| NUDT3 | PCID2 | 0.776274 | 3 | 0 | 3 |
| NUDT3 | POMT1 | 0.772767 | 3 | 0 | 3 |
| NUDT3 | TMEM167B | 0.758994 | 3 | 0 | 3 |
| NUDT3 | KBTBD7 | 0.751901 | 3 | 0 | 3 |
| NUDT3 | TBRG1 | 0.75181 | 3 | 0 | 3 |
| NUDT3 | MACROD2 | 0.735295 | 3 | 0 | 3 |
| NUDT3 | ZSCAN21 | 0.721957 | 3 | 0 | 3 |
| NUDT3 | ADNP | 0.717007 | 3 | 0 | 3 |
| NUDT3 | TMEM170B | 0.710841 | 5 | 0 | 5 |
| NUDT3 | GNPDA2 | 0.709251 | 3 | 0 | 3 |
| NUDT3 | GNL3 | 0.706407 | 3 | 0 | 3 |
| NUDT3 | BTG1 | 0.704889 | 3 | 0 | 3 |
| NUDT3 | BTN3A2 | 0.701896 | 3 | 0 | 3 |
| NUDT3 | RAB9B | 0.701171 | 3 | 0 | 3 |
| NUDT3 | PDS5B | 0.699421 | 3 | 0 | 3 |
| NUDT3 | DCP2 | 0.698485 | 3 | 0 | 3 |
| NUDT3 | USP20 | 0.697482 | 4 | 0 | 3 |
| NUDT3 | ZNF518B | 0.696794 | 3 | 0 | 3 |
| NUDT3 | MLLT10 | 0.692944 | 3 | 0 | 3 |
For details and further investigation, click here
