| Full name: ankyrin repeat and SOCS box containing 14 | Alias Symbol: DKFZp313L0121 | ||
| Type: protein-coding gene | Cytoband: 3p14.3 | ||
| Entrez ID: 142686 | HGNC ID: HGNC:19766 | Ensembl Gene: ENSG00000239388 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ASB14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASB14 | 142686 | 1553453_at | 0.0350 | 0.8955 | |
| GSE26886 | ASB14 | 142686 | 1553453_at | -0.0713 | 0.5280 | |
| GSE45670 | ASB14 | 142686 | 237785_at | 0.0567 | 0.5836 | |
| GSE53622 | ASB14 | 142686 | 11453 | -0.8652 | 0.0000 | |
| GSE53624 | ASB14 | 142686 | 11453 | -0.7793 | 0.0000 | |
| GSE63941 | ASB14 | 142686 | 237785_at | -0.0511 | 0.7583 | |
| GSE77861 | ASB14 | 142686 | 1553453_at | -0.1059 | 0.1532 | |
| GSE97050 | ASB14 | 142686 | A_33_P3290144 | 0.0630 | 0.8138 | |
| SRP133303 | ASB14 | 142686 | RNAseq | -0.8752 | 0.0000 | |
| SRP159526 | ASB14 | 142686 | RNAseq | -1.5290 | 0.0005 | |
| SRP193095 | ASB14 | 142686 | RNAseq | -0.8472 | 0.0000 | |
| SRP219564 | ASB14 | 142686 | RNAseq | -0.9289 | 0.1104 | |
| TCGA | ASB14 | 142686 | RNAseq | -0.6271 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ASB14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASB14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASB14 | 142686 | 0 | 17 | 13 | |
| GSE20123 | ASB14 | 142686 | 0 | 18 | 12 | |
| GSE43470 | ASB14 | 142686 | 0 | 17 | 26 | |
| GSE46452 | ASB14 | 142686 | 2 | 17 | 40 | |
| GSE47630 | ASB14 | 142686 | 1 | 24 | 15 | |
| GSE54993 | ASB14 | 142686 | 6 | 2 | 62 | |
| GSE54994 | ASB14 | 142686 | 0 | 32 | 21 | |
| GSE60625 | ASB14 | 142686 | 5 | 0 | 6 | |
| GSE74703 | ASB14 | 142686 | 0 | 14 | 22 | |
| GSE74704 | ASB14 | 142686 | 0 | 11 | 9 | |
| TCGA | ASB14 | 142686 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 231; Total Number of normals: 243.
Somatic mutations of ASB14:
Generating mutation plots.
Highly correlated genes for ASB14:
Showing top 20/66 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASB14 | ZMYM5 | 0.667293 | 3 | 0 | 3 |
| ASB14 | FBXO8 | 0.646718 | 3 | 0 | 3 |
| ASB14 | CAPN7 | 0.642047 | 3 | 0 | 3 |
| ASB14 | FAM209B | 0.630508 | 4 | 0 | 4 |
| ASB14 | EMC3 | 0.629903 | 3 | 0 | 3 |
| ASB14 | KAT2B | 0.627112 | 3 | 0 | 3 |
| ASB14 | C7orf57 | 0.623985 | 3 | 0 | 3 |
| ASB14 | CTTNBP2NL | 0.622773 | 3 | 0 | 3 |
| ASB14 | LIPM | 0.620517 | 3 | 0 | 3 |
| ASB14 | ZNF654 | 0.619694 | 3 | 0 | 3 |
| ASB14 | DLGAP3 | 0.613358 | 3 | 0 | 3 |
| ASB14 | DENND4C | 0.607248 | 3 | 0 | 3 |
| ASB14 | GSKIP | 0.606956 | 3 | 0 | 3 |
| ASB14 | BRK1 | 0.602353 | 3 | 0 | 3 |
| ASB14 | DHX32 | 0.596527 | 3 | 0 | 3 |
| ASB14 | JAK2 | 0.594146 | 4 | 0 | 3 |
| ASB14 | FBXW7 | 0.592841 | 3 | 0 | 3 |
| ASB14 | CDK7 | 0.592372 | 4 | 0 | 4 |
| ASB14 | SLC30A9 | 0.592242 | 3 | 0 | 3 |
| ASB14 | MPP7 | 0.586221 | 3 | 0 | 3 |
For details and further investigation, click here
