| Full name: PHD finger protein 1 | Alias Symbol: MTF2L2|TDRD19C|PCL1 | ||
| Type: protein-coding gene | Cytoband: 6p21.32 | ||
| Entrez ID: 5252 | HGNC ID: HGNC:8919 | Ensembl Gene: ENSG00000112511 | OMIM ID: 602881 |
| Drug and gene relationship at DGIdb | |||
Expression of PHF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHF1 | 5252 | 40446_at | -0.0544 | 0.9297 | |
| GSE20347 | PHF1 | 5252 | 40446_at | 0.1202 | 0.2673 | |
| GSE23400 | PHF1 | 5252 | 40446_at | -0.1063 | 0.0482 | |
| GSE26886 | PHF1 | 5252 | 40446_at | 0.9529 | 0.0000 | |
| GSE29001 | PHF1 | 5252 | 40446_at | -0.0531 | 0.9018 | |
| GSE38129 | PHF1 | 5252 | 40446_at | -0.1528 | 0.3108 | |
| GSE45670 | PHF1 | 5252 | 40446_at | -0.3176 | 0.0076 | |
| GSE53622 | PHF1 | 5252 | 130551 | -0.0361 | 0.6281 | |
| GSE53624 | PHF1 | 5252 | 130551 | -0.0770 | 0.1635 | |
| GSE63941 | PHF1 | 5252 | 40446_at | -0.5122 | 0.0657 | |
| GSE77861 | PHF1 | 5252 | 40446_at | 0.0196 | 0.9547 | |
| GSE97050 | PHF1 | 5252 | A_23_P156732 | -0.1274 | 0.6005 | |
| SRP007169 | PHF1 | 5252 | RNAseq | 0.2511 | 0.5206 | |
| SRP008496 | PHF1 | 5252 | RNAseq | 0.2622 | 0.3787 | |
| SRP064894 | PHF1 | 5252 | RNAseq | 0.0194 | 0.9129 | |
| SRP133303 | PHF1 | 5252 | RNAseq | -0.3115 | 0.1158 | |
| SRP159526 | PHF1 | 5252 | RNAseq | -0.0743 | 0.7602 | |
| SRP193095 | PHF1 | 5252 | RNAseq | 0.3572 | 0.0031 | |
| SRP219564 | PHF1 | 5252 | RNAseq | -0.0491 | 0.8923 | |
| TCGA | PHF1 | 5252 | RNAseq | -0.1914 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PHF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHF1 | 5252 | 5 | 0 | 25 | |
| GSE20123 | PHF1 | 5252 | 5 | 0 | 25 | |
| GSE43470 | PHF1 | 5252 | 4 | 1 | 38 | |
| GSE46452 | PHF1 | 5252 | 2 | 9 | 48 | |
| GSE47630 | PHF1 | 5252 | 8 | 4 | 28 | |
| GSE54993 | PHF1 | 5252 | 3 | 1 | 66 | |
| GSE54994 | PHF1 | 5252 | 11 | 4 | 38 | |
| GSE60625 | PHF1 | 5252 | 1 | 0 | 10 | |
| GSE74703 | PHF1 | 5252 | 4 | 0 | 32 | |
| GSE74704 | PHF1 | 5252 | 2 | 0 | 18 | |
| TCGA | PHF1 | 5252 | 15 | 16 | 65 |
Total number of gains: 60; Total number of losses: 35; Total Number of normals: 393.
Somatic mutations of PHF1:
Generating mutation plots.
Highly correlated genes for PHF1:
Showing top 20/306 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHF1 | PNMA6A | 0.867036 | 3 | 0 | 3 |
| PHF1 | SHISA4 | 0.791433 | 3 | 0 | 3 |
| PHF1 | C19orf44 | 0.777826 | 3 | 0 | 3 |
| PHF1 | FCN2 | 0.735119 | 3 | 0 | 3 |
| PHF1 | MAPK8IP2 | 0.73223 | 4 | 0 | 3 |
| PHF1 | CABP2 | 0.726633 | 3 | 0 | 3 |
| PHF1 | PKDREJ | 0.72161 | 3 | 0 | 3 |
| PHF1 | PIP5KL1 | 0.720365 | 3 | 0 | 3 |
| PHF1 | FXYD2 | 0.718969 | 4 | 0 | 3 |
| PHF1 | PRKCG | 0.71609 | 3 | 0 | 3 |
| PHF1 | USH1C | 0.713178 | 3 | 0 | 3 |
| PHF1 | TSKS | 0.708172 | 3 | 0 | 3 |
| PHF1 | MOK | 0.702314 | 3 | 0 | 3 |
| PHF1 | GNB3 | 0.701841 | 3 | 0 | 3 |
| PHF1 | ARL8A | 0.699327 | 4 | 0 | 3 |
| PHF1 | TTLL9 | 0.691653 | 3 | 0 | 3 |
| PHF1 | TRPA1 | 0.691522 | 3 | 0 | 3 |
| PHF1 | DNLZ | 0.689795 | 3 | 0 | 3 |
| PHF1 | IQSEC3 | 0.688726 | 3 | 0 | 3 |
| PHF1 | KAZALD1 | 0.686491 | 3 | 0 | 3 |
For details and further investigation, click here
