| Full name: RAB8B, member RAS oncogene family | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q22.2 | ||
| Entrez ID: 51762 | HGNC ID: HGNC:30273 | Ensembl Gene: ENSG00000166128 | OMIM ID: 613532 |
| Drug and gene relationship at DGIdb | |||
Expression of RAB8B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB8B | 51762 | 226633_at | -0.3175 | 0.6144 | |
| GSE20347 | RAB8B | 51762 | 219210_s_at | 0.6677 | 0.0003 | |
| GSE23400 | RAB8B | 51762 | 219210_s_at | 0.2482 | 0.0000 | |
| GSE26886 | RAB8B | 51762 | 226633_at | 0.6130 | 0.0671 | |
| GSE29001 | RAB8B | 51762 | 219210_s_at | 0.6270 | 0.0050 | |
| GSE38129 | RAB8B | 51762 | 219210_s_at | 0.7309 | 0.0000 | |
| GSE45670 | RAB8B | 51762 | 226633_at | -0.7915 | 0.0143 | |
| GSE53622 | RAB8B | 51762 | 61604 | 0.0284 | 0.8395 | |
| GSE53624 | RAB8B | 51762 | 61604 | -0.1667 | 0.2382 | |
| GSE63941 | RAB8B | 51762 | 226633_at | -2.5658 | 0.0002 | |
| GSE77861 | RAB8B | 51762 | 226633_at | 0.5020 | 0.1340 | |
| GSE97050 | RAB8B | 51762 | A_23_P317465 | 0.0391 | 0.8977 | |
| SRP007169 | RAB8B | 51762 | RNAseq | 1.0625 | 0.0275 | |
| SRP008496 | RAB8B | 51762 | RNAseq | 1.2560 | 0.0000 | |
| SRP064894 | RAB8B | 51762 | RNAseq | 0.3517 | 0.2546 | |
| SRP133303 | RAB8B | 51762 | RNAseq | 0.1347 | 0.5351 | |
| SRP159526 | RAB8B | 51762 | RNAseq | -0.4367 | 0.2707 | |
| SRP193095 | RAB8B | 51762 | RNAseq | 0.4676 | 0.0194 | |
| SRP219564 | RAB8B | 51762 | RNAseq | 0.2594 | 0.3823 | |
| TCGA | RAB8B | 51762 | RNAseq | -0.1580 | 0.0371 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by RAB8B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB8B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB8B | 51762 | 8 | 2 | 20 | |
| GSE20123 | RAB8B | 51762 | 8 | 2 | 20 | |
| GSE43470 | RAB8B | 51762 | 4 | 6 | 33 | |
| GSE46452 | RAB8B | 51762 | 3 | 7 | 49 | |
| GSE47630 | RAB8B | 51762 | 8 | 10 | 22 | |
| GSE54993 | RAB8B | 51762 | 5 | 6 | 59 | |
| GSE54994 | RAB8B | 51762 | 6 | 8 | 39 | |
| GSE60625 | RAB8B | 51762 | 4 | 0 | 7 | |
| GSE74703 | RAB8B | 51762 | 4 | 3 | 29 | |
| GSE74704 | RAB8B | 51762 | 4 | 2 | 14 | |
| TCGA | RAB8B | 51762 | 10 | 17 | 69 |
Total number of gains: 64; Total number of losses: 63; Total Number of normals: 361.
Somatic mutations of RAB8B:
Generating mutation plots.
Highly correlated genes for RAB8B:
Showing top 20/1105 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB8B | JMY | 0.838892 | 3 | 0 | 3 |
| RAB8B | LRRK2 | 0.791023 | 3 | 0 | 3 |
| RAB8B | TMED8 | 0.775915 | 3 | 0 | 3 |
| RAB8B | C19orf38 | 0.7642 | 3 | 0 | 3 |
| RAB8B | PREX1 | 0.761188 | 3 | 0 | 3 |
| RAB8B | CD163L1 | 0.751149 | 3 | 0 | 3 |
| RAB8B | GIMAP5 | 0.750571 | 3 | 0 | 3 |
| RAB8B | TYW3 | 0.742864 | 4 | 0 | 3 |
| RAB8B | UFSP2 | 0.739964 | 3 | 0 | 3 |
| RAB8B | PTGFRN | 0.738102 | 3 | 0 | 3 |
| RAB8B | STAT2 | 0.737308 | 4 | 0 | 4 |
| RAB8B | ATG10 | 0.73447 | 3 | 0 | 3 |
| RAB8B | CD226 | 0.727314 | 3 | 0 | 3 |
| RAB8B | PTPRD | 0.726773 | 3 | 0 | 3 |
| RAB8B | GPC6 | 0.726251 | 6 | 0 | 6 |
| RAB8B | GIMAP1 | 0.722609 | 5 | 0 | 5 |
| RAB8B | IL6 | 0.722521 | 4 | 0 | 4 |
| RAB8B | BHLHE22 | 0.719235 | 5 | 0 | 5 |
| RAB8B | AXL | 0.719171 | 7 | 0 | 6 |
| RAB8B | DOK6 | 0.717532 | 4 | 0 | 4 |
For details and further investigation, click here
