| Full name: GSK3B interacting protein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.2 | ||
| Entrez ID: 51527 | HGNC ID: HGNC:20343 | Ensembl Gene: ENSG00000100744 | OMIM ID: 616605 |
| Drug and gene relationship at DGIdb | |||
Expression of GSKIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSKIP | 51527 | 223239_at | -0.4954 | 0.4990 | |
| GSE26886 | GSKIP | 51527 | 223239_at | -2.0042 | 0.0000 | |
| GSE45670 | GSKIP | 51527 | 223239_at | -0.2334 | 0.1974 | |
| GSE53622 | GSKIP | 51527 | 90522 | -0.9077 | 0.0000 | |
| GSE53624 | GSKIP | 51527 | 90522 | -1.1704 | 0.0000 | |
| GSE63941 | GSKIP | 51527 | 223239_at | -0.4810 | 0.2941 | |
| GSE77861 | GSKIP | 51527 | 223239_at | -1.2546 | 0.0197 | |
| SRP007169 | GSKIP | 51527 | RNAseq | -2.1316 | 0.0000 | |
| SRP008496 | GSKIP | 51527 | RNAseq | -1.9599 | 0.0000 | |
| SRP064894 | GSKIP | 51527 | RNAseq | -1.1166 | 0.0000 | |
| SRP133303 | GSKIP | 51527 | RNAseq | -0.6397 | 0.0003 | |
| SRP159526 | GSKIP | 51527 | RNAseq | -1.4842 | 0.0000 | |
| SRP193095 | GSKIP | 51527 | RNAseq | -1.5787 | 0.0000 | |
| SRP219564 | GSKIP | 51527 | RNAseq | -1.3492 | 0.0126 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by GSKIP expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of GSKIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSKIP | 51527 | 10 | 4 | 16 | |
| GSE20123 | GSKIP | 51527 | 10 | 3 | 17 | |
| GSE43470 | GSKIP | 51527 | 8 | 3 | 32 | |
| GSE46452 | GSKIP | 51527 | 17 | 3 | 39 | |
| GSE47630 | GSKIP | 51527 | 11 | 8 | 21 | |
| GSE54993 | GSKIP | 51527 | 3 | 8 | 59 | |
| GSE54994 | GSKIP | 51527 | 21 | 4 | 28 | |
| GSE60625 | GSKIP | 51527 | 0 | 2 | 9 | |
| GSE74703 | GSKIP | 51527 | 6 | 3 | 27 | |
| GSE74704 | GSKIP | 51527 | 6 | 3 | 11 | |
| TCGA | GSKIP | 51527 | 30 | 19 | 47 |
Total number of gains: 122; Total number of losses: 60; Total Number of normals: 306.
Somatic mutations of GSKIP:
Generating mutation plots.
Highly correlated genes for GSKIP:
Showing top 20/1190 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSKIP | DUSP11 | 0.797639 | 3 | 0 | 3 |
| GSKIP | VPS4B | 0.795804 | 6 | 0 | 6 |
| GSKIP | TWF1 | 0.791947 | 6 | 0 | 6 |
| GSKIP | CD2AP | 0.781564 | 4 | 0 | 4 |
| GSKIP | CAPN14 | 0.780012 | 6 | 0 | 6 |
| GSKIP | PDCD6IP | 0.77994 | 6 | 0 | 6 |
| GSKIP | S100A14 | 0.778879 | 6 | 0 | 6 |
| GSKIP | EMC3 | 0.775084 | 6 | 0 | 6 |
| GSKIP | CWH43 | 0.772673 | 6 | 0 | 6 |
| GSKIP | BTBD11 | 0.772024 | 6 | 0 | 6 |
| GSKIP | CES2 | 0.77122 | 4 | 0 | 4 |
| GSKIP | EP300-AS1 | 0.765535 | 3 | 0 | 3 |
| GSKIP | TMOD3 | 0.765388 | 6 | 0 | 6 |
| GSKIP | MPP5 | 0.764936 | 6 | 0 | 6 |
| GSKIP | SERPINB1 | 0.764485 | 6 | 0 | 6 |
| GSKIP | SPTLC1 | 0.763083 | 6 | 0 | 6 |
| GSKIP | ARF6 | 0.762708 | 6 | 0 | 6 |
| GSKIP | BNIPL | 0.76224 | 6 | 0 | 6 |
| GSKIP | GPR157 | 0.761347 | 6 | 0 | 6 |
| GSKIP | S100A16 | 0.758417 | 6 | 0 | 6 |
For details and further investigation, click here
