| Full name: dpy-19 like 2 | Alias Symbol: FLJ32949|SPATA34 | ||
| Type: protein-coding gene | Cytoband: 12q14.2 | ||
| Entrez ID: 283417 | HGNC ID: HGNC:19414 | Ensembl Gene: ENSG00000177990 | OMIM ID: 613893 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DPY19L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPY19L2 | 283417 | 238784_at | 0.2392 | 0.6496 | |
| GSE26886 | DPY19L2 | 283417 | 238784_at | 1.1470 | 0.0037 | |
| GSE45670 | DPY19L2 | 283417 | 230158_at | -1.0549 | 0.0006 | |
| GSE53622 | DPY19L2 | 283417 | 69202 | -0.2559 | 0.1100 | |
| GSE53624 | DPY19L2 | 283417 | 69202 | -0.0720 | 0.6052 | |
| GSE63941 | DPY19L2 | 283417 | 238784_at | -0.9643 | 0.1490 | |
| GSE77861 | DPY19L2 | 283417 | 238784_at | 0.2474 | 0.0761 | |
| GSE97050 | DPY19L2 | A_21_P0013189 | -0.2806 | 0.3463 | ||
| SRP064894 | DPY19L2 | 283417 | RNAseq | -0.1515 | 0.7037 | |
| SRP133303 | DPY19L2 | 283417 | RNAseq | -0.7446 | 0.0090 | |
| SRP159526 | DPY19L2 | 283417 | RNAseq | 0.2723 | 0.6549 | |
| SRP193095 | DPY19L2 | 283417 | RNAseq | 0.9149 | 0.0001 | |
| SRP219564 | DPY19L2 | 283417 | RNAseq | -0.5151 | 0.4537 | |
| TCGA | DPY19L2 | 283417 | RNAseq | -0.6055 | 0.0538 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by DPY19L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPY19L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPY19L2 | 283417 | 3 | 1 | 26 | |
| GSE20123 | DPY19L2 | 283417 | 3 | 1 | 26 | |
| GSE43470 | DPY19L2 | 283417 | 4 | 0 | 39 | |
| GSE46452 | DPY19L2 | 283417 | 10 | 0 | 49 | |
| GSE47630 | DPY19L2 | 283417 | 10 | 2 | 28 | |
| GSE54993 | DPY19L2 | 283417 | 0 | 5 | 65 | |
| GSE54994 | DPY19L2 | 283417 | 6 | 1 | 46 | |
| GSE60625 | DPY19L2 | 283417 | 0 | 0 | 11 | |
| GSE74703 | DPY19L2 | 283417 | 4 | 0 | 32 | |
| GSE74704 | DPY19L2 | 283417 | 2 | 1 | 17 | |
| TCGA | DPY19L2 | 283417 | 18 | 9 | 69 |
Total number of gains: 60; Total number of losses: 20; Total Number of normals: 408.
Somatic mutations of DPY19L2:
Generating mutation plots.
Highly correlated genes for DPY19L2:
Showing top 20/354 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPY19L2 | FGF12 | 0.795146 | 3 | 0 | 3 |
| DPY19L2 | UVRAG | 0.7624 | 3 | 0 | 3 |
| DPY19L2 | WDR81 | 0.749555 | 3 | 0 | 3 |
| DPY19L2 | ZNF280C | 0.736417 | 3 | 0 | 3 |
| DPY19L2 | SAT2 | 0.725255 | 3 | 0 | 3 |
| DPY19L2 | MED17 | 0.71988 | 3 | 0 | 3 |
| DPY19L2 | LUC7L2 | 0.71522 | 3 | 0 | 3 |
| DPY19L2 | CYP20A1 | 0.715026 | 4 | 0 | 3 |
| DPY19L2 | TCEA2 | 0.713419 | 3 | 0 | 3 |
| DPY19L2 | BDNF | 0.707253 | 4 | 0 | 3 |
| DPY19L2 | FBXL4 | 0.702221 | 3 | 0 | 3 |
| DPY19L2 | MRAS | 0.701073 | 3 | 0 | 3 |
| DPY19L2 | TMEM97 | 0.699577 | 3 | 0 | 3 |
| DPY19L2 | TLN2 | 0.699117 | 3 | 0 | 3 |
| DPY19L2 | PRKAR2B | 0.697789 | 5 | 0 | 4 |
| DPY19L2 | C2orf69 | 0.696892 | 3 | 0 | 3 |
| DPY19L2 | PLCB4 | 0.694084 | 6 | 0 | 6 |
| DPY19L2 | NOM1 | 0.6923 | 3 | 0 | 3 |
| DPY19L2 | RFXAP | 0.691886 | 3 | 0 | 3 |
| DPY19L2 | KLHL13 | 0.69173 | 3 | 0 | 3 |
For details and further investigation, click here
