| Full name: Rho guanine nucleotide exchange factor 17 | Alias Symbol: TEM4|KIAA0337|p164-RhoGEF | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 9828 | HGNC ID: HGNC:21726 | Ensembl Gene: ENSG00000110237 | OMIM ID: 617043 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGEF17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGEF17 | 9828 | 203756_at | 0.1753 | 0.6532 | |
| GSE20347 | ARHGEF17 | 9828 | 203756_at | 0.1682 | 0.0346 | |
| GSE23400 | ARHGEF17 | 9828 | 203756_at | 0.0888 | 0.1425 | |
| GSE26886 | ARHGEF17 | 9828 | 203756_at | 0.3498 | 0.0029 | |
| GSE29001 | ARHGEF17 | 9828 | 203756_at | 0.0965 | 0.6515 | |
| GSE38129 | ARHGEF17 | 9828 | 203756_at | -0.1676 | 0.1682 | |
| GSE45670 | ARHGEF17 | 9828 | 203756_at | -0.1509 | 0.1943 | |
| GSE53622 | ARHGEF17 | 9828 | 84102 | 0.1444 | 0.2540 | |
| GSE53624 | ARHGEF17 | 9828 | 84102 | 0.4625 | 0.0000 | |
| GSE63941 | ARHGEF17 | 9828 | 203756_at | -0.2373 | 0.4831 | |
| GSE77861 | ARHGEF17 | 9828 | 203756_at | 0.1424 | 0.1494 | |
| GSE97050 | ARHGEF17 | 9828 | A_23_P76015 | -0.1702 | 0.5703 | |
| SRP007169 | ARHGEF17 | 9828 | RNAseq | 1.5056 | 0.0005 | |
| SRP008496 | ARHGEF17 | 9828 | RNAseq | 2.5151 | 0.0000 | |
| SRP064894 | ARHGEF17 | 9828 | RNAseq | 0.9334 | 0.0000 | |
| SRP133303 | ARHGEF17 | 9828 | RNAseq | 0.4266 | 0.1088 | |
| SRP159526 | ARHGEF17 | 9828 | RNAseq | 0.0564 | 0.8872 | |
| SRP193095 | ARHGEF17 | 9828 | RNAseq | 1.2902 | 0.0000 | |
| SRP219564 | ARHGEF17 | 9828 | RNAseq | 0.2010 | 0.7269 | |
| TCGA | ARHGEF17 | 9828 | RNAseq | -0.2126 | 0.0093 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ARHGEF17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGEF17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGEF17 | 9828 | 7 | 8 | 15 | |
| GSE20123 | ARHGEF17 | 9828 | 7 | 7 | 16 | |
| GSE43470 | ARHGEF17 | 9828 | 9 | 2 | 32 | |
| GSE46452 | ARHGEF17 | 9828 | 10 | 19 | 30 | |
| GSE47630 | ARHGEF17 | 9828 | 7 | 13 | 20 | |
| GSE54993 | ARHGEF17 | 9828 | 8 | 2 | 60 | |
| GSE54994 | ARHGEF17 | 9828 | 8 | 15 | 30 | |
| GSE60625 | ARHGEF17 | 9828 | 0 | 7 | 4 | |
| GSE74703 | ARHGEF17 | 9828 | 7 | 2 | 27 | |
| GSE74704 | ARHGEF17 | 9828 | 5 | 3 | 12 | |
| TCGA | ARHGEF17 | 9828 | 28 | 27 | 41 |
Total number of gains: 96; Total number of losses: 105; Total Number of normals: 287.
Somatic mutations of ARHGEF17:
Generating mutation plots.
Highly correlated genes for ARHGEF17:
Showing top 20/577 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGEF17 | PRPH | 0.703064 | 4 | 0 | 4 |
| ARHGEF17 | TMPRSS5 | 0.686741 | 3 | 0 | 3 |
| ARHGEF17 | NACAD | 0.682602 | 5 | 0 | 5 |
| ARHGEF17 | SLC12A9 | 0.665523 | 3 | 0 | 3 |
| ARHGEF17 | TMEM151A | 0.660073 | 3 | 0 | 3 |
| ARHGEF17 | CDH7 | 0.659159 | 3 | 0 | 3 |
| ARHGEF17 | DGKZ | 0.657061 | 3 | 0 | 3 |
| ARHGEF17 | KHSRP | 0.654058 | 3 | 0 | 3 |
| ARHGEF17 | KBTBD2 | 0.65138 | 3 | 0 | 3 |
| ARHGEF17 | RPL3L | 0.651137 | 4 | 0 | 4 |
| ARHGEF17 | TESPA1 | 0.650229 | 3 | 0 | 3 |
| ARHGEF17 | RAMP1 | 0.644734 | 7 | 0 | 6 |
| ARHGEF17 | RASD2 | 0.643761 | 4 | 0 | 4 |
| ARHGEF17 | SMARCA1 | 0.638228 | 5 | 0 | 5 |
| ARHGEF17 | KIAA0930 | 0.637313 | 3 | 0 | 3 |
| ARHGEF17 | FURIN | 0.637217 | 5 | 0 | 4 |
| ARHGEF17 | PHF1 | 0.636048 | 5 | 0 | 4 |
| ARHGEF17 | TGFB1I1 | 0.632784 | 9 | 0 | 7 |
| ARHGEF17 | FOXF2 | 0.629544 | 10 | 0 | 9 |
| ARHGEF17 | GLI1 | 0.628746 | 4 | 0 | 3 |
For details and further investigation, click here
