CAPN7

 

Full name: calpain 7 Alias Symbol: PalBH
Type: protein-coding gene Cytoband: 3p25.1
Entrez ID: 23473 HGNC ID: HGNC:1484 Ensembl Gene: ENSG00000131375 OMIM ID: 606400
Drug and gene relationship at DGIdb

 

Expression of CAPN7:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CAPN7 23473 203356_at -0.5559 0.1530
GSE20347 CAPN7 23473 203356_at -0.6683 0.0018
GSE23400 CAPN7 23473 203357_s_at -0.2602 0.0037
GSE26886 CAPN7 23473 203356_at -1.9705 0.0000
GSE29001 CAPN7 23473 203356_at -0.4934 0.1722
GSE38129 CAPN7 23473 203356_at -0.6426 0.0001
GSE45670 CAPN7 23473 203356_at -0.5575 0.0000
GSE53622 CAPN7 23473 13223 -0.6598 0.0000
GSE53624 CAPN7 23473 13223 -0.7504 0.0000
GSE63941 CAPN7 23473 203356_at -0.3918 0.3914
GSE77861 CAPN7 23473 203356_at -0.8551 0.0020
GSE97050 CAPN7 23473 A_33_P3393175 -0.0681 0.7494
SRP007169 CAPN7 23473 RNAseq -0.5325 0.1305
SRP008496 CAPN7 23473 RNAseq -0.3467 0.1758
SRP064894 CAPN7 23473 RNAseq -0.7593 0.0000
SRP133303 CAPN7 23473 RNAseq -0.4799 0.0000
SRP159526 CAPN7 23473 RNAseq -0.6123 0.0186
SRP193095 CAPN7 23473 RNAseq -0.6187 0.0000
SRP219564 CAPN7 23473 RNAseq -0.5168 0.1978
TCGA CAPN7 23473 RNAseq -0.2577 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by CAPN7 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CAPN7:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CAPN7 23473 2 18 10
GSE20123 CAPN7 23473 2 18 10
GSE43470 CAPN7 23473 0 21 22
GSE46452 CAPN7 23473 2 17 40
GSE47630 CAPN7 23473 2 23 15
GSE54993 CAPN7 23473 6 1 63
GSE54994 CAPN7 23473 1 32 20
GSE60625 CAPN7 23473 5 0 6
GSE74703 CAPN7 23473 0 17 19
GSE74704 CAPN7 23473 1 12 7
TCGA CAPN7 23473 2 68 26

Total number of gains: 23; Total number of losses: 227; Total Number of normals: 238.  


 

Somatic mutations of CAPN7:

 

Generating mutation plots.

 

Highly correlated genes for CAPN7:

 

Showing top 20/1588 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CAPN7RHBDF10.823118303
CAPN7ZNF4160.782996403
CAPN7ZDHHC210.749485403
CAPN7ZNF920.749433303
CAPN7BRK10.746889707
CAPN7C5orf510.741808303
CAPN7NFIA0.739427706
CAPN7PDK30.737253303
CAPN7WDFY10.735012404
CAPN7CCNYL10.733394403
CAPN7SUCLG20.73161812010
CAPN7KCTD60.731049707
CAPN7EIF4E30.730127807
CAPN7SLC44A30.730082605
CAPN7ANO80.72859303
CAPN7HDHD20.728389505
CAPN7RBM200.728031504
CAPN7PPP1R80.727659303
CAPN7FBXL30.724499605
CAPN7KLHDC10.723051606

For details and further investigation, click here