| Full name: ATPase secretory pathway Ca2+ transporting 2 | Alias Symbol: KIAA0703|SPCA2 | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 9914 | HGNC ID: HGNC:29103 | Ensembl Gene: ENSG00000064270 | OMIM ID: 613082 |
| Drug and gene relationship at DGIdb | |||
Expression of ATP2C2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP2C2 | 9914 | 206043_s_at | 0.9872 | 0.2578 | |
| GSE20347 | ATP2C2 | 9914 | 214798_at | 0.2693 | 0.1090 | |
| GSE23400 | ATP2C2 | 9914 | 206043_s_at | 0.2647 | 0.0046 | |
| GSE26886 | ATP2C2 | 9914 | 214798_at | 0.3136 | 0.3196 | |
| GSE29001 | ATP2C2 | 9914 | 214798_at | 0.7584 | 0.0695 | |
| GSE38129 | ATP2C2 | 9914 | 214798_at | 0.4429 | 0.0167 | |
| GSE45670 | ATP2C2 | 9914 | 214798_at | 0.2664 | 0.3331 | |
| GSE53622 | ATP2C2 | 9914 | 28888 | 0.9472 | 0.0040 | |
| GSE53624 | ATP2C2 | 9914 | 28888 | 0.6771 | 0.0013 | |
| GSE63941 | ATP2C2 | 9914 | 214798_at | 0.6084 | 0.2549 | |
| GSE77861 | ATP2C2 | 9914 | 214798_at | 0.0398 | 0.8255 | |
| GSE97050 | ATP2C2 | 9914 | A_23_P117992 | 0.7522 | 0.1512 | |
| SRP064894 | ATP2C2 | 9914 | RNAseq | -0.3071 | 0.5323 | |
| SRP133303 | ATP2C2 | 9914 | RNAseq | 0.5417 | 0.2340 | |
| SRP159526 | ATP2C2 | 9914 | RNAseq | 1.5030 | 0.0346 | |
| SRP193095 | ATP2C2 | 9914 | RNAseq | 0.8165 | 0.0145 | |
| SRP219564 | ATP2C2 | 9914 | RNAseq | 1.1693 | 0.2240 | |
| TCGA | ATP2C2 | 9914 | RNAseq | 0.3628 | 0.1392 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ATP2C2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP2C2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP2C2 | 9914 | 4 | 4 | 22 | |
| GSE20123 | ATP2C2 | 9914 | 4 | 4 | 22 | |
| GSE43470 | ATP2C2 | 9914 | 2 | 10 | 31 | |
| GSE46452 | ATP2C2 | 9914 | 37 | 2 | 20 | |
| GSE47630 | ATP2C2 | 9914 | 11 | 9 | 20 | |
| GSE54993 | ATP2C2 | 9914 | 3 | 4 | 63 | |
| GSE54994 | ATP2C2 | 9914 | 8 | 10 | 35 | |
| GSE60625 | ATP2C2 | 9914 | 4 | 0 | 7 | |
| GSE74703 | ATP2C2 | 9914 | 2 | 7 | 27 | |
| GSE74704 | ATP2C2 | 9914 | 3 | 2 | 15 | |
| TCGA | ATP2C2 | 9914 | 26 | 16 | 54 |
Total number of gains: 104; Total number of losses: 68; Total Number of normals: 316.
Somatic mutations of ATP2C2:
Generating mutation plots.
Highly correlated genes for ATP2C2:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP2C2 | PRPS2 | 0.747211 | 3 | 0 | 3 |
| ATP2C2 | RSBN1L | 0.740949 | 3 | 0 | 3 |
| ATP2C2 | CDCA2 | 0.740162 | 3 | 0 | 3 |
| ATP2C2 | FARS2 | 0.733511 | 3 | 0 | 3 |
| ATP2C2 | DHRS13 | 0.715371 | 3 | 0 | 3 |
| ATP2C2 | XPO7 | 0.708781 | 3 | 0 | 3 |
| ATP2C2 | MFHAS1 | 0.707674 | 4 | 0 | 4 |
| ATP2C2 | ABCE1 | 0.700819 | 3 | 0 | 3 |
| ATP2C2 | ZSWIM1 | 0.699646 | 5 | 0 | 4 |
| ATP2C2 | ZNF594 | 0.695109 | 4 | 0 | 4 |
| ATP2C2 | MGAT4B | 0.688853 | 4 | 0 | 3 |
| ATP2C2 | TFAM | 0.684284 | 3 | 0 | 3 |
| ATP2C2 | GET4 | 0.681546 | 3 | 0 | 3 |
| ATP2C2 | TTC4 | 0.680649 | 4 | 0 | 3 |
| ATP2C2 | TOP3A | 0.672443 | 4 | 0 | 4 |
| ATP2C2 | TP53I11 | 0.665377 | 3 | 0 | 3 |
| ATP2C2 | BTF3L4 | 0.663642 | 3 | 0 | 3 |
| ATP2C2 | THADA | 0.661213 | 3 | 0 | 3 |
| ATP2C2 | ZBTB25 | 0.656926 | 3 | 0 | 3 |
| ATP2C2 | RAD18 | 0.654333 | 4 | 0 | 3 |
For details and further investigation, click here
