| Full name: chromosome 7 open reading frame 57 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p12.3 | ||
| Entrez ID: 136288 | HGNC ID: HGNC:22247 | Ensembl Gene: ENSG00000164746 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C7orf57:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C7orf57 | 136288 | 1557636_a_at | -0.9169 | 0.3919 | |
| GSE26886 | C7orf57 | 136288 | 1557636_a_at | -0.5208 | 0.0095 | |
| GSE45670 | C7orf57 | 136288 | 1557636_a_at | -0.3771 | 0.3390 | |
| GSE53622 | C7orf57 | 136288 | 5748 | -1.6406 | 0.0000 | |
| GSE53624 | C7orf57 | 136288 | 5748 | -2.6044 | 0.0000 | |
| GSE63941 | C7orf57 | 136288 | 1557636_a_at | 0.4881 | 0.6106 | |
| GSE77861 | C7orf57 | 136288 | 1557636_a_at | -0.3676 | 0.0078 | |
| SRP133303 | C7orf57 | 136288 | RNAseq | -0.2442 | 0.6416 | |
| SRP159526 | C7orf57 | 136288 | RNAseq | -2.5644 | 0.0028 | |
| TCGA | C7orf57 | 136288 | RNAseq | 0.9754 | 0.0266 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by C7orf57 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C7orf57:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C7orf57 | 136288 | 13 | 0 | 17 | |
| GSE20123 | C7orf57 | 136288 | 12 | 0 | 18 | |
| GSE43470 | C7orf57 | 136288 | 4 | 0 | 39 | |
| GSE46452 | C7orf57 | 136288 | 11 | 1 | 47 | |
| GSE47630 | C7orf57 | 136288 | 8 | 1 | 31 | |
| GSE54993 | C7orf57 | 136288 | 0 | 8 | 62 | |
| GSE54994 | C7orf57 | 136288 | 16 | 3 | 34 | |
| GSE60625 | C7orf57 | 136288 | 0 | 0 | 11 | |
| GSE74703 | C7orf57 | 136288 | 4 | 0 | 32 | |
| GSE74704 | C7orf57 | 136288 | 6 | 0 | 14 | |
| TCGA | C7orf57 | 136288 | 51 | 8 | 37 |
Total number of gains: 125; Total number of losses: 21; Total Number of normals: 342.
Somatic mutations of C7orf57:
Generating mutation plots.
Highly correlated genes for C7orf57:
Showing top 20/1038 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C7orf57 | MXD1 | 0.789273 | 6 | 0 | 6 |
| C7orf57 | MPZL3 | 0.762638 | 6 | 0 | 6 |
| C7orf57 | ANKRD37 | 0.761718 | 4 | 0 | 4 |
| C7orf57 | GRPEL2 | 0.754869 | 6 | 0 | 6 |
| C7orf57 | TMEM40 | 0.752681 | 6 | 0 | 6 |
| C7orf57 | IL22RA1 | 0.74548 | 4 | 0 | 4 |
| C7orf57 | ATG9B | 0.743608 | 6 | 0 | 6 |
| C7orf57 | PIM1 | 0.74214 | 6 | 0 | 6 |
| C7orf57 | SH3GL1 | 0.741995 | 6 | 0 | 6 |
| C7orf57 | PDLIM2 | 0.741583 | 4 | 0 | 4 |
| C7orf57 | YOD1 | 0.739208 | 6 | 0 | 6 |
| C7orf57 | RAET1E | 0.736916 | 6 | 0 | 5 |
| C7orf57 | TMOD3 | 0.734793 | 6 | 0 | 6 |
| C7orf57 | RANBP9 | 0.734699 | 6 | 0 | 6 |
| C7orf57 | PRDM1 | 0.733534 | 6 | 0 | 6 |
| C7orf57 | CYSRT1 | 0.730989 | 6 | 0 | 6 |
| C7orf57 | DENND2C | 0.730341 | 6 | 0 | 6 |
| C7orf57 | ENDOU | 0.728679 | 6 | 0 | 6 |
| C7orf57 | TRIP10 | 0.727399 | 6 | 0 | 6 |
| C7orf57 | MSMO1 | 0.726326 | 6 | 0 | 6 |
For details and further investigation, click here
